Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   R1Y14_RS01810 Genome accession   NZ_CP136899
Coordinates   331965..333290 (-) Length   441 a.a.
NCBI ID   WP_001860404.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ST62     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 326965..338290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y14_RS01785 (R1Y14_01785) - 328671..330303 (-) 1633 Protein_315 YhgE/Pip family protein -
  R1Y14_RS01790 (R1Y14_01790) - 330431..330973 (+) 543 WP_001158266.1 TetR/AcrR family transcriptional regulator -
  R1Y14_RS01805 (R1Y14_01805) comE 331216..331968 (-) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  R1Y14_RS01810 (R1Y14_01810) comD/comD1 331965..333290 (-) 1326 WP_001860404.1 competence system sensor histidine kinase ComD Regulator
  R1Y14_RS01815 (R1Y14_01815) comC/comC1 333311..333436 (-) 126 WP_000799689.1 competence-stimulating peptide ComC Regulator
  R1Y14_RS01825 (R1Y14_01825) rlmH 333719..334198 (-) 480 WP_000695929.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  R1Y14_RS01830 (R1Y14_01830) htrA 334381..335562 (+) 1182 WP_000681601.1 S1C family serine protease Regulator
  R1Y14_RS01835 (R1Y14_01835) spo0J 335620..336378 (+) 759 WP_000410378.1 ParB/RepB/Spo0J family partition protein Regulator
  R1Y14_RS01840 (R1Y14_01840) dnaA 336591..337952 (+) 1362 WP_000660615.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51210.76 Da        Isoelectric Point: 6.9339

>NTDB_id=893225 R1Y14_RS01810 WP_001860404.1 331965..333290(-) (comD/comD1) [Streptococcus pneumoniae strain ST62]
MDLFGFGTVIVHLLIISHNYHLICKGQINRKELFVFGAYTLLTEIVFDFPLYILYLDGLGIAIFLFPLGLYSYFRWMKQY
ERDRGLFLSLLLSLLYESTHNFLSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=893225 R1Y14_RS01810 WP_001860404.1 331965..333290(-) (comD/comD1) [Streptococcus pneumoniae strain ST62]
ATGGATTTATTTGGATTTGGGACAGTTATTGTTCATCTTTTAATTATTAGTCACAACTACCATTTAATTTGTAAAGGTCA
AATAAATAGAAAAGAATTATTCGTTTTTGGTGCTTATACATTACTAACAGAAATAGTATTTGATTTTCCCTTATATATTC
TATATTTAGATGGGTTAGGGATTGCAATATTTTTATTTCCTTTGGGATTATATTCCTATTTTCGATGGATGAAACAGTAT
GAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACTTT
CTCCTCTATAACAGGAGATAATTTTGTTTTACAATATCATTTCCCATTCTTTTTCGTTGTGACGGTGTTAACCTATTTTG
TTACATTAAAAATCATTTATTATTTCCATTTGGAACTAGCCTATTTTGACAAGGACTACCTTTATCCTTTCTTGAAAAAA
GTATTTTTTGCTTTACTATTGCTACATATTGTATCTTTCGTTTCAGATATGGTAAGTACGATTAAACATTTGAATAGTTT
TGGAAGTATTTTGTCATCTATTGTCTTTATCTCTCTCCTTTTGACCTTCTTTGCAATGAATTCTCATAAAGTTCAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTACACAGATGAAATTGTTGGTCTGTAT
AATGAAATCCGTGGTTTTCGACATGATTATGCTGGAATGCTTGTCAGCATGCAGATGGCAATTGACAGTGGTAATTTACA
GGAAATTGACAGAATTTACAATGAAGTTTTAGTCAAAGCAAATCATAAATTGCGTTCAGATAAGTACACTTACTTTGATT
TGAACAACATAGAAGACTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTTCCAATTGAACTATTGGATTTGGTTCGTATCATGAGCGTTTTATTGAA
TAATGCTGTCGAAGGATCGGCTGATAGCTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTTA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCCTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTCGGATTAAATAATGTGAAAGAACTACTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus pneumoniae Rx1

98.639

100

0.986
  comD/comD1 Streptococcus pneumoniae D39

98.639

100

0.986
  comD/comD1 Streptococcus pneumoniae R6

98.639

100

0.986
  comD/comD2 Streptococcus pneumoniae TIGR4

96.372

100

0.964
  comD Streptococcus mitis SK321

92.063

100

0.921
  comD Streptococcus mitis NCTC 12261

86.168

100

0.862
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.604

85.941

0.426
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.465

84.807

0.419