Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   R4706_RS08130 Genome accession   NZ_CP137111
Coordinates   1585400..1587379 (+) Length   659 a.a.
NCBI ID   WP_044727877.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 17023     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1580400..1592379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS08115 fmt 1582407..1583342 (+) 936 WP_044727878.1 methionyl-tRNA formyltransferase -
  R4706_RS08120 rsmB 1583335..1584648 (+) 1314 WP_044727880.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  R4706_RS08125 - 1584663..1585403 (+) 741 WP_000406247.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  R4706_RS08130 stkP 1585400..1587379 (+) 1980 WP_044727877.1 serine/threonine-protein kinase StkP Regulator
  R4706_RS08135 - 1587494..1588252 (+) 759 WP_000392880.1 threonine/serine exporter ThrE family protein -
  R4706_RS08140 - 1588254..1588703 (+) 450 WP_000176924.1 threonine/serine exporter family protein -
  R4706_RS08145 - 1588765..1589389 (+) 625 Protein_1560 transposase -
  R4706_RS08150 - 1589457..1589705 (+) 249 WP_317815457.1 hypothetical protein -
  R4706_RS08155 - 1589836..1591008 (+) 1173 WP_000151960.1 hydroxymethylglutaryl-CoA synthase -
  R4706_RS08160 - 1591008..1592282 (+) 1275 WP_044727726.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 72373.92 Da        Isoelectric Point: 9.0945

>NTDB_id=895979 R4706_RS08130 WP_044727877.1 1585400..1587379(+) (stkP) [Streptococcus pneumoniae strain 17023]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQTVTEETYQPQAPKKHRFKMRYLILLANLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=895979 R4706_RS08130 WP_044727877.1 1585400..1587379(+) (stkP) [Streptococcus pneumoniae strain 17023]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCAGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACCAGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGCTCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGACTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAACCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATCTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCTTCTGATGTTATCGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAGAGTGAGGCTGGAACGGTC
CTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGTAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTC
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(513-577)

PASTA domain (PASTA)

(582-651)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

99.545

100

0.995
  stkP Streptococcus pneumoniae D39

99.393

100

0.994
  stkP Streptococcus pneumoniae R6

99.393

100

0.994
  stkP Streptococcus pneumoniae Rx1

99.241

100

0.992
  pknB Streptococcus mutans UA159

52.65

88.771

0.467
  stkP/pknB Streptococcus salivarius strain HSISS4

51.807

88.164

0.457