Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   ABD408_RS00610 Genome accession   NZ_CP155735
Coordinates   97866..98294 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 4958/15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92866..103294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABD408_RS00590 (ABD408_00580) - 95197..95562 (+) 366 WP_002986560.1 DUF1033 family protein -
  ABD408_RS00595 (ABD408_00585) comGA 95655..96593 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  ABD408_RS00600 (ABD408_00590) comGB 96529..97563 (+) 1035 WP_229363300.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABD408_RS00605 (ABD408_00595) comGC 97565..97891 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  ABD408_RS00610 (ABD408_00600) comGD 97866..98294 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABD408_RS00615 (ABD408_00605) comGE 98251..98535 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABD408_RS00620 (ABD408_00610) comGF 98528..98962 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABD408_RS00625 (ABD408_00615) comGG 98946..99272 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  ABD408_RS00630 (ABD408_00620) comGH 99370..100323 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  ABD408_RS00635 (ABD408_00625) - 100382..101578 (+) 1197 WP_023612537.1 acetate kinase -
  ABD408_RS00640 (ABD408_00630) - 101765..102073 (+) 309 WP_032465606.1 hypothetical protein -
  ABD408_RS00645 (ABD408_00635) proC 102156..102926 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=898092 ABD408_RS00610 WP_002986548.1 97866..98294(+) (comGD) [Streptococcus pyogenes strain 4958/15]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=898092 ABD408_RS00610 WP_002986548.1 97866..98294(+) (comGD) [Streptococcus pyogenes strain 4958/15]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366