Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   R5H38_RS08200 Genome accession   NZ_CP137602
Coordinates   1595780..1596496 (-) Length   238 a.a.
NCBI ID   WP_130554705.1    Uniprot ID   -
Organism   Streptococcus parasuis strain 221006     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1590780..1601496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5H38_RS08180 - 1591144..1592370 (-) 1227 WP_277837441.1 cysteine desulfurase -
  R5H38_RS08185 sufD 1592375..1593637 (-) 1263 WP_217374211.1 Fe-S cluster assembly protein SufD -
  R5H38_RS08190 sufC 1593654..1594427 (-) 774 WP_171989104.1 Fe-S cluster assembly ATPase SufC -
  R5H38_RS08195 - 1594599..1595783 (-) 1185 WP_217374212.1 glycosyltransferase family 4 protein -
  R5H38_RS08200 mecA 1595780..1596496 (-) 717 WP_130554705.1 adaptor protein MecA Regulator
  R5H38_RS08205 - 1596702..1597541 (-) 840 WP_274504947.1 undecaprenyl-diphosphate phosphatase -
  R5H38_RS08210 - 1597817..1599379 (+) 1563 WP_217374214.1 ABC transporter substrate-binding protein/permease -
  R5H38_RS08215 - 1599372..1600115 (+) 744 WP_130554708.1 amino acid ABC transporter ATP-binding protein -
  R5H38_RS08220 - 1600225..1600434 (-) 210 WP_024391394.1 hypothetical protein -
  R5H38_RS08225 - 1600524..1601426 (-) 903 WP_274504258.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27881.56 Da        Isoelectric Point: 4.1340

>NTDB_id=899252 R5H38_RS08200 WP_130554705.1 1595780..1596496(-) (mecA) [Streptococcus parasuis strain 221006]
MKVKQISDSTLKITIQLEDLEERGMEIADFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDKVDIFVTKSEM
DQSLNFDEFTDLSELGDVSRMTPDELLKSLERTVRERSTHDSKAVRLLEDAEKEDSDEYQEQYIYYILEFPALIDAVNFV
QTVDYPVEESELYKVEQTYYMTVLINVAERSKQYPEYILSRMLEFTNDTKLTRPFLQEHGILMLGNGAIDELKKVQTV

Nucleotide


Download         Length: 717 bp        

>NTDB_id=899252 R5H38_RS08200 WP_130554705.1 1595780..1596496(-) (mecA) [Streptococcus parasuis strain 221006]
ATGAAAGTAAAACAAATAAGTGATTCGACTCTAAAAATCACTATCCAATTAGAAGATTTAGAGGAGCGCGGGATGGAAAT
TGCGGATTTCCTTATCCCTCAAGAAAAGACGGAAGAGTTTTTTTATACAGTATTGGATGAATTGGATTTGCCAATGACTT
TCCGAGAAAGTGGAATGCTTAGTTTTAGAGTTACTCCAAAACCGGATAAAGTGGATATTTTTGTCACAAAATCTGAAATG
GATCAAAGTTTAAATTTTGATGAATTTACAGATTTATCGGAATTAGGCGATGTATCAAGAATGACTCCAGATGAATTGCT
GAAAAGTTTAGAACGTACAGTTCGTGAACGAAGCACGCATGACTCAAAAGCAGTTCGTCTATTAGAAGATGCTGAAAAAG
AAGATAGTGATGAATACCAAGAACAGTATATTTACTATATCTTAGAATTTCCTGCTTTGATTGATGCGGTAAATTTTGTT
CAAACAGTGGATTATCCAGTTGAAGAATCTGAGCTCTACAAGGTGGAACAAACCTATTATATGACAGTATTGATTAATGT
TGCAGAGCGTTCAAAGCAGTATCCGGAGTATATTCTATCTCGCATGCTTGAATTTACAAACGATACCAAATTGACACGAC
CATTTCTTCAAGAGCACGGAATCTTGATGTTGGGAAATGGGGCCATTGATGAGTTGAAAAAGGTGCAAACGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

49.18

100

0.504
  mecA Streptococcus pneumoniae D39

49.18

100

0.504
  mecA Streptococcus pneumoniae R6

49.18

100

0.504
  mecA Streptococcus pneumoniae TIGR4

49.18

100

0.504
  mecA Streptococcus mutans UA159

47.951

100

0.492
  mecA Streptococcus thermophilus LMD-9

45.714

100

0.471
  mecA Streptococcus thermophilus LMG 18311

45.306

100

0.466