Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | LPC26_RS10260 | Genome accession | NZ_AP025162 |
| Coordinates | 2084674..2086836 (-) | Length | 720 a.a. |
| NCBI ID | WP_068813212.1 | Uniprot ID | A0A2N5KWZ3 |
| Organism | Lactobacillus crispatus strain KT-11 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 2061478..2090924 | 2084674..2086836 | within | 0 |
Gene organization within MGE regions
Location: 2061478..2090924
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPC26_RS10100 | - | 2061478..2062371 (-) | 894 | WP_005718198.1 | C40 family peptidase | - |
| LPC26_RS10105 | - | 2062541..2063284 (-) | 744 | WP_005726403.1 | C40 family peptidase | - |
| LPC26_RS10110 | - | 2063553..2064101 (-) | 549 | WP_060461568.1 | C40 family peptidase | - |
| LPC26_RS10115 | - | 2064272..2064814 (-) | 543 | WP_005718194.1 | guanylate kinase | - |
| LPC26_RS10120 | - | 2064911..2065213 (+) | 303 | WP_005718193.1 | DUF2187 family protein | - |
| LPC26_RS10125 | - | 2065299..2066807 (+) | 1509 | WP_005725484.1 | O-antigen ligase family protein | - |
| LPC26_RS10130 | - | 2066862..2067485 (-) | 624 | WP_005722447.1 | LVIS_2131 family protein | - |
| LPC26_RS10135 | nrdI | 2067610..2068056 (+) | 447 | WP_060461569.1 | class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI | - |
| LPC26_RS10140 | - | 2068059..2068994 (+) | 936 | WP_005725481.1 | ribonucleotide-diphosphate reductase subunit beta | - |
| LPC26_RS10145 | - | 2069034..2069564 (-) | 531 | WP_005718185.1 | hypothetical protein | - |
| LPC26_RS10150 | - | 2069681..2070394 (+) | 714 | WP_013086905.1 | C39 family peptidase | - |
| LPC26_RS10155 | - | 2070590..2071075 (-) | 486 | WP_005718183.1 | threonine/serine exporter family protein | - |
| LPC26_RS10160 | - | 2071078..2071848 (-) | 771 | WP_060461570.1 | threonine/serine exporter family protein | - |
| LPC26_RS10165 | - | 2071859..2073400 (-) | 1542 | WP_229265788.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| LPC26_RS10170 | - | 2073418..2073795 (-) | 378 | WP_060461572.1 | hypothetical protein | - |
| LPC26_RS10175 | - | 2073941..2074492 (+) | 552 | WP_060461573.1 | GNAT family N-acetyltransferase | - |
| LPC26_RS10180 | - | 2074489..2075178 (-) | 690 | WP_005718174.1 | DUF554 domain-containing protein | - |
| LPC26_RS10185 | - | 2075243..2076481 (-) | 1239 | WP_060461574.1 | LCP family protein | - |
| LPC26_RS10190 | pepF | 2076649..2078445 (+) | 1797 | WP_060461575.1 | oligoendopeptidase F | Regulator |
| LPC26_RS10195 | - | 2078598..2078813 (+) | 216 | WP_005723825.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| LPC26_RS10200 | - | 2078817..2079224 (+) | 408 | WP_060461576.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| LPC26_RS10205 | - | 2079338..2079613 (-) | 276 | WP_005723823.1 | bacteriocin immunity protein | - |
| LPC26_RS10210 | - | 2079617..2079835 (-) | 219 | WP_005726358.1 | TIGR04139 family peptide modification target | - |
| LPC26_RS10215 | - | 2080009..2080305 (-) | 297 | WP_005725464.1 | bacteriocin immunity protein | - |
| LPC26_RS10220 | - | 2080321..2080797 (-) | 477 | WP_201785145.1 | thioredoxin family protein | - |
| LPC26_RS10225 | - | 2080851..2081069 (-) | 219 | WP_060461577.1 | TIGR04139 family peptide modification target | - |
| LPC26_RS10230 | - | 2081586..2081732 (-) | 147 | WP_005723821.1 | hypothetical protein | - |
| LPC26_RS10235 | - | 2081742..2081888 (-) | 147 | WP_005727423.1 | hypothetical protein | - |
| LPC26_RS10240 | - | 2082191..2082466 (-) | 276 | WP_005723819.1 | bacteriocin immunity protein | - |
| LPC26_RS10245 | - | 2082488..2082631 (-) | 144 | WP_229265789.1 | hypothetical protein | - |
| LPC26_RS10250 | - | 2082716..2083750 (-) | 1035 | WP_060462509.1 | IS30 family transposase | - |
| LPC26_RS10255 | - | 2084025..2084663 (-) | 639 | WP_005723816.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| LPC26_RS10260 | comA | 2084674..2086836 (-) | 2163 | WP_068813212.1 | peptide cleavage/export ABC transporter | Regulator |
| LPC26_RS10265 | - | 2086817..2087641 (-) | 825 | WP_005718162.1 | LytR/AlgR family response regulator transcription factor | - |
| LPC26_RS10270 | - | 2087645..2089054 (-) | 1410 | WP_229265790.1 | sensor histidine kinase | - |
| LPC26_RS10275 | - | 2089054..2089215 (-) | 162 | WP_005723805.1 | hypothetical protein | - |
| LPC26_RS10280 | - | 2089575..2089781 (-) | 207 | WP_035163480.1 | helix-turn-helix transcriptional regulator | - |
| LPC26_RS10285 | - | 2089778..2090263 (-) | 486 | WP_060462289.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 720 a.a. Molecular weight: 80952.45 Da Isoelectric Point: 9.5103
>NTDB_id=90212 LPC26_RS10260 WP_068813212.1 2084674..2086836(-) (comA) [Lactobacillus crispatus strain KT-11]
MGMLTYKSIYVPQIDETDCGAACLAMILKNYHSQVSIAHLRHIAKTNTEGTTALGLVKTAEKFNMDVQAVKADMSLFNMK
DIQYPFIVHVIKDGGLLHYYVVLKSTKRKIIVADPDPTSGIKKMSKKAFEKEWTGITLFMVPKADFKPVKEKKNNLLSLF
PYMFKQKKLVRNIILAALLMTLISICSSYFVQGLIDTYIPNGTFTTLSVLAIGLLIAYVFNSIFSYGQQFLLNVLGQRLS
IDLNLQYIKHIFELPMEFFTTRKTGEITSRFSDASRIIDALASTVISLFLDLSIVILMGIILAVQNMTLFLITLASLPLY
AIVILGFSKRFERLNNDQMESNAVVSSSIIEDIQGIETIKALNSEQVRYRKIDSQFVDYLKKAFKYSKTEAFQTALKTFI
RLSLNVIILWVGASVVMHNQMSIGELMAFNALLSYFIDPLQNIINLQPTLQAANVAQNRLNEVYLVQSEFKGKTSVNDSH
DLNGDINFSHVDYRYGYGEDVLKDINLTIKDNEKLTIVGMSGSGKSTMVKLLVDFFSPTKGKVTFNGHSTRSINKHVLRS
YVNYVPQTPYIFAGTIKENLLLGSRKNITEKEIEEACQIAEIKNDIEKLPLGFNTQLDENAKILSGGQKQRLTIARALLS
PAKVLIFDEATSGLDTITEKKVVDNLIRLKNKTVIFIAHRLAIAERTDNIVVLNQGQIVEQGNHSELMAKHGYYYDLVKS
MGMLTYKSIYVPQIDETDCGAACLAMILKNYHSQVSIAHLRHIAKTNTEGTTALGLVKTAEKFNMDVQAVKADMSLFNMK
DIQYPFIVHVIKDGGLLHYYVVLKSTKRKIIVADPDPTSGIKKMSKKAFEKEWTGITLFMVPKADFKPVKEKKNNLLSLF
PYMFKQKKLVRNIILAALLMTLISICSSYFVQGLIDTYIPNGTFTTLSVLAIGLLIAYVFNSIFSYGQQFLLNVLGQRLS
IDLNLQYIKHIFELPMEFFTTRKTGEITSRFSDASRIIDALASTVISLFLDLSIVILMGIILAVQNMTLFLITLASLPLY
AIVILGFSKRFERLNNDQMESNAVVSSSIIEDIQGIETIKALNSEQVRYRKIDSQFVDYLKKAFKYSKTEAFQTALKTFI
RLSLNVIILWVGASVVMHNQMSIGELMAFNALLSYFIDPLQNIINLQPTLQAANVAQNRLNEVYLVQSEFKGKTSVNDSH
DLNGDINFSHVDYRYGYGEDVLKDINLTIKDNEKLTIVGMSGSGKSTMVKLLVDFFSPTKGKVTFNGHSTRSINKHVLRS
YVNYVPQTPYIFAGTIKENLLLGSRKNITEKEIEEACQIAEIKNDIEKLPLGFNTQLDENAKILSGGQKQRLTIARALLS
PAKVLIFDEATSGLDTITEKKVVDNLIRLKNKTVIFIAHRLAIAERTDNIVVLNQGQIVEQGNHSELMAKHGYYYDLVKS
Nucleotide
Download Length: 2163 bp
>NTDB_id=90212 LPC26_RS10260 WP_068813212.1 2084674..2086836(-) (comA) [Lactobacillus crispatus strain KT-11]
ATGGGCATGTTAACGTATAAATCAATTTATGTTCCACAAATCGATGAAACAGACTGTGGTGCAGCTTGTTTAGCAATGAT
CTTAAAGAATTATCATTCTCAAGTATCAATAGCACATTTACGTCATATTGCTAAAACCAATACTGAAGGAACTACTGCTT
TAGGATTAGTTAAAACTGCGGAAAAATTCAATATGGATGTTCAAGCGGTAAAAGCAGATATGTCCTTATTCAATATGAAA
GATATTCAATATCCTTTTATTGTTCATGTGATAAAAGATGGAGGATTGTTACATTATTATGTAGTTCTTAAAAGTACTAA
AAGAAAAATAATCGTAGCCGATCCTGATCCTACTAGTGGAATTAAAAAAATGTCCAAAAAGGCGTTTGAAAAAGAGTGGA
CAGGTATTACATTGTTTATGGTGCCTAAGGCAGATTTTAAGCCTGTAAAGGAGAAAAAGAATAATCTATTATCATTATTC
CCTTATATGTTTAAACAGAAAAAGTTAGTTAGAAACATTATTTTAGCTGCTTTGCTGATGACACTGATTAGTATCTGTAG
CTCATATTTTGTACAAGGGTTGATTGATACATATATTCCTAACGGTACATTTACCACGTTATCTGTTTTAGCTATTGGGT
TATTGATTGCATATGTCTTTAACTCAATTTTTTCATATGGTCAGCAATTTTTATTGAATGTTTTGGGGCAGCGGTTATCA
ATCGATCTTAATTTACAATACATTAAGCATATTTTTGAATTACCGATGGAATTTTTTACTACCAGAAAAACTGGTGAGAT
TACTTCTCGTTTTTCTGATGCAAGTAGAATTATAGATGCATTGGCAAGTACGGTGATTTCATTATTCCTTGATCTTTCAA
TTGTAATTTTAATGGGTATAATTTTGGCGGTTCAAAACATGACATTGTTTTTGATTACGCTAGCTTCATTACCACTCTAT
GCTATTGTTATTCTCGGCTTTTCAAAAAGGTTTGAAAGATTAAATAATGACCAGATGGAAAGTAATGCGGTAGTTAGTTC
ATCAATTATTGAAGATATTCAAGGAATTGAGACGATTAAAGCATTAAACAGTGAACAAGTACGTTATCGAAAAATTGATA
GTCAGTTTGTTGATTATTTAAAAAAAGCTTTTAAGTATAGCAAAACAGAAGCTTTTCAAACTGCTTTGAAAACTTTTATT
AGATTATCACTGAATGTCATTATTCTTTGGGTGGGGGCAAGTGTTGTAATGCATAATCAGATGTCTATTGGTGAATTGAT
GGCATTTAATGCATTATTATCATATTTTATTGATCCATTACAAAATATTATTAACTTGCAACCTACACTTCAAGCTGCAA
ATGTAGCTCAGAATCGTTTAAATGAAGTTTATTTAGTTCAAAGTGAATTTAAGGGCAAAACTTCAGTTAATGATAGTCAT
GATTTAAATGGAGACATTAATTTTTCACATGTCGATTATCGTTATGGATATGGTGAAGATGTCTTAAAAGATATTAATTT
GACGATCAAAGATAATGAGAAATTAACTATTGTGGGAATGAGTGGATCAGGTAAGTCAACTATGGTTAAATTGTTGGTTG
ATTTTTTCAGTCCCACAAAAGGAAAAGTAACTTTTAATGGTCATTCGACTAGAAGTATAAATAAGCATGTTTTACGCTCA
TATGTGAATTATGTGCCACAAACTCCATATATTTTTGCAGGTACCATTAAAGAGAATCTTTTGTTGGGAAGTCGTAAGAA
TATAACTGAAAAAGAGATAGAAGAAGCTTGCCAAATCGCGGAGATAAAGAATGACATTGAAAAATTGCCATTAGGATTTA
ATACACAATTAGATGAAAATGCTAAGATTTTGTCAGGTGGTCAGAAGCAAAGATTAACAATTGCTAGGGCCTTACTTTCA
CCTGCTAAGGTATTGATTTTTGATGAAGCAACAAGTGGGCTTGATACAATTACTGAGAAAAAAGTGGTTGATAATTTAAT
TAGGTTAAAGAATAAAACTGTTATATTTATTGCGCATCGTTTAGCTATTGCTGAAAGAACTGACAATATTGTGGTATTGA
ATCAGGGTCAAATTGTAGAACAAGGTAATCACAGTGAATTAATGGCTAAACATGGGTATTATTATGATTTGGTGAAAAGC
TAG
ATGGGCATGTTAACGTATAAATCAATTTATGTTCCACAAATCGATGAAACAGACTGTGGTGCAGCTTGTTTAGCAATGAT
CTTAAAGAATTATCATTCTCAAGTATCAATAGCACATTTACGTCATATTGCTAAAACCAATACTGAAGGAACTACTGCTT
TAGGATTAGTTAAAACTGCGGAAAAATTCAATATGGATGTTCAAGCGGTAAAAGCAGATATGTCCTTATTCAATATGAAA
GATATTCAATATCCTTTTATTGTTCATGTGATAAAAGATGGAGGATTGTTACATTATTATGTAGTTCTTAAAAGTACTAA
AAGAAAAATAATCGTAGCCGATCCTGATCCTACTAGTGGAATTAAAAAAATGTCCAAAAAGGCGTTTGAAAAAGAGTGGA
CAGGTATTACATTGTTTATGGTGCCTAAGGCAGATTTTAAGCCTGTAAAGGAGAAAAAGAATAATCTATTATCATTATTC
CCTTATATGTTTAAACAGAAAAAGTTAGTTAGAAACATTATTTTAGCTGCTTTGCTGATGACACTGATTAGTATCTGTAG
CTCATATTTTGTACAAGGGTTGATTGATACATATATTCCTAACGGTACATTTACCACGTTATCTGTTTTAGCTATTGGGT
TATTGATTGCATATGTCTTTAACTCAATTTTTTCATATGGTCAGCAATTTTTATTGAATGTTTTGGGGCAGCGGTTATCA
ATCGATCTTAATTTACAATACATTAAGCATATTTTTGAATTACCGATGGAATTTTTTACTACCAGAAAAACTGGTGAGAT
TACTTCTCGTTTTTCTGATGCAAGTAGAATTATAGATGCATTGGCAAGTACGGTGATTTCATTATTCCTTGATCTTTCAA
TTGTAATTTTAATGGGTATAATTTTGGCGGTTCAAAACATGACATTGTTTTTGATTACGCTAGCTTCATTACCACTCTAT
GCTATTGTTATTCTCGGCTTTTCAAAAAGGTTTGAAAGATTAAATAATGACCAGATGGAAAGTAATGCGGTAGTTAGTTC
ATCAATTATTGAAGATATTCAAGGAATTGAGACGATTAAAGCATTAAACAGTGAACAAGTACGTTATCGAAAAATTGATA
GTCAGTTTGTTGATTATTTAAAAAAAGCTTTTAAGTATAGCAAAACAGAAGCTTTTCAAACTGCTTTGAAAACTTTTATT
AGATTATCACTGAATGTCATTATTCTTTGGGTGGGGGCAAGTGTTGTAATGCATAATCAGATGTCTATTGGTGAATTGAT
GGCATTTAATGCATTATTATCATATTTTATTGATCCATTACAAAATATTATTAACTTGCAACCTACACTTCAAGCTGCAA
ATGTAGCTCAGAATCGTTTAAATGAAGTTTATTTAGTTCAAAGTGAATTTAAGGGCAAAACTTCAGTTAATGATAGTCAT
GATTTAAATGGAGACATTAATTTTTCACATGTCGATTATCGTTATGGATATGGTGAAGATGTCTTAAAAGATATTAATTT
GACGATCAAAGATAATGAGAAATTAACTATTGTGGGAATGAGTGGATCAGGTAAGTCAACTATGGTTAAATTGTTGGTTG
ATTTTTTCAGTCCCACAAAAGGAAAAGTAACTTTTAATGGTCATTCGACTAGAAGTATAAATAAGCATGTTTTACGCTCA
TATGTGAATTATGTGCCACAAACTCCATATATTTTTGCAGGTACCATTAAAGAGAATCTTTTGTTGGGAAGTCGTAAGAA
TATAACTGAAAAAGAGATAGAAGAAGCTTGCCAAATCGCGGAGATAAAGAATGACATTGAAAAATTGCCATTAGGATTTA
ATACACAATTAGATGAAAATGCTAAGATTTTGTCAGGTGGTCAGAAGCAAAGATTAACAATTGCTAGGGCCTTACTTTCA
CCTGCTAAGGTATTGATTTTTGATGAAGCAACAAGTGGGCTTGATACAATTACTGAGAAAAAAGTGGTTGATAATTTAAT
TAGGTTAAAGAATAAAACTGTTATATTTATTGCGCATCGTTTAGCTATTGCTGAAAGAACTGACAATATTGTGGTATTGA
ATCAGGGTCAAATTGTAGAACAAGGTAATCACAGTGAATTAATGGCTAAACATGGGTATTATTATGATTTGGTGAAAAGC
TAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis NCTC 12261 |
55.602 |
99.167 |
0.551 |
| comA | Streptococcus pneumoniae Rx1 |
55.462 |
99.167 |
0.55 |
| comA | Streptococcus pneumoniae D39 |
55.462 |
99.167 |
0.55 |
| comA | Streptococcus pneumoniae R6 |
55.462 |
99.167 |
0.55 |
| comA | Streptococcus pneumoniae TIGR4 |
55.322 |
99.167 |
0.549 |
| comA | Streptococcus mitis SK321 |
55.182 |
99.167 |
0.547 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
54.342 |
99.167 |
0.539 |
| comA/nlmT | Streptococcus mutans UA159 |
54.173 |
98.194 |
0.532 |