Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4707_RS05625 Genome accession   NZ_CP137113
Coordinates   1054781..1055443 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain ZGX     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1049781..1060443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS05600 - 1049931..1050197 (-) 267 WP_001278167.1 Veg family protein -
  R4707_RS05605 dnaB 1050199..1051551 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R4707_RS05610 rplI 1051595..1052047 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4707_RS05615 - 1052044..1054017 (-) 1974 WP_081543126.1 DHH family phosphoesterase -
  R4707_RS05620 hpf 1054153..1054701 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4707_RS05625 comFC/cflB 1054781..1055443 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  R4707_RS05630 comFA/cflA 1055440..1056738 (-) 1299 WP_081543128.1 DEAD/DEAH box helicase Machinery gene
  R4707_RS05635 - 1056794..1057429 (+) 636 WP_050072350.1 YigZ family protein -
  R4707_RS05640 cysK 1057714..1058634 (+) 921 WP_000029866.1 cysteine synthase A -
  R4707_RS05645 - 1058873..1059223 (-) 351 Protein_1068 IS66 family transposase -
  R4707_RS05650 - 1059223..1059515 (+) 293 Protein_1069 transposase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=896114 R4707_RS05625 WP_000649971.1 1054781..1055443(-) (comFC/cflB) [Streptococcus pneumoniae strain ZGX]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=896114 R4707_RS05625 WP_000649971.1 1054781..1055443(-) (comFC/cflB) [Streptococcus pneumoniae strain ZGX]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914