Detailed information NTG0895200

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: R4710_RS06190
• Genome accession: NZ_CP137101
• Coordinates: 1156824..1158173 (+)
• Length: 449 a.a.
• NCBI ID: WP_000801615.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P2012-2
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1151824..1163173

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4710_RS06170	-	1152731..1153213 (+)	483	WP_001232094.1	stage II sporulation protein M	-
R4710_RS06175	-	1153210..1153806 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
R4710_RS06180	-	1153787..1154278 (+)	492	WP_000671990.1	hypothetical protein	-
R4710_RS06185	comA	1154658..1156811 (+)	2154	WP_000668290.1	peptide cleavage/export ABC transporter ComA	Regulator
R4710_RS06190	comB	1156824..1158173 (+)	1350	WP_000801615.1	competence pheromone export protein ComB	Regulator
R4710_RS06195	purC	1158343..1159050 (+)	708	WP_001861988.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
R4710_RS06200	-	1159107..1162832 (+)	3726	WP_050245344.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49597.45 Da
• Isoelectric Point: 5.3895

>NTDB_id=895200 R4710_RS06190 WP_000801615.1 1156824..1158173(+) (comB) [Streptococcus pneumoniae strain 16P2012-2]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=895200 R4710_RS06190 WP_000801615.1 1156824..1158173(+) (comB) [Streptococcus pneumoniae strain 16P2012-2]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTACTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae Rx1	99.555	100	0.996
comB	Streptococcus pneumoniae D39	99.555	100	0.996
comB	Streptococcus pneumoniae R6	99.555	100	0.996
comB	Streptococcus pneumoniae TIGR4	99.332	100	0.993
comB	Streptococcus mitis SK321	94.878	100	0.949
comB	Streptococcus mitis NCTC 12261	94.432	100	0.944
comB	Streptococcus gordonii str. Challis substr. CH1	55.556	100	0.557