Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   R5H38_RS00320 Genome accession   NZ_CP137602
Coordinates   54150..55502 (+) Length   450 a.a.
NCBI ID   WP_318150686.1    Uniprot ID   -
Organism   Streptococcus parasuis strain 221006     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 49150..60502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5H38_RS00305 - 50220..50813 (+) 594 WP_318150683.1 MerR family transcriptional regulator -
  R5H38_RS00310 - 51102..51488 (+) 387 WP_318150684.1 hypothetical protein -
  R5H38_RS00315 comA 51985..54138 (+) 2154 WP_318150685.1 peptide cleavage/export ABC transporter ComA Regulator
  R5H38_RS00320 comB 54150..55502 (+) 1353 WP_318150686.1 bacteriocin secretion accessory protein Regulator
  R5H38_RS00325 - 55891..56070 (+) 180 WP_024392853.1 hypothetical protein -
  R5H38_RS00330 - 56071..56271 (+) 201 WP_239604410.1 hypothetical protein -
  R5H38_RS00335 - 56288..56479 (+) 192 WP_024392851.1 hypothetical protein -
  R5H38_RS00340 - 56840..57709 (-) 870 WP_289646198.1 cysteine ABC transporter substrate-binding protein -
  R5H38_RS00345 - 57722..58468 (-) 747 WP_217374488.1 amino acid ABC transporter ATP-binding protein -
  R5H38_RS00350 - 58473..59150 (-) 678 WP_318150687.1 amino acid ABC transporter permease -
  R5H38_RS00355 - 59131..59790 (-) 660 WP_277844343.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50731.34 Da        Isoelectric Point: 4.8239

>NTDB_id=899211 R5H38_RS00320 WP_318150686.1 54150..55502(+) (comB) [Streptococcus parasuis strain 221006]
MDHHLLESAEFYNRRYHNAASRVIIPSCILFLFLILFSIVAKKEMTISTRATVEPVQRLAQIHSISNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKIKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCNQLETLASTIDQQN
ATIASQNQVAKQSQLELEKVMHQTEKALADYRELKSAIQSDGVIDEENVGYSIYAQYQLAQSEDAVASQESFVAQIDNQI
SQVETQLASYKLQYAGAGVQQSYTNSLDSQSASLKAQYLTKVGQEMTMLSSQLRDLEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIAYVYPVLMEAKKMKITAYIPSKDIASISLKDNIQFSIQGKGVKRLALQSNISEIASTANQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=899211 R5H38_RS00320 WP_318150686.1 54150..55502(+) (comB) [Streptococcus parasuis strain 221006]
ATGGACCATCATCTGTTAGAAAGTGCAGAATTTTACAACAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTATATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTGCTAAAAAAGAAATGACCATTTCAACAAGAGCAACCGTAG
AACCTGTACAACGATTAGCACAGATTCACTCAATCAGTAATCATCAGATTCTGAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTAGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGATCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCAATCAATTAGAAACATTGGCAAGTACGATTGACCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGTTGCAAAACAATCACAATTGGAATTGGAAAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAATCGGCCATTCAGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGTTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCGTCGCTCAAATCGATAATCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCCGGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCGTTGAAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCATGTTGTCTTCTCAATTAA
GAGACCTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGATAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCATATGTTTATCCAGTTCTAATGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CAATACAAGGGAAGGGAGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCAATCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

49.443

99.778

0.493
  comB Streptococcus pneumoniae D39

47.333

100

0.473
  comB Streptococcus pneumoniae R6

47.333

100

0.473
  comB Streptococcus pneumoniae Rx1

47.333

100

0.473
  comB Streptococcus pneumoniae TIGR4

46.889

100

0.469
  comB Streptococcus mitis NCTC 12261

46

100

0.46
  comB Streptococcus mitis SK321

45.778

100

0.458