Detailed information NTG0886515

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: RRU92_RS02350
• Genome accession: NZ_CP135436
• Coordinates: 461436..463589 (+)
• Length: 717 a.a.
• NCBI ID: WP_315640245.1
• Uniprot ID: A0AA96S489
• Organism: Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 456436..468589

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RRU92_RS02295 (RRU92_02295)	recO	456699..457469 (+)	771	WP_311522407.1	DNA repair protein RecO	-
RRU92_RS02300 (RRU92_02300)	plsX	457466..458458 (+)	993	WP_311522408.1	phosphate acyltransferase PlsX	-
RRU92_RS02305 (RRU92_02305)	-	458464..458700 (+)	237	WP_311522409.1	acyl carrier protein	-
RRU92_RS02310 (RRU92_02310)	-	459148..459291 (+)	144	WP_075229712.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
RRU92_RS02315 (RRU92_02315)	-	459309..459458 (+)	150	WP_311522410.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
RRU92_RS02320 (RRU92_02320)	-	459471..459647 (+)	177	WP_000793176.1	hypothetical protein	-
RRU92_RS02325 (RRU92_02325)	-	459856..460011 (+)	156	WP_162837517.1	hypothetical protein	-
RRU92_RS02335 (RRU92_02335)	-	460329..460517 (+)	189	Protein_441	hypothetical protein	-
RRU92_RS02340 (RRU92_02340)	-	460542..460751 (+)	210	WP_315640242.1	bacteriocin immunity protein	-
RRU92_RS02345 (RRU92_02345)	-	460858..461094 (+)	237	WP_315640244.1	hypothetical protein	-
RRU92_RS02350 (RRU92_02350)	comA	461436..463589 (+)	2154	WP_315640245.1	peptide cleavage/export ABC transporter ComA	Regulator
RRU92_RS02355 (RRU92_02355)	comB	463602..464951 (+)	1350	WP_315640246.1	HlyD family secretion protein	Regulator
RRU92_RS02360 (RRU92_02360)	purC	465120..465827 (+)	708	WP_315640247.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80168.96 Da
• Isoelectric Point: 5.8355

>NTDB_id=886515 RRU92_RS02350 WP_315640245.1 461436..463589(+) (comA) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MKFGKRHYRPQVDQMDCGVASLAMIFGYYGSYYSLAYLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMSLFDLPDV
TFPFVAHALKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVLIISVVLFSQNSNLFFMSLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSFL
EGDMDFKQVHYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGDISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGTHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=886515 RRU92_RS02350 WP_315640245.1 461436..463589(+) (comA) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGAAATTTGGGAAACGGCATTATCGTCCTCAGGTAGACCAGATGGACTGCGGTGTGGCTTCATTAGCCATGATCTTTGG
TTATTATGGAAGTTATTATTCTCTGGCTTACTTGCGAGAATTGGCCAAGACGACCATGGATGGGACTACAGCTTTAGGCT
TAGTCAAGGTTGCAGAGGAAATTGGTTTTGAGACGCGAGCAATAAAGGCGGACATGAGCTTGTTTGATTTGCCGGATGTA
ACCTTTCCTTTTGTGGCTCATGCGCTTAAGGAAGGAAAATTGCTCCATTATTATGTGGTGACTGGGCAGGATAAGGACAG
CATTCATATTGCCGATCCAGATCCTGGGGTAAAATTGACCAAGCTGCCACGTGAGCGTTTTGCGGAAGAATGGACGGGAG
TGACTCTGTTTATGGCACCTAGTCCAGACTATAAGCCTCATAAGGATCAGAAGAATGGCCTGCTATCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGTTTGATTGCCAATATAGTTTTGGCAACACTCTTGGTCACCTTGATTAACATTGTGGGTTCTTA
TTATTTGCAATCTATCATTGATACCTATGTTCCAGATCAGATGCGTTCGACGCTGGGGATTATTTCTATTGGGCTGGTCA
TCGTCTATATTCTCCAGCAGATCTTGTCTTATGCTCAGGAATATCTCTTACTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTATCCTATATCAAGCATGTTTTTCACCTGCCTATGTCCTTTTTTGCGACACGTCGTACAGGGGAAATCGTGTC
TCGTTTCACGGATGCTAACAGTATTATCGATGCTCTGGCTTCGACTATTCTGTCAATTTTTTTGGATGTATCTACTGTCT
TGATTATTTCAGTAGTTCTATTTTCGCAGAATAGCAATCTTTTTTTCATGAGTTTACTAGCTCTTCCTATCTACACAGTG
ATTATCTTTGCTTTTATGAAGCCCTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCAGTTCTGTCTTCTTCTAT
CATTGAGGACATCAATGGCATTGAGACCATCAAGTCCTTAACTAGTGAAAGCTCCCGTTATCAAAAGATTGACAAGGAAT
TTGTGGATTATCTGAAAAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAAGTTGCCCATCTC
TTGCTCAATGTCGGCATTCTATGGATGGGGGCTGTTCTGGTTATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAACCGTCTGAATGAGGTTTATCTGGTAGCTTCTGAGTTTGAGGAGAAGAAAACAGTTGAGGATTTGAGCTTTCTA
GAAGGAGATATGGATTTCAAGCAGGTTCACTACAAATATGGCTATGGTCGAGATGTCTTATCGGATATCAATTTGACTAT
TCCGCAGGGTTCTAAGGTGGCTTTTGTGGGGATTTCGGGGTCAGGTAAGACGACCTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGATATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCTCTGCGCCAGTATATC
AACTACCTGCCTCAGCAACCCTATGTTTTCAATGGGACGATTTTGGAGAATCTTCTCCTTGGAGCTAAGGAGGGGACGAC
CCAGGAGGATATCTTGAGAGCAGTGGAGTTGGCTGAGATTCGGGAGGATATCGAGCGGATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGAGCGGGCATTTCAGGTGGGCAACGTCAGAGAATTGCTTTGGCGCGTGCTCTCTTGACCGATGCG
CCTGTCTTGATTTTGGATGAGGCGACCAGCAGTTTGGATATTTTGACCGAGAAGCGAATTGTCGATAATCTCATGGCTTT
AGACAAGACCTTGATTTTCATCGCCCACCGCTTGACCATTGCTGAGCGGACAGAGAAGGTTGTCGTTTTGGATCAGGGCA
AGATTGTCGAAGAAGGCACACATGCAGATTTGTTGGCTCAGGGTGGCTTTTACGCCCATCTAGTGAATAGTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	97.211	100	0.972
comA	Streptococcus pneumoniae Rx1	96.932	100	0.969
comA	Streptococcus pneumoniae D39	96.932	100	0.969
comA	Streptococcus pneumoniae R6	96.932	100	0.969
comA	Streptococcus mitis SK321	96.792	100	0.968
comA	Streptococcus pneumoniae TIGR4	96.513	100	0.965
comA	Streptococcus gordonii str. Challis substr. CH1	81.45	100	0.815
comA/nlmT	Streptococcus mutans UA159	65.132	100	0.651