Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ABD408_RS00615 Genome accession   NZ_CP155735
Coordinates   98251..98535 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain 4958/15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 93251..103535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABD408_RS00590 (ABD408_00580) - 95197..95562 (+) 366 WP_002986560.1 DUF1033 family protein -
  ABD408_RS00595 (ABD408_00585) comGA 95655..96593 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  ABD408_RS00600 (ABD408_00590) comGB 96529..97563 (+) 1035 WP_229363300.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABD408_RS00605 (ABD408_00595) comGC 97565..97891 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  ABD408_RS00610 (ABD408_00600) comGD 97866..98294 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABD408_RS00615 (ABD408_00605) comGE 98251..98535 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABD408_RS00620 (ABD408_00610) comGF 98528..98962 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABD408_RS00625 (ABD408_00615) comGG 98946..99272 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  ABD408_RS00630 (ABD408_00620) comGH 99370..100323 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  ABD408_RS00635 (ABD408_00625) - 100382..101578 (+) 1197 WP_023612537.1 acetate kinase -
  ABD408_RS00640 (ABD408_00630) - 101765..102073 (+) 309 WP_032465606.1 hypothetical protein -
  ABD408_RS00645 (ABD408_00635) proC 102156..102926 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=898093 ABD408_RS00615 WP_002987779.1 98251..98535(+) (comGE) [Streptococcus pyogenes strain 4958/15]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=898093 ABD408_RS00615 WP_002987779.1 98251..98535(+) (comGE) [Streptococcus pyogenes strain 4958/15]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383