Detailed information NTG0899407

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: R6U80_RS09610
• Genome accession: NZ_CP137623
• Coordinates: 1975182..1977392 (-)
• Length: 736 a.a.
• NCBI ID: WP_313791935.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain NCK401
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1970182..1982392

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6U80_RS09580 (R6U80_09580)	atpA	1970224..1971726 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
R6U80_RS09585 (R6U80_09585)	-	1971913..1972440 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
R6U80_RS09590 (R6U80_09590)	atpF	1972442..1972948 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
R6U80_RS09595 (R6U80_09595)	atpB	1972963..1973676 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
R6U80_RS09600 (R6U80_09600)	-	1973721..1973936 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
R6U80_RS09605 (R6U80_09605)	-	1974121..1974897 (-)	777	WP_023188533.1	alpha/beta hydrolase family protein	-
R6U80_RS09610 (R6U80_09610)	comEC	1975182..1977392 (-)	2211	WP_313791935.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R6U80_RS09615 (R6U80_09615)	comEA	1977373..1978020 (-)	648	WP_010906131.1	ComEA family DNA-binding protein	Machinery gene
R6U80_RS09620 (R6U80_09620)	-	1978080..1979441 (-)	1362	WP_313791934.1	ABC transporter permease	-
R6U80_RS09625 (R6U80_09625)	-	1979438..1980370 (-)	933	WP_313791933.1	ABC transporter ATP-binding protein	-
R6U80_RS09630 (R6U80_09630)	-	1980476..1980874 (-)	399	WP_023188528.1	hypothetical protein	-
R6U80_RS09635 (R6U80_09635)	-	1980978..1981541 (-)	564	WP_251900925.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84657.19 Da
• Isoelectric Point: 9.5681

>NTDB_id=899407 R6U80_RS09610 WP_313791935.1 1975182..1977392(-) (comEC) [Lactococcus lactis strain NCK401]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLLCLILFIFSSLLASYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERDQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQDI
YRQITIDKINKIVLNDTFDLRVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSILPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINYIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLNDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTEKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNSDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=899407 R6U80_RS09610 WP_313791935.1 1975182..1977392(-) (comEC) [Lactococcus lactis strain NCK401]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTACTTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTCATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGACCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGGATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCGTGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTATTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATTATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAAATGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGAAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACTCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-171)

• Competence protein (Competence) (206-445)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.359	100	0.764
comEC/celB	Streptococcus mitis SK321	44.624	100	0.451
comEC/celB	Streptococcus mitis NCTC 12261	44.415	100	0.448
comEC/celB	Streptococcus pneumoniae TIGR4	43.414	100	0.439
comEC/celB	Streptococcus pneumoniae Rx1	43.011	100	0.435
comEC/celB	Streptococcus pneumoniae D39	43.011	100	0.435
comEC/celB	Streptococcus pneumoniae R6	43.011	100	0.435