Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   AAIS09_RS09350 Genome accession   NZ_CP154595
Coordinates   1833281..1833760 (-) Length   159 a.a.
NCBI ID   WP_000588864.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain serotype 4     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1828281..1838760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAIS09_RS09350 (AAIS09_09335) comX/comX2 1833281..1833760 (-) 480 WP_000588864.1 sigma-70 family RNA polymerase sigma factor Regulator
  AAIS09_RS09355 (AAIS09_09340) nusG 1833882..1834418 (-) 537 WP_000376736.1 transcription termination/antitermination protein NusG -
  AAIS09_RS09360 (AAIS09_09345) secE 1834473..1834649 (-) 177 WP_001210991.1 preprotein translocase subunit SecE -
  AAIS09_RS09365 (AAIS09_09350) rpmG 1834659..1834811 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  AAIS09_RS09370 (AAIS09_09355) pbp2a 1834864..1837059 (-) 2196 WP_061813629.1 penicillin-binding protein PBP2A -
  AAIS09_RS09375 (AAIS09_09360) - 1837146..1838021 (+) 876 WP_078152404.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19845.46 Da        Isoelectric Point: 7.3797

>NTDB_id=893510 AAIS09_RS09350 WP_000588864.1 1833281..1833760(-) (comX/comX2) [Streptococcus pneumoniae strain serotype 4]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=893510 AAIS09_RS09350 WP_000588864.1 1833281..1833760(-) (comX/comX2) [Streptococcus pneumoniae strain serotype 4]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGCAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/comX1 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

89.937

100

0.899
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

89.873

99.371

0.893
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus mutans UA159

46

94.34

0.434
  comX/sigX Streptococcus suis isolate S10

45.033

94.969

0.428
  comX/sigX Streptococcus suis D9

45.033

94.969

0.428
  comX/sigX Streptococcus suis P1/7

45.033

94.969

0.428
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377