Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   R4706_RS05080 Genome accession   NZ_CP137111
Coordinates   1015123..1016472 (-) Length   449 a.a.
NCBI ID   WP_000801618.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 17023     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1010123..1021472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS05065 - 1010319..1014044 (-) 3726 WP_000361167.1 phosphoribosylformylglycinamidine synthase -
  R4706_RS05070 - 1014101..1014244 (-) 144 WP_078133500.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  R4706_RS05075 purC 1014246..1014953 (-) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  R4706_RS05080 comB 1015123..1016472 (-) 1350 WP_000801618.1 competence pheromone export protein ComB Regulator
  R4706_RS05085 comA 1016485..1018638 (-) 2154 WP_000668291.1 peptide cleavage/export ABC transporter ComA Regulator
  R4706_RS05090 - 1019225..1019350 (-) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  R4706_RS05095 blpU 1019353..1019583 (-) 231 WP_001093068.1 bacteriocin-like peptide BlpU -
  R4706_RS05100 - 1019786..1020085 (-) 300 Protein_1014 transposase family protein -
  R4706_RS05105 - 1020122..1020355 (-) 234 WP_000136447.1 acyl carrier protein -
  R4706_RS05110 plsX 1020361..1021353 (-) 993 WP_000717458.1 phosphate acyltransferase PlsX -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49615.49 Da        Isoelectric Point: 5.3895

>NTDB_id=895935 R4706_RS05080 WP_000801618.1 1015123..1016472(-) (comB) [Streptococcus pneumoniae strain 17023]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=895935 R4706_RS05080 WP_000801618.1 1015123..1016472(-) (comB) [Streptococcus pneumoniae strain 17023]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCAACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

99.109

100

0.991
  comB Streptococcus pneumoniae Rx1

98.886

100

0.989
  comB Streptococcus pneumoniae D39

98.886

100

0.989
  comB Streptococcus pneumoniae R6

98.886

100

0.989
  comB Streptococcus mitis SK321

95.1

100

0.951
  comB Streptococcus mitis NCTC 12261

94.655

100

0.947
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555