Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   RRU92_RS10130 Genome accession   NZ_CP135436
Coordinates   2128379..2130262 (-) Length   627 a.a.
NCBI ID   WP_315639772.1    Uniprot ID   A0AA96MPS1
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2123379..2135262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS10105 (RRU92_10105) - 2124031..2124171 (-) 141 WP_315639764.1 hypothetical protein -
  RRU92_RS10110 (RRU92_10110) - 2124458..2125732 (-) 1275 WP_315639767.1 hydroxymethylglutaryl-CoA reductase, degradative -
  RRU92_RS10115 (RRU92_10115) - 2125732..2126904 (-) 1173 WP_315639769.1 hydroxymethylglutaryl-CoA synthase -
  RRU92_RS10120 (RRU92_10120) - 2127081..2127530 (-) 450 WP_049503410.1 threonine/serine exporter family protein -
  RRU92_RS10125 (RRU92_10125) - 2127532..2128290 (-) 759 WP_075230622.1 threonine/serine exporter family protein -
  RRU92_RS10130 (RRU92_10130) stkP 2128379..2130262 (-) 1884 WP_315639772.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RRU92_RS10135 (RRU92_10135) - 2130259..2130999 (-) 741 WP_315639774.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RRU92_RS10140 (RRU92_10140) rsmB 2131015..2132328 (-) 1314 WP_315639776.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  RRU92_RS10145 (RRU92_10145) fmt 2132321..2133256 (-) 936 WP_315639778.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68497.06 Da        Isoelectric Point: 9.1468

>NTDB_id=886567 RRU92_RS10130 WP_315639772.1 2128379..2130262(-) (stkP) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTKGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVSEMYVDLSSSLSYNRRNEAKRVFDDATKADTKTLPKVSQTTLTSIPKVQPQTESHQAT
KASPEVSAKKSVEKPVKKRRFKARYLVLLASFVLVAASLVWILSRTPATVEIPKVAGQTVAEAKETLKKANFEIGEEKTE
ASDTVEEGRVIRTDPDAGSARKEGSKVNLIISSGKQSFKIGNYIGRKSTDVIAELKGKKVPENLIKIEEEESSESEPGVV
LKQSLVEGTTYDLTKATSIVLTVAKKVTTVTMPSYIGSSLEFTKNNLIQIVGVKEANIEVVEVSTAPEGTAEGTVVDQSP
KLGEKVDLSTTRIKISIYKPKTPPSSSSVPSSSQRNSNRADNTVPSQSPSTPSSSTPTHVDEHNTDN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=886567 RRU92_RS10130 WP_315639772.1 2128379..2130262(-) (stkP) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGATCCAGATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAACAAATTGGCCGTGGAGGTATGGCGGATGTCTA
CCTGGCCAAGGATTTGATTTTAGACGGGGAAGAGGTAGCTGTAAAGGTCCTAAGGACTAACTACCAGACTGACCCGATTG
CTGTTGCTCGTTTTCAGCGTGAAGCGCGTGCAATGGCTGACTTAGATCATCCCCATATCGTTCGGATAACGGATATCGGC
GAAGAGGACGGTCAACAGTACCTGGCTATGGAATATGTAGCCGGTCTTGATCTCAAGCGCTATATCAAAGAACACTATCC
CCTCTCAAATGAAGAAGCTGTCCGTATTATGGGTCAGATTCTCTTAGCGATGCGCTTAGCGCACACTAAAGGTATTGTCC
ATCGTGACTTAAAACCTCAAAACATTCTTTTAACTCCGGATGGGACGGCCAAGGTAACTGACTTTGGGATTGCCGTAGCC
TTTGCAGAGACCAGTCTGACTCAGACCAACTCTATGCTGGGCTCTGTCCACTACTTGTCACCTGAGCAGGCTCGTGGCTC
TAAGGCAACTGTCCAGAGTGACATCTATGCCATGGGGATTATCTTCTATGAGATGTTGACAGGGCATATCCCTTATGATG
GCGATAGTGCAGTAACCATTGCCCTCCAGCATTTTCAAAAACCGCTGCCATCGGTCATCGCTGAAAATCCATCTGTCCCC
CAAGCCTTAGAAAATGTGGTTATCAAGGCAACTGCTAAAAAGCTTACGGATCGATACAAGTCGGTTTCAGAGATGTATGT
TGATTTATCTAGCAGTCTATCTTATAACCGCAGAAATGAAGCCAAACGTGTTTTTGATGATGCTACTAAGGCAGACACAA
AGACATTGCCAAAAGTTTCTCAGACAACCTTGACCTCTATTCCTAAGGTTCAACCACAGACAGAAAGCCATCAGGCAACT
AAAGCTAGCCCAGAAGTAAGTGCTAAAAAATCTGTGGAAAAACCAGTGAAAAAACGTCGTTTTAAAGCACGTTATCTAGT
TCTACTAGCAAGTTTCGTACTGGTTGCCGCTTCTCTGGTGTGGATTTTATCCAGAACACCAGCTACTGTTGAGATTCCAA
AAGTTGCAGGTCAAACTGTTGCTGAAGCTAAGGAAACCCTGAAAAAAGCGAATTTTGAGATTGGCGAGGAGAAGACCGAA
GCGAGTGATACCGTAGAAGAAGGTCGGGTTATCCGAACAGATCCAGATGCTGGCTCAGCTCGCAAAGAAGGGTCTAAAGT
TAATCTAATCATATCTTCAGGTAAACAATCATTTAAGATTGGAAACTATATTGGACGCAAATCTACTGATGTTATTGCAG
AATTGAAAGGGAAAAAAGTTCCTGAAAATCTGATTAAGATTGAAGAAGAAGAGTCCAGTGAATCAGAACCAGGTGTGGTT
TTAAAACAGAGCTTAGTAGAAGGTACGACTTATGATCTTACCAAGGCAACTTCTATCGTTTTGACTGTTGCTAAAAAGGT
GACAACCGTGACCATGCCAAGTTATATTGGCTCAAGTCTTGAATTTACAAAGAATAACTTAATTCAAATTGTTGGTGTCA
AGGAAGCCAATATCGAAGTAGTGGAGGTATCGACAGCTCCTGAGGGCACTGCTGAAGGAACTGTTGTGGATCAAAGTCCA
AAACTAGGTGAGAAAGTTGATCTAAGTACGACACGTATAAAGATTTCTATTTATAAACCAAAAACTCCACCATCATCTTC
TTCGGTTCCGTCTTCGAGCCAGCGTAACTCTAACAGGGCAGATAATACGGTGCCATCTCAAAGTCCATCGACACCATCTT
CGTCTACACCAACTCATGTGGACGAACACAACACAGATAACTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(439-505)

PASTA domain (PASTA)

(370-432)

PASTA domain (PASTA)

(510-579)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

79.392

94.418

0.75
  stkP Streptococcus pneumoniae D39

79.054

94.418

0.746
  stkP Streptococcus pneumoniae R6

79.054

94.418

0.746
  stkP Streptococcus pneumoniae Rx1

78.885

94.418

0.745
  pknB Streptococcus mutans UA159

56.131

92.344

0.518
  stkP/pknB Streptococcus salivarius strain HSISS4

58.077

82.935

0.482