Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4703_RS04565 Genome accession   NZ_CP137100
Coordinates   835365..835667 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LYP     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 830365..840667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4703_RS04530 rnpA 831044..831415 (-) 372 WP_000739244.1 ribonuclease P protein component -
  R4703_RS04535 - 831432..831563 (-) 132 WP_000768904.1 hypothetical protein -
  R4703_RS04540 - 831564..832754 (-) 1191 WP_000167770.1 acetate kinase -
  R4703_RS04545 comYH 832805..833758 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  R4703_RS04550 - 833819..834413 (-) 595 Protein_870 class I SAM-dependent methyltransferase -
  R4703_RS04555 comGG/cglG 834550..834963 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4703_RS04560 comGF/cglF 834941..835402 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4703_RS04565 comGE/cglE 835365..835667 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4703_RS04570 comGD/cglD 835630..836034 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4703_RS04575 comGC/cglC 836027..836293 (-) 267 WP_050129046.1 competence type IV pilus major pilin ComGC Machinery gene
  R4703_RS04580 - 836295..836552 (-) 258 WP_000698513.1 hypothetical protein -
  R4703_RS04585 - 836784..837740 (-) 957 WP_219576515.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R4703_RS04590 - 837743..838078 (-) 336 WP_050200954.1 phage holin -
  R4703_RS04595 - 838082..838381 (-) 300 WP_001811580.1 hypothetical protein -
  R4703_RS04600 - 838390..838740 (-) 351 WP_000852245.1 hypothetical protein -
  R4703_RS04605 - 838743..838946 (-) 204 WP_001091112.1 hypothetical protein -
  R4703_RS04610 - 838927..839044 (-) 118 Protein_882 dihydrodipicolinate reductase -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=895099 R4703_RS04565 WP_000413382.1 835365..835667(-) (comGE/cglE) [Streptococcus pneumoniae strain LYP]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=895099 R4703_RS04565 WP_000413382.1 835365..835667(-) (comGE/cglE) [Streptococcus pneumoniae strain LYP]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4