Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   RWA15_RS12720 Genome accession   NZ_CP136127
Coordinates   2753647..2755818 (+) Length   723 a.a.
NCBI ID   WP_087912941.1    Uniprot ID   A0AAN1F0R2
Organism   Lacticaseibacillus casei strain LMG 24102     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2748647..2760818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RWA15_RS12700 (RWA15_12700) - 2748993..2750780 (-) 1788 WP_087912938.1 L-fucose isomerase -
  RWA15_RS12705 (RWA15_12705) - 2751513..2751878 (+) 366 WP_087912939.1 bacteriocin immunity protein -
  RWA15_RS12710 (RWA15_12710) - 2752128..2752292 (+) 165 WP_151466791.1 bacteriocin class II family protein -
  RWA15_RS12715 (RWA15_12715) - 2752802..2753590 (+) 789 WP_191992412.1 CPBP family intramembrane glutamic endopeptidase -
  RWA15_RS12720 (RWA15_12720) comA 2753647..2755818 (+) 2172 WP_087912941.1 peptide cleavage/export ABC transporter Regulator
  RWA15_RS12725 (RWA15_12725) - 2755830..2757206 (+) 1377 WP_087912942.1 bacteriocin secretion accessory protein -
  RWA15_RS12730 (RWA15_12730) - 2757360..2757629 (+) 270 WP_087912943.1 helix-turn-helix domain-containing protein -
  RWA15_RS12735 (RWA15_12735) - 2757734..2758600 (-) 867 WP_087912944.1 helix-turn-helix domain-containing protein -
  RWA15_RS12740 (RWA15_12740) - 2758872..2759654 (+) 783 WP_087912945.1 hypothetical protein -
  RWA15_RS12745 (RWA15_12745) - 2759644..2760324 (+) 681 WP_087912946.1 hypothetical protein -

Sequence

Protein


Download         Length: 723 a.a.        Molecular weight: 80205.07 Da        Isoelectric Point: 7.3860

>NTDB_id=888730 RWA15_RS12720 WP_087912941.1 2753647..2755818(+) (comA) [Lacticaseibacillus casei strain LMG 24102]
MTFFANFKTYYTSQIDERDCGVAALNTVLKRHGSDFSLAHLRNLAKTDNSGTTALGIVKAAQDLGFETKAIRADMSLFDA
NDVPYPFIAHVIKNGKLLHYYVVFKATKTHLIIGDPDPSVKLIKMPKERFAKEWSGVAIFLAPTSAYTPQKDTKGSLFAF
VPLLVKQKRLISEVVLAAVLITIISIAGSYFFQAIIDTYLPNAMRDTLSIIASGLIIAYLFQAIFTYAQSFLMIVLGQRL
TIDVTLGYVRHLFELPMSFFATRRVGEITSRFSDASKIIDALGSTIMTMFLDIWIVIAVGIFLAIQNTTLFLVSLVALPI
YFAVVWSFKTPFNRLNQDAMESNAIVSSSIIESLNGIETIKAMTGETTSYGKVDHEFVDLLKKTFSYQKTDQLQQAIKLA
VKMILNIVILWIGALLVMQNQMTLGQLFTYNALLTYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEFAKSRPITQP
QALQGDLQFDHVNFTYGYGPNVLTDLSLTIPLHTKLTIVGMSGSGKTTLAKLLVGFFDVASDQGKVLINQHDLSEVNRTT
LRQFINYVPQDPFIFSGTILDNLTLGSRPNLTQAEIEQACAAAEIKTDIEKMPLGYTTELSESGAALSGGQKQRLAIARA
LLSPAQVFIFDESTSSLDTITERNIVDHLMQLTDKTIIFVAHRLAIAARTDNVVVLDHGKLVEQGNHQELLAKGGYYARL
VNE

Nucleotide


Download         Length: 2172 bp        

>NTDB_id=888730 RWA15_RS12720 WP_087912941.1 2753647..2755818(+) (comA) [Lacticaseibacillus casei strain LMG 24102]
TTGACTTTTTTCGCTAACTTCAAAACATACTACACAAGCCAGATTGATGAACGTGATTGTGGCGTTGCTGCCCTTAACAC
GGTTCTTAAACGTCATGGATCAGACTTTTCTCTTGCTCATCTACGTAATTTAGCCAAGACAGACAACTCCGGCACCACCG
CCTTAGGCATTGTCAAAGCTGCCCAAGATTTAGGCTTTGAAACCAAAGCCATTCGGGCCGATATGTCCCTATTTGATGCC
AATGATGTTCCTTATCCGTTTATTGCCCACGTTATTAAAAATGGCAAGCTGCTCCACTACTACGTCGTTTTTAAGGCCAC
CAAAACGCACCTCATCATTGGCGATCCTGATCCGTCGGTCAAGCTCATCAAGATGCCTAAGGAACGGTTTGCCAAGGAAT
GGTCGGGGGTCGCCATCTTTTTAGCGCCGACTTCCGCATATACGCCTCAAAAAGACACCAAAGGCAGCTTATTTGCGTTT
GTACCGCTGTTAGTCAAGCAAAAGCGGCTGATTAGCGAAGTTGTTTTGGCCGCGGTCCTCATTACCATTATTAGCATTGC
CGGTTCCTATTTCTTCCAAGCCATCATTGATACCTATTTGCCCAATGCGATGCGCGACACGCTCTCGATCATTGCCTCTG
GCCTGATCATCGCTTACCTGTTCCAAGCAATCTTCACGTACGCCCAATCCTTCCTCATGATTGTGTTAGGACAGCGCCTC
ACCATTGACGTCACGCTAGGCTATGTGCGGCATTTATTTGAACTGCCGATGTCTTTCTTTGCGACCCGCCGTGTCGGGGA
AATCACCTCTCGCTTTTCCGATGCCAGTAAGATCATCGACGCCCTAGGTAGTACGATCATGACGATGTTTTTGGATATTT
GGATTGTCATTGCCGTCGGCATCTTCTTGGCCATCCAAAATACCACGCTCTTTTTGGTTTCATTGGTGGCTTTGCCGATT
TATTTTGCGGTTGTTTGGTCGTTTAAGACTCCCTTTAACCGCTTGAACCAAGATGCCATGGAAAGCAATGCCATTGTCAG
CTCATCAATTATTGAAAGCCTCAATGGTATTGAAACCATTAAAGCCATGACCGGAGAAACCACCAGCTATGGCAAGGTTG
ACCATGAGTTTGTCGATTTGCTTAAGAAGACGTTCAGCTATCAAAAAACTGATCAACTGCAACAAGCGATCAAGCTAGCA
GTCAAAATGATTTTAAACATCGTCATTTTGTGGATTGGCGCTTTGCTGGTCATGCAAAACCAGATGACCTTAGGCCAACT
GTTCACCTACAATGCCTTATTGACCTACTTCACCAATCCATTGGAAAGCATTATCAACTTACAGCCCAAGCTTCAAATGG
CGCGGGTCGCCAATAATCGACTCAACGAGGTTTACCTGGTTGAGTCCGAGTTTGCTAAATCCCGTCCCATCACCCAACCA
CAAGCCCTGCAAGGTGATCTTCAGTTCGATCACGTCAACTTCACCTACGGCTATGGGCCCAACGTCCTGACGGATCTTTC
GCTCACCATTCCGTTGCACACCAAGCTGACCATTGTTGGCATGAGTGGCTCCGGTAAAACGACGCTGGCTAAGCTCCTAG
TGGGGTTCTTTGACGTCGCGTCTGATCAAGGTAAGGTGCTTATCAACCAACACGACCTCAGCGAAGTTAATCGCACGACT
CTGCGACAGTTCATCAACTATGTCCCCCAGGACCCCTTCATTTTCTCGGGCACCATTCTCGACAACTTGACGCTGGGCAG
CCGTCCCAATCTAACCCAAGCGGAGATTGAACAGGCTTGTGCGGCGGCCGAGATCAAAACCGACATTGAGAAAATGCCAC
TAGGCTATACGACTGAACTAAGCGAAAGTGGGGCCGCCTTATCCGGCGGTCAAAAACAACGCTTAGCAATCGCGAGGGCG
CTGTTATCACCGGCCCAGGTCTTTATCTTTGACGAATCAACCAGCAGCCTGGATACCATCACCGAGCGCAACATTGTCGA
TCACCTAATGCAATTAACCGATAAGACCATCATTTTCGTCGCCCATCGTTTAGCCATTGCGGCCCGCACCGACAATGTAG
TGGTCTTGGATCATGGCAAATTGGTGGAACAGGGAAACCACCAGGAATTGCTAGCCAAAGGCGGCTACTACGCCCGTCTC
GTCAATGAGTGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(174-441)

ABC transporter (ABC_tran)

(503-655)

Peptidase C39 family (Peptidase_C39)

(9-145)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

57.483

98.893

0.568
  comA Streptococcus mitis SK321

56.783

98.893

0.562
  comA Streptococcus pneumoniae Rx1

56.503

98.893

0.559
  comA Streptococcus pneumoniae D39

56.503

98.893

0.559
  comA Streptococcus pneumoniae R6

56.503

98.893

0.559
  comA Streptococcus pneumoniae TIGR4

56.503

98.893

0.559
  comA Streptococcus gordonii str. Challis substr. CH1

55.944

98.893

0.553
  comA/nlmT Streptococcus mutans UA159

55.148

98.064

0.541