Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ABC812_RS06250 Genome accession   NZ_CP155537
Coordinates   1237455..1238096 (-) Length   213 a.a.
NCBI ID   WP_000151458.1    Uniprot ID   Q8DPF9
Organism   Streptococcus pneumoniae strain DP1322     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1232455..1243096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC812_RS06220 (ABC812_06215) - 1232569..1232811 (+) 243 WP_000710764.1 type B 50S ribosomal protein L31 -
  ABC812_RS06225 (ABC812_06220) - 1232868..1233446 (-) 579 WP_000252103.1 hypothetical protein -
  ABC812_RS06230 (ABC812_06225) efeB 1233421..1234434 (-) 1014 Protein_1230 iron uptake transporter deferrochelatase/peroxidase subunit -
  ABC812_RS06235 (ABC812_06230) - 1234437..1235018 (-) 582 Protein_1231 winged helix-turn-helix domain-containing protein -
  ABC812_RS06240 (ABC812_06235) gdhA 1235430..1236776 (+) 1347 WP_000199534.1 NADP-specific glutamate dehydrogenase -
  ABC812_RS06245 (ABC812_06240) - 1237272..1237442 (-) 171 WP_000711943.1 hypothetical protein -
  ABC812_RS06250 (ABC812_06245) comA 1237455..1238096 (-) 642 WP_000151458.1 ATP-binding cassette domain-containing protein Regulator
  ABC812_RS06255 (ABC812_06250) - 1238221..1238407 (-) 187 Protein_1235 hypothetical protein -
  ABC812_RS06260 (ABC812_06255) - 1238368..1238805 (+) 438 WP_001856204.1 hypothetical protein -
  ABC812_RS06265 (ABC812_06260) - 1238807..1238875 (+) 69 WP_225208679.1 hypothetical protein -
  ABC812_RS06270 (ABC812_06265) - 1239096..1239290 (-) 195 Protein_1238 ROK family protein -
  ABC812_RS06275 (ABC812_06270) - 1239317..1240234 (-) 918 Protein_1239 dihydrodipicolinate synthase family protein -
  ABC812_RS06280 (ABC812_06275) - 1240266..1240673 (-) 408 WP_000216067.1 cytidine deaminase -
  ABC812_RS06285 (ABC812_06280) - 1240961..1241449 (-) 489 WP_000872894.1 phosphatidylglycerophosphatase A -
  ABC812_RS06290 (ABC812_06285) - 1241454..1242677 (-) 1224 WP_363783108.1 hypothetical protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23486.26 Da        Isoelectric Point: 9.2387

>NTDB_id=897289 ABC812_RS06250 WP_000151458.1 1237455..1238096(-) (comA) [Streptococcus pneumoniae strain DP1322]
MTIEPGQRIALVGQSGSGKSTLSKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEV
TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK

Nucleotide


Download         Length: 642 bp        

>NTDB_id=897289 ABC812_RS06250 WP_000151458.1 1237455..1238096(-) (comA) [Streptococcus pneumoniae strain DP1322]
TTGACTATTGAGCCAGGACAGAGAATTGCACTAGTCGGTCAATCGGGGTCAGGAAAAAGTACGTTATCAAAAATACCATC
AGGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC
AAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGCACGAAGTT
ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC
TATCATCTCAGAGATGGGTTCAAATATTTCAGGTGGTCAAAGACAACGGATAGCACTGGCACGTGCATTAATAAATAATC
CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATATAAAAAGT
CAGGGCTGTACTCAAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTGTTGTAATGAAAGGTGG
TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAAT
GA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DPF9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

43.81

98.592

0.432
  comA Streptococcus mitis SK321

43.333

98.592

0.427
  comA Streptococcus gordonii str. Challis substr. CH1

42.453

99.531

0.423
  comA/nlmT Streptococcus mutans UA159

42.453

99.531

0.423
  comA Streptococcus pneumoniae R6

42.381

98.592

0.418
  comA Streptococcus pneumoniae Rx1

42.381

98.592

0.418
  comA Streptococcus pneumoniae D39

42.381

98.592

0.418
  comA Streptococcus pneumoniae TIGR4

41.429

98.592

0.408
  rcrQ Streptococcus mutans UA159

36.62

100

0.366