Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   R4709_RS02745 Genome accession   NZ_CP137102
Coordinates   544960..545697 (-) Length   245 a.a.
NCBI ID   WP_001219137.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H3071-2     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 539960..550697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4709_RS02720 blpA 540336..541604 (+) 1269 Protein_541 peptide cleavage/export ABC transporter BlpA -
  R4709_RS02725 comA/nlmT 541814..541978 (+) 165 WP_306420852.1 hypothetical protein Regulator
  R4709_RS02730 - 541989..543350 (+) 1362 WP_050233594.1 bacteriocin secretion accessory protein -
  R4709_RS02735 blpC 543407..543562 (+) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  R4709_RS02740 - 543606..544946 (-) 1341 WP_001099893.1 sensor histidine kinase -
  R4709_RS02745 comE/blpR 544960..545697 (-) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  R4709_RS02750 - 545702..546040 (-) 339 WP_317803430.1 LytTR family DNA-binding domain-containing protein -
  R4709_RS02755 - 546317..546646 (+) 330 WP_000132572.1 hypothetical protein -
  R4709_RS02760 - 546814..547863 (-) 1050 WP_000653751.1 ABC transporter permease -
  R4709_RS02765 pptA 547860..548591 (-) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  R4709_RS02770 - 548659..549069 (+) 411 WP_001278304.1 HIT family protein -
  R4709_RS02775 - 549079..549366 (+) 288 WP_000777753.1 hypothetical protein -
  R4709_RS02780 - 549528..549722 (+) 195 WP_001808905.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28768.92 Da        Isoelectric Point: 6.2366

>NTDB_id=895234 R4709_RS02745 WP_001219137.1 544960..545697(-) (comE/blpR) [Streptococcus pneumoniae strain 16H3071-2]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=895234 R4709_RS02745 WP_001219137.1 544960..545697(-) (comE/blpR) [Streptococcus pneumoniae strain 16H3071-2]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCTGAGTTCTTTTGAAGTTTTTGGTAAGCCAGATCAATTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38