Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   RWA19_RS11280 Genome accession   NZ_CP136113
Coordinates   2400414..2402606 (-) Length   730 a.a.
NCBI ID   WP_049171127.1    Uniprot ID   A0AAP8IXT2
Organism   Lacticaseibacillus rhamnosus strain LMG 23551     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2395414..2407606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RWA19_RS11260 (RWA19_11260) - 2395633..2396715 (+) 1083 WP_049171123.1 aldo/keto reductase -
  RWA19_RS11265 (RWA19_11265) - 2397016..2398371 (-) 1356 WP_316054096.1 threonine/serine exporter family protein -
  RWA19_RS11270 (RWA19_11270) - 2398551..2398961 (-) 411 WP_049171125.1 hypothetical protein -
  RWA19_RS11275 (RWA19_11275) - 2399022..2400401 (-) 1380 WP_047677460.1 bacteriocin secretion accessory protein -
  RWA19_RS11280 (RWA19_11280) comA 2400414..2402606 (-) 2193 WP_049171127.1 peptide cleavage/export ABC transporter Regulator
  RWA19_RS11285 (RWA19_11285) - 2402901..2403056 (-) 156 WP_168163043.1 bacteriocin-like peptide, LSEI_2386 family -
  RWA19_RS11290 (RWA19_11290) - 2403236..2404531 (+) 1296 WP_047678343.1 GHKL domain-containing protein -
  RWA19_RS11295 (RWA19_11295) - 2404536..2405324 (+) 789 WP_047678346.1 response regulator transcription factor -
  RWA19_RS11300 (RWA19_11300) - 2406060..2406245 (+) 186 WP_080751332.1 bacteriocin -
  RWA19_RS11305 (RWA19_11305) - 2406722..2406964 (-) 243 WP_141746984.1 hypothetical protein -

Sequence

Protein


Download         Length: 730 a.a.        Molecular weight: 81493.76 Da        Isoelectric Point: 7.2454

>NTDB_id=888476 RWA19_RS11280 WP_049171127.1 2400414..2402606(-) (comA) [Lacticaseibacillus rhamnosus strain LMG 23551]
MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSLAHLRELAKTNQDGTTALGIVRAAEALAFETKPVQA
DMQLFDLEDVPYPFIAHVLKRGELLHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKED
KGSLFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGLLVAYLLQAVLTYGQNFLM
AVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFADANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLV
SLIAVPCYLVIVFAFQRPFDRLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQL
QQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEFKE
QRHLTERHLIEGPLRVRNVSFKYGFGQDVLKNVNLEVPENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPV
KDINLTTLRQYIEYVPQDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRVLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGKIVEQGDHATLLAQ
DGYYARLVHE

Nucleotide


Download         Length: 2193 bp        

>NTDB_id=888476 RWA19_RS11280 WP_049171127.1 2400414..2402606(-) (comA) [Lacticaseibacillus rhamnosus strain LMG 23551]
ATGGTTAAATACACCCCAAAACTAGGCCAGATCACCTACTACAAACGTTTCTACACCGCACAAGTTGACGAGCGTGACTG
TGGTGTGGCTGCGTTAAACATGCTGCTTAAATACAATGGGTCGGACTATTCGTTAGCCCACTTGCGCGAGTTAGCGAAGA
CAAATCAGGATGGCACGACTGCTTTGGGAATCGTTCGGGCGGCTGAAGCACTAGCGTTTGAGACGAAACCGGTGCAGGCG
GATATGCAGTTGTTTGATCTTGAGGATGTACCTTATCCGTTTATTGCCCATGTGCTGAAGCGCGGTGAATTGCTTCATTA
TTATGTTGTTTTTAAGGCAACGCGCACGAGTATTCTGATTGGCGATCCTGACCCGTCAGTGCGCATGACCTGGCTTTCGC
GAGAGGTGTTTGAAAAAGAATGGTCGGGTGTGGCCATCTTTATTGCACCGGCGCCGCAGTATCAGCCGCGTAAGGAGGAC
AAAGGCAGTTTGTTTGCGTTTGTACCCATGCTGGCTAAGCAAAAAGGTATTATCGCGAACATTATTCTGGCCGCGGTATT
GATTACGGTCATTAGTATCGTCGGGTCGTATTTTTTGCAGTCTATTATTGATACGTATATACCGAATGCCATGCGGACGA
CGATGGGGATGATTGCTAGTGGCCTTTTGGTGGCTTACTTGCTGCAAGCTGTGTTGACTTATGGCCAGAATTTTTTGATG
GCGGTGTTGGGGCAGCGGCTTGCGATTGATGTCATTTTAGGGTATGTGCGCCACTTATATGAATTGCCGATGTCGTTTTT
TTCAACTCGGCGGACCGGAGAGATTGTGTCGCGGTTTGCGGATGCGAATAAAATTATTGATGCGCTGGCCAATACGATTA
TGACGTTATTTTTGGATGTCTGGATTGTCCTAATATTAGGCATTGTTCTAGGGATCCAAAATGGGACTTTGTTTTTAGTG
TCATTGATTGCCGTGCCGTGTTACTTGGTGATTGTTTTTGCATTTCAGCGGCCGTTTGATCGGTTGAATCAAGAGACGAT
GGAAAGCAACGCAATCTTGAGTTCATCGATTATTGAAGATTTGAATGGCATTGAAACCATCAAGTCCTTGACCGGCGAAC
GAGTTAGCTATGAACGGGTTGATCGGGAATTTCTAACCTATTTGAAGAAGTCGTTTAGTTACACCAAGGCAGATCAGTTA
CAGCAAGCGATTAAAGGTCTGTTGAAGCTGGCGTTGAACGTTGTGGTGTTGTGGATTGGGGCAAGTTTGGTGATTGCGAA
TCGGATGAGTTTGGGGCAGATGCTGACCTTTAATGCACTGCTGTCATACTTTACGAATCCACTTGAAAGCATCATCAACC
TGCAGCCAAAGTTACAAATGGCGCGGGTTGCTAACAATCGTTTGAATGAGGTTTATCTGGTCGAATCGGAATTCAAAGAA
CAGCGGCACTTGACGGAGCGGCATTTAATCGAAGGCCCGTTACGCGTTCGGAATGTCTCGTTTAAATATGGTTTTGGCCA
AGATGTGTTGAAAAACGTCAACCTTGAAGTGCCGGAAAATGCTAAATATACCATTGTCGGCATGAGCGGTTCTGGTAAGT
CGACATTAGCAAAATTATTAGTTGGCTTTTACCCGGTTGATGCCGATAAAGGAACCATCACGTTTAATGGCATTCCGGTC
AAAGACATTAACCTGACAACATTACGGCAATATATTGAATATGTACCTCAGGATCCGTTTATTTTTTCGGGCACGGTGTT
GGAGAATTTGACGTTAGGTAGCCGTTCGGATGTTTCGGAACAAGACTTGACGCAGGCGTGTTTGGCTGCGGAAATTGCCG
CAGACATCGCAAACTTACCGCAGCAGTGGCAGACCAAACTGTCAGAAAGCGGCAGCATTTTATCAGGCGGTCAGAAGCAG
CGGCTGGCGATTGCACGGGCCTTGTTGTCACCGGCAAAAGTACTGATTTTTGACGAATCGACCAGCAGTCTGGATACCAT
TACAGAGCGAAAAATTGTCGATCGCGTGCTGGCAATGACGGATCGGACCATTATTTTTGTTGCCCATCGCTTAACCATTG
CGGCTAAAACCGAACAAATTGTGGTGATGGATCATGGCAAAATTGTGGAACAAGGTGACCATGCAACGTTGTTAGCCCAA
GACGGTTATTACGCGCGCTTGGTTCATGAGTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(510-662)

Peptidase C39 family (Peptidase_C39)

(18-152)

ABC transporter transmembrane region (ABC_membrane)

(180-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae D39

58.182

97.945

0.57
  comA Streptococcus pneumoniae R6

58.182

97.945

0.57
  comA Streptococcus pneumoniae Rx1

58.182

97.945

0.57
  comA Streptococcus pneumoniae TIGR4

57.762

97.945

0.566
  comA Streptococcus mitis NCTC 12261

57.762

97.945

0.566
  comA Streptococcus mitis SK321

57.622

97.945

0.564
  comA Streptococcus gordonii str. Challis substr. CH1

56.467

98.493

0.556
  comA/nlmT Streptococcus mutans UA159

53.686

98.493

0.529