Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4700_RS05390 Genome accession   NZ_CP137112
Coordinates   1045882..1046544 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 02H2025     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1040882..1051544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4700_RS05365 - 1041032..1041298 (-) 267 WP_001278167.1 Veg family protein -
  R4700_RS05370 dnaB 1041300..1042652 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R4700_RS05375 rplI 1042696..1043148 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4700_RS05380 - 1043145..1045118 (-) 1974 WP_044790958.1 DHH family phosphoesterase -
  R4700_RS05385 hpf 1045254..1045802 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4700_RS05390 comFC/cflB 1045882..1046544 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  R4700_RS05395 comFA/cflA 1046541..1047839 (-) 1299 WP_050095242.1 DEAD/DEAH box helicase Machinery gene
  R4700_RS05400 - 1047895..1048530 (+) 636 WP_000395729.1 YigZ family protein -
  R4700_RS05405 cysK 1048814..1049734 (+) 921 WP_000029866.1 cysteine synthase A -
  R4700_RS05410 - 1049973..1050323 (-) 351 Protein_1027 IS66 family transposase -
  R4700_RS05415 - 1050323..1050615 (+) 293 Protein_1028 transposase -
  R4700_RS05420 tnpB 1050756..1051079 (-) 324 WP_000973416.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=896037 R4700_RS05390 WP_000649971.1 1045882..1046544(-) (comFC/cflB) [Streptococcus pneumoniae strain 02H2025]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=896037 R4700_RS05390 WP_000649971.1 1045882..1046544(-) (comFC/cflB) [Streptococcus pneumoniae strain 02H2025]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914