Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   R4705_RS05705 Genome accession   NZ_CP137115
Coordinates   1077776..1079125 (+) Length   449 a.a.
NCBI ID   WP_000801618.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20614-6     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1072776..1084125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS05675 plsX 1072895..1073887 (+) 993 WP_000717458.1 phosphate acyltransferase PlsX -
  R4705_RS05680 - 1073893..1074126 (+) 234 WP_000136447.1 acyl carrier protein -
  R4705_RS05685 - 1074163..1074462 (+) 300 Protein_1068 transposase family protein -
  R4705_RS05690 blpU 1074665..1074895 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  R4705_RS05695 - 1074898..1075023 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  R4705_RS05700 comA 1075610..1077763 (+) 2154 WP_000668277.1 peptide cleavage/export ABC transporter ComA Regulator
  R4705_RS05705 comB 1077776..1079125 (+) 1350 WP_000801618.1 competence pheromone export protein ComB Regulator
  R4705_RS05710 purC 1079295..1080002 (+) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  R4705_RS05715 - 1080004..1080147 (+) 144 WP_050167432.1 hypothetical protein -
  R4705_RS05720 - 1080204..1083929 (+) 3726 WP_000361179.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49615.49 Da        Isoelectric Point: 5.3895

>NTDB_id=896278 R4705_RS05705 WP_000801618.1 1077776..1079125(+) (comB) [Streptococcus pneumoniae strain 20614-6]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=896278 R4705_RS05705 WP_000801618.1 1077776..1079125(+) (comB) [Streptococcus pneumoniae strain 20614-6]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTTCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

99.109

100

0.991
  comB Streptococcus pneumoniae Rx1

98.886

100

0.989
  comB Streptococcus pneumoniae D39

98.886

100

0.989
  comB Streptococcus pneumoniae R6

98.886

100

0.989
  comB Streptococcus mitis SK321

95.1

100

0.951
  comB Streptococcus mitis NCTC 12261

94.655

100

0.947
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555