Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   R1Y14_RS07955 Genome accession   NZ_CP136899
Coordinates   1548940..1549677 (-) Length   245 a.a.
NCBI ID   WP_000782689.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ST62     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1543940..1554677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y14_RS07935 (R1Y14_07935) msrB 1545354..1546292 (-) 939 WP_000818203.1 peptide-methionine (R)-S-oxide reductase MsrB -
  R1Y14_RS07940 (R1Y14_07940) - 1546359..1546556 (-) 198 WP_025169195.1 hypothetical protein -
  R1Y14_RS07945 (R1Y14_07945) thrB 1546632..1547501 (-) 870 WP_000692438.1 homoserine kinase -
  R1Y14_RS07950 (R1Y14_07950) - 1547503..1548789 (-) 1287 WP_000216382.1 homoserine dehydrogenase -
  R1Y14_RS07955 (R1Y14_07955) mecA 1548940..1549677 (-) 738 WP_000782689.1 adaptor protein MecA Regulator
  R1Y14_RS07960 (R1Y14_07960) - 1549877..1550911 (-) 1035 WP_000461498.1 hypothetical protein -
  R1Y14_RS07965 (R1Y14_07965) - 1550940..1552373 (-) 1434 WP_001813454.1 O-antigen polysaccharide polymerase Wzy family protein -
  R1Y14_RS07970 (R1Y14_07970) - 1552389..1553375 (-) 987 WP_000446977.1 glycosyltransferase family 2 protein -
  R1Y14_RS07975 (R1Y14_07975) - 1553377..1554480 (-) 1104 WP_000225903.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28380.20 Da        Isoelectric Point: 4.0385

>NTDB_id=893257 R1Y14_RS07955 WP_000782689.1 1548940..1549677(-) (mecA) [Streptococcus pneumoniae strain ST62]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFENLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=893257 R1Y14_RS07955 WP_000782689.1 1548940..1549677(-) (mecA) [Streptococcus pneumoniae strain ST62]
ATGAAAATGAAACAAATTAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGAATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGCTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTGACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAAACTTATCGGATTTGCCAGATATGGAAGAATTGGCTCAAATGTCTCCAGATGAATTTAT
CAAAACCCTGGAAAAAAGCATCGCAGACAAAACCAAGGATGATATCGAAGCCATTCAATCTCTTGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAAGAGCAGGCTGAACAAGAAGCTGAGAGTAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTAGCTTTTGCCAAGACAGTGACTTTTGAAATGGAAACTTCTGAACTCTACAAAATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGCCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGCTCAGTCTTACAAGAGTATGGTCAAGTCTTGATGAGTCACGATGCAGTGCTCAAT
CTGCAAAAAATCGGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

99.184

100

0.992
  mecA Streptococcus pneumoniae D39

99.184

100

0.992
  mecA Streptococcus pneumoniae R6

99.184

100

0.992
  mecA Streptococcus pneumoniae TIGR4

98.776

100

0.988
  mecA Streptococcus thermophilus LMD-9

47.39

100

0.482
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.478
  mecA Streptococcus mutans UA159

47.755

100

0.478