Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4713_RS05380 Genome accession   NZ_CP137103
Coordinates   1022171..1022833 (-) Length   220 a.a.
NCBI ID   WP_000649968.1    Uniprot ID   A0A098Z9B1
Organism   Streptococcus pneumoniae strain 21334     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1017171..1027833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4713_RS05355 - 1017321..1017587 (-) 267 WP_001278167.1 Veg family protein -
  R4713_RS05360 dnaB 1017589..1018941 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R4713_RS05365 rplI 1018985..1019437 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4713_RS05370 - 1019434..1021407 (-) 1974 WP_000715111.1 DHH family phosphoesterase -
  R4713_RS05375 hpf 1021543..1022091 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4713_RS05380 comFC/cflB 1022171..1022833 (-) 663 WP_000649968.1 ComF family protein Machinery gene
  R4713_RS05385 comFA/cflA 1022830..1024128 (-) 1299 WP_000867608.1 DEAD/DEAH box helicase Machinery gene
  R4713_RS05390 - 1024184..1024819 (+) 636 WP_000395746.1 YigZ family protein -
  R4713_RS05395 cysK 1025104..1026024 (+) 921 WP_000029860.1 cysteine synthase A -
  R4713_RS05400 - 1026099..1026637 (-) 539 Protein_1020 transposase -
  R4713_RS05405 - 1026610..1026918 (+) 309 Protein_1021 transposase -
  R4713_RS05410 tnpB 1027059..1027382 (-) 324 WP_000973416.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25203.05 Da        Isoelectric Point: 7.7116

>NTDB_id=895348 R4713_RS05380 WP_000649968.1 1022171..1022833(-) (comFC/cflB) [Streptococcus pneumoniae strain 21334]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=895348 R4713_RS05380 WP_000649968.1 1022171..1022833(-) (comFC/cflB) [Streptococcus pneumoniae strain 21334]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z9B1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae TIGR4

99.091

100

0.991
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914
  comFC/cflB Streptococcus mitis NCTC 12261

90.909

100

0.909