Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   R5H38_RS04440 Genome accession   NZ_CP137602
Coordinates   864007..864678 (+) Length   223 a.a.
NCBI ID   WP_130555646.1    Uniprot ID   A0A4Q8KZI7
Organism   Streptococcus parasuis strain 221006     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 859007..869678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5H38_RS10290 - 860230..861387 (+) 1158 WP_412080678.1 LTA synthase family protein -
  R5H38_RS04430 - 861384..862859 (+) 1476 WP_274504852.1 glucosyltransferase domain-containing protein -
  R5H38_RS04435 - 862871..863803 (+) 933 WP_274504853.1 glycosyltransferase family 2 protein -
  R5H38_RS04440 ciaR 864007..864678 (+) 672 WP_130555646.1 response regulator transcription factor Regulator
  R5H38_RS04445 ciaH 864671..866044 (+) 1374 WP_318150943.1 HAMP domain-containing sensor histidine kinase Regulator
  R5H38_RS04450 - 866131..867348 (+) 1218 WP_318150944.1 transglutaminase domain-containing protein -
  R5H38_RS04455 rpsT 867382..867630 (-) 249 WP_277843602.1 30S ribosomal protein S20 -
  R5H38_RS04460 coaA 867689..868609 (-) 921 WP_277843603.1 type I pantothenate kinase -
  R5H38_RS04465 - 868685..869275 (+) 591 WP_217375057.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25212.80 Da        Isoelectric Point: 4.2408

>NTDB_id=899232 R5H38_RS04440 WP_130555646.1 864007..864678(+) (ciaR) [Streptococcus parasuis strain 221006]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPDKDGFQVLRELREKGVSTPVLITTA
KEGLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNTTTVNGQEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGENLQTLRSVGYILKNV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=899232 R5H38_RS04440 WP_130555646.1 864007..864678(+) (ciaR) [Streptococcus parasuis strain 221006]
ATGATTAAAATATTATTGGTCGAAGATGATTTAAGTTTATCCAATTCAGTCTTTGATTTTTTAGATGATTTTGCAGACGT
TATGCAAGTTTTTGATGGTGAAGAAGGTATTTACGAAGCGGAAACAGGGGTTTATGATTTAATTCTTTTAGATTTAATGT
TACCTGATAAAGATGGTTTTCAAGTATTAAGAGAATTGCGTGAAAAAGGGGTCTCAACTCCTGTTCTGATTACGACAGCC
AAGGAAGGCCTAGAGGATAAAGGACATGGGTTTGAATTGGGTGCAGATGACTATCTCACAAAACCATTCTATTTAGAAGA
ACTCAAAATGCGTATTCAAGCCTTGTTAAAACGAGCAGGGAAGTTCAATGAAAATACTCTAACGTACGGAGATGTTACTG
TCGACTTATCTACAAATACTACGACAGTCAATGGTCAAGAAGTAGAATTGTTAGGGAAAGAATTCGACTTGTTGGTATAT
TTCTTACAGAACCAGAATGTGATTTTACCTAAAACACAGATTTTTGATCGTATTTGGGGATTTGATAGTGATACAACCAT
TTCAGTTGTTGAAGTTTACGTATCGAAAGTAAGGAAAAAATTGAAAGGAACTGCATTTGGAGAAAATCTTCAAACTCTTC
GTAGTGTCGGTTACATTTTGAAAAATGTCTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Q8KZI7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

88.341

100

0.883
  ciaR Streptococcus pneumoniae Rx1

87.892

100

0.879
  ciaR Streptococcus pneumoniae D39

87.892

100

0.879
  ciaR Streptococcus pneumoniae R6

87.892

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.892

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.611

100

0.381