Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   R5H38_RS04445 Genome accession   NZ_CP137602
Coordinates   864671..866044 (+) Length   457 a.a.
NCBI ID   WP_318150943.1    Uniprot ID   -
Organism   Streptococcus parasuis strain 221006     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 859671..871044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5H38_RS10290 - 860230..861387 (+) 1158 WP_412080678.1 LTA synthase family protein -
  R5H38_RS04430 - 861384..862859 (+) 1476 WP_274504852.1 glucosyltransferase domain-containing protein -
  R5H38_RS04435 - 862871..863803 (+) 933 WP_274504853.1 glycosyltransferase family 2 protein -
  R5H38_RS04440 ciaR 864007..864678 (+) 672 WP_130555646.1 response regulator transcription factor Regulator
  R5H38_RS04445 ciaH 864671..866044 (+) 1374 WP_318150943.1 HAMP domain-containing sensor histidine kinase Regulator
  R5H38_RS04450 - 866131..867348 (+) 1218 WP_318150944.1 transglutaminase domain-containing protein -
  R5H38_RS04455 rpsT 867382..867630 (-) 249 WP_277843602.1 30S ribosomal protein S20 -
  R5H38_RS04460 coaA 867689..868609 (-) 921 WP_277843603.1 type I pantothenate kinase -
  R5H38_RS04465 - 868685..869275 (+) 591 WP_217375057.1 class I SAM-dependent methyltransferase -
  R5H38_RS04470 - 869272..870549 (+) 1278 WP_318150945.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51574.71 Da        Isoelectric Point: 5.1184

>NTDB_id=899233 R5H38_RS04445 WP_318150943.1 864671..866044(+) (ciaH) [Streptococcus parasuis strain 221006]
MSKRFKKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNIADESDSAESNSDTQNSPKNQKDDQLKLGYNTHVLLYSKDGQVVNPDNFTGLSDLSLDKKNLGEIKEVTVDSTFGSSE
DYRYVTIELAPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISIFASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLAVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIVEVPPSYFDEI
FENYMMIADENGKTVTVNNLIDQPIRTDKVLVKQLLTILFDNAMKYTEEDGAIQVTANIKDKLVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=899233 R5H38_RS04445 WP_318150943.1 864671..866044(+) (ciaH) [Streptococcus parasuis strain 221006]
ATGTCTAAGCGATTTAAAAAAATCATTTCAACAGATAAATTTTCCTTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACCGCCATTATCTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCTGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAT
GGAAATATTGCTGATGAAAGTGATTCTGCTGAATCTAATTCAGATACACAAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTACAATACACATGTATTGCTTTATTCAAAAGATGGTCAAGTAGTTAACCCTGATAACTTTACCGGTT
TGTCTGATTTATCCTTAGACAAGAAAAATTTAGGCGAAATAAAGGAAGTAACGGTTGATTCTACATTCGGGAGTTCAGAA
GATTATCGTTATGTTACTATTGAATTGGCGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCCATTGAGACGTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTTGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTGATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTTTAGCTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTTTGGAAAGTAGTGAGAGTATAGGATCAAGCCTAGAGGAAGTTCGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATAGTTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTGAGAATTACATGATGATTGCAGATGAAAATGGTAAAACAGTCACGGTTAATAATTTGATTGATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGAAGATGGCGCTATAC
AAGTGACAGCCAATATCAAAGATAAGTTAGTTTACTTTACGGTAGCAGACAATGGATTGGGTATCAGTGATAGTGATAAA
AAGAAAATTTTCGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTCGGTTTATCCTT
AGCCTTACAAATTTCCAATAGTTTGAAAGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTACCGAGATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae D39

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae R6

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae TIGR4

51.096

99.781

0.51
  ciaH Streptococcus mutans UA159

50.11

99.125

0.497