Detailed information NTG0895098

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R4703_RS04560
• Genome accession: NZ_CP137100
• Coordinates: 834941..835402 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain LYP
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 829941..840402

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4703_RS04525	-	830245..831069 (-)	825	WP_001832473.1	membrane protein insertase YidC	-
R4703_RS04530	rnpA	831044..831415 (-)	372	WP_000739244.1	ribonuclease P protein component	-
R4703_RS04535	-	831432..831563 (-)	132	WP_000768904.1	hypothetical protein	-
R4703_RS04540	-	831564..832754 (-)	1191	WP_000167770.1	acetate kinase	-
R4703_RS04545	comYH	832805..833758 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
R4703_RS04550	-	833819..834413 (-)	595	Protein_870	class I SAM-dependent methyltransferase	-
R4703_RS04555	comGG/cglG	834550..834963 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4703_RS04560	comGF/cglF	834941..835402 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4703_RS04565	comGE/cglE	835365..835667 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4703_RS04570	comGD/cglD	835630..836034 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4703_RS04575	comGC/cglC	836027..836293 (-)	267	WP_050129046.1	competence type IV pilus major pilin ComGC	Machinery gene
R4703_RS04580	-	836295..836552 (-)	258	WP_000698513.1	hypothetical protein	-
R4703_RS04585	-	836784..837740 (-)	957	WP_219576515.1	N-acetylmuramoyl-L-alanine amidase family protein	-
R4703_RS04590	-	837743..838078 (-)	336	WP_050200954.1	phage holin	-
R4703_RS04595	-	838082..838381 (-)	300	WP_001811580.1	hypothetical protein	-
R4703_RS04600	-	838390..838740 (-)	351	WP_000852245.1	hypothetical protein	-
R4703_RS04605	-	838743..838946 (-)	204	WP_001091112.1	hypothetical protein	-
R4703_RS04610	-	838927..839044 (-)	118	Protein_882	dihydrodipicolinate reductase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=895098 R4703_RS04560 WP_000250540.1 834941..835402(-) (comGF/cglF) [Streptococcus pneumoniae strain LYP]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=895098 R4703_RS04560 WP_000250540.1 834941..835402(-) (comGF/cglF) [Streptococcus pneumoniae strain LYP]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922