Detailed information NTG0896077

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: LLNCDO184_RS03620
• Genome accession: NZ_CP155124
• Coordinates: 648780..650663 (+)
• Length: 627 a.a.
• NCBI ID: WP_063283696.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain NCDO184
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 643780..655663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLNCDO184_RS03590 (LLNCDO184_03580)	-	644894..645136 (+)	243	WP_003131476.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
LLNCDO184_RS03595 (LLNCDO184_03585)	amaP	645164..645724 (+)	561	WP_010906186.1	alkaline shock response membrane anchor protein AmaP	-
LLNCDO184_RS03600 (LLNCDO184_03590)	-	645735..645923 (+)	189	WP_012898445.1	DUF2273 domain-containing protein	-
LLNCDO184_RS03605 (LLNCDO184_03595)	-	645944..646450 (+)	507	WP_003131479.1	Asp23/Gls24 family envelope stress response protein	-
LLNCDO184_RS03610 (LLNCDO184_03600)	rsmB	646649..647923 (+)	1275	WP_014570715.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LLNCDO184_RS03615 (LLNCDO184_03605)	-	648004..648780 (+)	777	WP_003130802.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
LLNCDO184_RS03620 (LLNCDO184_03610)	pknB	648780..650663 (+)	1884	WP_063283696.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
LLNCDO184_RS03625 (LLNCDO184_03615)	rpsO	650845..651114 (+)	270	WP_010906184.1	30S ribosomal protein S15	-
LLNCDO184_RS03630 (LLNCDO184_03620)	proC	651193..651981 (-)	789	WP_063283697.1	pyrroline-5-carboxylate reductase	-
LLNCDO184_RS03635 (LLNCDO184_03625)	glmU	652209..653585 (+)	1377	WP_003130798.1	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	-
LLNCDO184_RS03640 (LLNCDO184_03630)	-	653690..654274 (+)	585	WP_012898439.1	NUDIX hydrolase	-
LLNCDO184_RS03645 (LLNCDO184_03635)	macP	654267..654545 (+)	279	WP_003130796.1	cell wall synthase accessory phosphoprotein MacP	-
LLNCDO184_RS03650 (LLNCDO184_03640)	-	654578..655258 (+)	681	WP_003130794.1	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	-

Sequence

Protein

• Length: 627 a.a.
• Molecular weight: 67947.03 Da
• Isoelectric Point: 4.8251

>NTDB_id=896077 LLNCDO184_RS03620 WP_063283696.1 648780..650663(+) (pknB) [Lactococcus lactis subsp. lactis strain NCDO184]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSRSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVGNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKIPNVTNSTLSQAKSKIKDAKLKVGTVHKQQSSTI
AEGKVIKTDPTSGTTVRSNSSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPNVGT
SVDPTQEIVVTYSVYTAPSSSSTTSESTTTSETSSSTTSSTSSSTTSQPSTDNNNSSKESSTTSSSS

Nucleotide

• Length: 1884 bp

>NTDB_id=896077 LLNCDO184_RS03620 WP_063283696.1 648780..650663(+) (pknB) [Lactococcus lactis subsp. lactis strain NCDO184]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGTGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGGAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAGCTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATTAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGGAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CACTTAGCCAAGCAAAAAGCAAAATTAAAGATGCAAAACTTAAAGTGGGAACAGTTCATAAACAACAAAGTTCAACGATT
GCTGAAGGAAAAGTTATCAAGACTGATCCAACTAGTGGAACAACCGTGAGATCTAATAGCTCCGTTGATATCTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAATCAACAAGCTGATGGTTATGTTTACTCAGTCTATCCAAATGTAGGGACA
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGCGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACTACGACGTCTGAAACTTCATCAAGTACAACTTCAAGTACTTCAAGCTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAGCAAAGAATCTTCAACAACGTCATCAAGTAGTTGA

Domains

Predicted by InterProScan.

• PASTA domain (PASTA) (365-428)

• PASTA domain (PASTA) (506-573)

• PASTA domain (PASTA) (434-501)

• Protein kinase domain (Pkinase) (12-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	49.265	86.762	0.427
stkP/pknB	Streptococcus salivarius strain HSISS4	51.445	82.775	0.426
stkP	Streptococcus pneumoniae TIGR4	48.024	80.702	0.388
stkP	Streptococcus pneumoniae D39	47.826	80.702	0.386
stkP	Streptococcus pneumoniae R6	47.826	80.702	0.386
stkP	Streptococcus pneumoniae Rx1	47.628	80.702	0.384