Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R4699_RS06855 Genome accession   NZ_CP137105
Coordinates   1359675..1360262 (+) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain 16H2092     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1354675..1365262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS06820 rimP 1355201..1355680 (-) 480 WP_001808916.1 ribosome maturation factor RimP -
  R4699_RS06825 trmB 1355806..1356441 (-) 636 WP_001266078.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  R4699_RS06830 ccrZ 1356438..1357232 (-) 795 WP_000363002.1 cell cycle regulator CcrZ -
  R4699_RS06835 - 1357394..1358005 (-) 612 WP_000394028.1 CPBP family intramembrane glutamic endopeptidase -
  R4699_RS06840 blpZ 1358156..1358389 (-) 234 WP_000276498.1 immunity protein BlpZ -
  R4699_RS06845 - 1358431..1359120 (-) 690 WP_000760515.1 CPBP family intramembrane glutamic endopeptidase -
  R4699_RS06850 - 1359152..1359385 (-) 234 WP_001093273.1 hypothetical protein -
  R4699_RS06855 comA/nlmT 1359675..1360262 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R4699_RS06860 - 1360189..1361832 (+) 1644 Protein_1341 peptide cleavage/export ABC transporter -
  R4699_RS06865 - 1361843..1363204 (+) 1362 WP_050104729.1 bacteriocin secretion accessory protein -
  R4699_RS06870 blpC 1363261..1363416 (+) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  R4699_RS06875 - 1363459..1364799 (-) 1341 WP_050104728.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=895487 R4699_RS06855 WP_000205166.1 1359675..1360262(+) (comA/nlmT) [Streptococcus pneumoniae strain 16H2092]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=895487 R4699_RS06855 WP_000205166.1 1359675..1360262(+) (comA/nlmT) [Streptococcus pneumoniae strain 16H2092]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497