Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   R4707_RS05630 Genome accession   NZ_CP137113
Coordinates   1055440..1056738 (-) Length   432 a.a.
NCBI ID   WP_081543128.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ZGX     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1050440..1061738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS05610 rplI 1051595..1052047 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4707_RS05615 - 1052044..1054017 (-) 1974 WP_081543126.1 DHH family phosphoesterase -
  R4707_RS05620 hpf 1054153..1054701 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4707_RS05625 comFC/cflB 1054781..1055443 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  R4707_RS05630 comFA/cflA 1055440..1056738 (-) 1299 WP_081543128.1 DEAD/DEAH box helicase Machinery gene
  R4707_RS05635 - 1056794..1057429 (+) 636 WP_050072350.1 YigZ family protein -
  R4707_RS05640 cysK 1057714..1058634 (+) 921 WP_000029866.1 cysteine synthase A -
  R4707_RS05645 - 1058873..1059223 (-) 351 Protein_1068 IS66 family transposase -
  R4707_RS05650 - 1059223..1059515 (+) 293 Protein_1069 transposase -
  R4707_RS05655 - 1059940..1061286 (+) 1347 WP_001841633.1 IS1380-like element ISSpn5 family transposase -
  R4707_RS05660 tnpB 1061427..1061687 (-) 261 WP_277776461.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49551.48 Da        Isoelectric Point: 8.2050

>NTDB_id=896115 R4707_RS05630 WP_081543128.1 1055440..1056738(-) (comFA/cflA) [Streptococcus pneumoniae strain ZGX]
MKVNLDYLGCLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKENGLRIFLTATST
NELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSDFNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEI
LQEQFPNEKIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=896115 R4707_RS05630 WP_081543128.1 1055440..1056738(-) (comFA/cflA) [Streptococcus pneumoniae strain ZGX]
ATGAAAGTAAATTTAGATTATCTCGGTTGTTTATTTACTGAGAATGAATTAACAGAAGAAGAACGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAGGGGAAACTTTTCTGTCAACGTTGTAATAGCACTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGAGAGTGCTTGCTGATGAAGCGAGTCAGAAGTGATCAAACTTTATACTATTTTCCGCAG
GAGGATTTTCCGAAGCAAGATGTTCTCAAATGGCGCGGCCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGCT
TCAAGCAGTAGACAAGCAAAAGCCAACCTTAGTTCATGCGGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTAG
TGGCTAAAGTGATCAATGCGGGTGGTGCAGTGTGTTTGGCTAGTCCTCGCATAGATGTTTGTTTGGAGCTGTACAAGCGC
CTGCAACAGGATTTTTCTTGCGGGATAGCTTTGCTACATGGAGAATCGGAACCTTATTTTCGAACACCACTAGTTGTTGC
AACAACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCTTTTCCTTATGTTG
ATAATCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGGAGAATGGATTGAGAATCTTTTTAACAGCGACTTCGACC
AATGAGTTAGATAAAAAGGTCCGTTTAGGAGAACTAAAAAGACTGAATTTACCGAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAACCAATTTGGTTATCGGATTTTAATCGCTACTTAGACAAGAATCGTTTGTCACCAAAGTTAAAGTCCTATA
TTGAGAAGCAGAGAAAGACAGCTTATCCGTTACTCATTTTTGCTTCAGAAATTAAGAAAGGGGAGCAGTTAGAAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAGCAAGTACAAGCTTT
TCGAGATGGAGAACTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAATAGAGGCCAATCATCGTTTGTTTACCAAGTCTAGTTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGATGGGTTAAATGCTTCAATCAAGAAGGCGATTAAGGAAATTCAGATGATGAA
TAAGGAGGCTGGTCTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(293-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae D39

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae R6

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae TIGR4

98.843

100

0.988
  comFA/cflA Streptococcus mitis NCTC 12261

92.824

100

0.928
  comFA/cflA Streptococcus mitis SK321

91.667

100

0.917
  comFA Lactococcus lactis subsp. cremoris KW2

52.206

94.444

0.493
  comFA Latilactobacillus sakei subsp. sakei 23K

39.609

94.676

0.375