Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RYQ61_RS06035 Genome accession   NZ_CP136799
Coordinates   1158714..1159463 (+) Length   249 a.a.
NCBI ID   WP_048785021.1    Uniprot ID   -
Organism   Streptococcus intermedius strain XH2169     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1153714..1164463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RYQ61_RS06020 (RYQ61_06020) - 1154097..1155662 (-) 1566 WP_048785015.1 ABC transporter substrate-binding protein/permease -
  RYQ61_RS06025 (RYQ61_06025) - 1155789..1157678 (+) 1890 WP_117276643.1 DUF2207 domain-containing protein -
  RYQ61_RS06030 (RYQ61_06030) - 1157745..1158587 (+) 843 WP_048785019.1 undecaprenyl-diphosphate phosphatase -
  RYQ61_RS06035 (RYQ61_06035) mecA 1158714..1159463 (+) 750 WP_048785021.1 adaptor protein MecA Regulator
  RYQ61_RS06040 (RYQ61_06040) - 1159460..1160626 (+) 1167 WP_117276642.1 glycosyltransferase family 4 protein -
  RYQ61_RS06045 (RYQ61_06045) sufC 1160717..1161487 (+) 771 WP_003073743.1 Fe-S cluster assembly ATPase SufC -
  RYQ61_RS06050 (RYQ61_06050) sufD 1161527..1162789 (+) 1263 WP_117276641.1 Fe-S cluster assembly protein SufD -
  RYQ61_RS06055 (RYQ61_06055) - 1162806..1164038 (+) 1233 WP_117276640.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 28992.75 Da        Isoelectric Point: 4.1530

>NTDB_id=892727 RYQ61_RS06035 WP_048785021.1 1158714..1159463(+) (mecA) [Streptococcus intermedius strain XH2169]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDIEAVRSLETAEAENSRSTSDMEEQEEDNDELTQKYIYYI
LKFANLREVIVFAKTVDYTVNTSELYKMDSYYYLTILVDIEGHPKRYPAWLLASMREHAEDTAVTRAVLQEHGYLLLVND
AVSNLQKVK

Nucleotide


Download         Length: 750 bp        

>NTDB_id=892727 RYQ61_RS06035 WP_048785021.1 1158714..1159463(+) (mecA) [Streptococcus intermedius strain XH2169]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTCGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGTT
TTTTGGATAGCGGTATGCTCAGTTTTCGTGTAACCCCTAAACCAGACCGACTGGATGTTTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAATTTTGATGATTTAGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCAGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGCAAAGACGATATTGAAGCTGTTCGGTCTTTGGAAACGGCAGAAGCAG
AAAATAGTAGAAGCACTTCTGATATGGAAGAACAAGAGGAAGATAATGACGAGCTAACACAAAAATATATATATTACATT
TTGAAGTTTGCCAACCTAAGAGAAGTGATTGTTTTTGCTAAAACGGTAGATTATACCGTCAATACTTCAGAGTTATACAA
AATGGACAGTTACTATTATTTGACAATTTTGGTTGATATTGAAGGCCATCCTAAGCGATATCCGGCTTGGCTTCTTGCAT
CTATGCGTGAACATGCAGAAGATACAGCTGTGACAAGAGCTGTTTTGCAAGAGCATGGTTACTTATTGCTTGTCAACGAT
GCGGTTTCCAATCTTCAAAAGGTTAAATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.145

99.598

0.679
  mecA Streptococcus pneumoniae D39

68.145

99.598

0.679
  mecA Streptococcus pneumoniae R6

68.145

99.598

0.679
  mecA Streptococcus pneumoniae TIGR4

67.742

99.598

0.675
  mecA Streptococcus mutans UA159

51.613

99.598

0.514
  mecA Streptococcus thermophilus LMD-9

45.703

100

0.47
  mecA Streptococcus thermophilus LMG 18311

45.312

100

0.466