Detailed information
Bioinformatically predicted
Overview
| Name | comYD | Type | Machinery gene |
| Locus tag | QN328_RS00540 | Genome accession | NZ_CP135102 |
| Coordinates | 101718..102131 (+) | Length | 137 a.a. |
| NCBI ID | WP_017646959.1 | Uniprot ID | - |
| Organism | Streptococcus agalactiae strain HU32/21 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 102992..147108 | 101718..102131 | flank | 861 |
Gene organization within MGE regions
Location: 101718..147108
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QN328_RS00540 (QN328_00540) | comYD | 101718..102131 (+) | 414 | WP_017646959.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| QN328_RS00545 (QN328_00545) | comGE | 102103..102402 (+) | 300 | WP_025195478.1 | competence type IV pilus minor pilin ComGE | - |
| QN328_RS00550 (QN328_00550) | comGF | 102356..102817 (+) | 462 | WP_001874060.1 | competence type IV pilus minor pilin ComGF | - |
| QN328_RS00555 (QN328_00555) | comGG | 102795..103166 (+) | 372 | WP_000601104.1 | competence type IV pilus minor pilin ComGG | - |
| QN328_RS00560 (QN328_00560) | comYH | 103281..104255 (+) | 975 | WP_410530968.1 | class I SAM-dependent methyltransferase | Machinery gene |
| QN328_RS00565 (QN328_00565) | - | 104287..105480 (+) | 1194 | WP_000047534.1 | acetate kinase | - |
| QN328_RS00570 (QN328_00570) | - | 105632..105838 (+) | 207 | WP_000798241.1 | helix-turn-helix transcriptional regulator | - |
| QN328_RS00575 (QN328_00575) | - | 105897..106034 (+) | 138 | WP_001865900.1 | hypothetical protein | - |
| QN328_RS00580 (QN328_00580) | - | 106075..106530 (+) | 456 | WP_000905673.1 | hypothetical protein | - |
| QN328_RS00585 (QN328_00585) | - | 106599..107264 (+) | 666 | WP_000008113.1 | CPBP family intramembrane glutamic endopeptidase | - |
| QN328_RS00590 (QN328_00590) | proC | 107285..108055 (-) | 771 | WP_001865901.1 | pyrroline-5-carboxylate reductase | - |
| QN328_RS00595 (QN328_00595) | pepA | 108125..109192 (-) | 1068 | WP_001281323.1 | glutamyl aminopeptidase | - |
| QN328_RS00600 (QN328_00600) | - | 109377..109616 (-) | 240 | WP_000660180.1 | hypothetical protein | - |
| QN328_RS00605 (QN328_00605) | - | 109777..110061 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| QN328_RS00610 (QN328_00610) | - | 110058..110381 (+) | 324 | WP_000602781.1 | thioredoxin family protein | - |
| QN328_RS00615 (QN328_00615) | ytpR | 110414..111040 (+) | 627 | WP_000578328.1 | YtpR family tRNA-binding protein | - |
| QN328_RS00620 (QN328_00620) | - | 111094..111810 (-) | 717 | WP_000186185.1 | class I SAM-dependent methyltransferase | - |
| QN328_RS00625 (QN328_00625) | ssbA | 111891..112286 (+) | 396 | WP_000282447.1 | single-stranded DNA-binding protein | Machinery gene |
| QN328_RS00630 (QN328_00630) | - | 112410..113054 (+) | 645 | WP_000416612.1 | HAD family hydrolase | - |
| QN328_RS00635 (QN328_00635) | - | 113081..114826 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| QN328_RS00640 (QN328_00640) | - | 114807..115547 (+) | 741 | WP_000697630.1 | LytR/AlgR family response regulator transcription factor | - |
| QN328_RS00645 (QN328_00645) | - | 115717..116172 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| QN328_RS00650 (QN328_00650) | lrgB | 116174..116902 (+) | 729 | WP_000421724.1 | antiholin-like protein LrgB | - |
| QN328_RS00655 (QN328_00655) | - | 117145..118773 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| QN328_RS00660 (QN328_00660) | - | 118886..119863 (+) | 978 | WP_000680645.1 | ABC transporter permease | - |
| QN328_RS00665 (QN328_00665) | - | 119860..120681 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| QN328_RS00670 (QN328_00670) | - | 120693..121496 (+) | 804 | WP_000140984.1 | ABC transporter ATP-binding protein | - |
| QN328_RS00675 (QN328_00675) | - | 121480..122106 (+) | 627 | WP_000171309.1 | ABC transporter ATP-binding protein | - |
| QN328_RS00680 (QN328_00680) | treP | 122389..124419 (+) | 2031 | WP_000434616.1 | PTS system trehalose-specific EIIBC component | - |
| QN328_RS00685 (QN328_00685) | treC | 124641..126266 (+) | 1626 | WP_000151017.1 | alpha,alpha-phosphotrehalase | - |
| QN328_RS00690 (QN328_00690) | - | 126482..128518 (+) | 2037 | WP_000228183.1 | BglG family transcription antiterminator | - |
| QN328_RS00695 (QN328_00695) | - | 128521..128805 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| QN328_RS00700 (QN328_00700) | - | 128818..130173 (+) | 1356 | WP_000677361.1 | PTS ascorbate transporter subunit IIC | - |
| QN328_RS00705 (QN328_00705) | - | 130176..131033 (+) | 858 | WP_000203489.1 | transketolase | - |
| QN328_RS00710 (QN328_00710) | - | 131030..131959 (+) | 930 | WP_001203821.1 | transketolase family protein | - |
| QN328_RS00715 (QN328_00715) | - | 132068..133327 (+) | 1260 | WP_001203068.1 | ferric reductase-like transmembrane domain-containing protein | - |
| QN328_RS00720 (QN328_00720) | rpsO | 133415..133684 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| QN328_RS00725 (QN328_00725) | pnp | 134065..136194 (+) | 2130 | WP_000043850.1 | polyribonucleotide nucleotidyltransferase | - |
| QN328_RS00730 (QN328_00730) | - | 136196..136948 (+) | 753 | WP_000204782.1 | SseB family protein | - |
| QN328_RS00735 (QN328_00735) | cysE | 136957..137541 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| QN328_RS00740 (QN328_00740) | - | 137551..137733 (+) | 183 | WP_000656476.1 | lipoprotein | - |
| QN328_RS00745 (QN328_00745) | cysS | 137730..139073 (+) | 1344 | WP_000591131.1 | cysteine--tRNA ligase | - |
| QN328_RS00750 (QN328_00750) | - | 139066..139452 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| QN328_RS00755 (QN328_00755) | rlmB | 139555..140310 (+) | 756 | WP_000178026.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| QN328_RS00760 (QN328_00760) | - | 140307..140825 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| QN328_RS00765 (QN328_00765) | - | 140918..141778 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| QN328_RS00770 (QN328_00770) | - | 142315..142434 (+) | 120 | Protein_128 | helix-turn-helix transcriptional regulator | - |
| QN328_RS00775 (QN328_00775) | rplM | 142659..143105 (+) | 447 | WP_001865567.1 | 50S ribosomal protein L13 | - |
| QN328_RS00780 (QN328_00780) | rpsI | 143126..143518 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| QN328_RS00785 (QN328_00785) | - | 143662..144816 (-) | 1155 | WP_410530729.1 | tyrosine-type recombinase/integrase | - |
| QN328_RS00790 (QN328_00790) | - | 144871..145389 (-) | 519 | WP_000181342.1 | helix-turn-helix domain-containing protein | - |
| QN328_RS00795 (QN328_00795) | - | 145536..145820 (+) | 285 | WP_001287945.1 | hypothetical protein | - |
| QN328_RS00800 (QN328_00800) | - | 145832..146686 (+) | 855 | WP_018368155.1 | phage replisome organizer N-terminal domain-containing protein | - |
| QN328_RS00805 (QN328_00805) | - | 146697..146987 (+) | 291 | WP_000158581.1 | DUF5962 family protein | - |
Sequence
Protein
Download Length: 137 a.a. Molecular weight: 15910.35 Da Isoelectric Point: 9.9787
>NTDB_id=885309 QN328_RS00540 WP_017646959.1 101718..102131(+) (comYD) [Streptococcus agalactiae strain HU32/21]
MVLRKFQVKAFTVLESLIALSVVAFMTLVFSTSFNNIFRQVEETIFFISFEHLYRDTQKLSAFGQKKQTLTISHNYLENT
YERLYLPKTVKVVKSDTLAFDANGGNSSLAKIQFECYRKTVTYQLYIGSGNYRKKEN
MVLRKFQVKAFTVLESLIALSVVAFMTLVFSTSFNNIFRQVEETIFFISFEHLYRDTQKLSAFGQKKQTLTISHNYLENT
YERLYLPKTVKVVKSDTLAFDANGGNSSLAKIQFECYRKTVTYQLYIGSGNYRKKEN
Nucleotide
Download Length: 414 bp
>NTDB_id=885309 QN328_RS00540 WP_017646959.1 101718..102131(+) (comYD) [Streptococcus agalactiae strain HU32/21]
ATGGTTCTCAGAAAATTTCAAGTTAAAGCATTTACTGTTTTGGAGAGCCTTATTGCATTATCAGTAGTGGCATTTATGAC
GTTAGTATTTTCAACATCATTTAATAATATTTTTAGGCAGGTTGAAGAAACAATTTTCTTCATATCCTTTGAACATCTTT
ATAGAGATACTCAGAAATTGAGTGCATTTGGTCAGAAGAAACAAACCCTTACAATCTCTCATAATTATCTCGAAAATACT
TATGAGAGACTTTATTTACCTAAAACTGTAAAAGTAGTCAAAAGTGACACACTTGCATTTGACGCTAATGGAGGGAATTC
AAGCTTGGCAAAAATTCAATTTGAATGTTATAGAAAAACTGTCACGTATCAATTATATATAGGAAGTGGTAACTATCGTA
AGAAAGAAAATTAG
ATGGTTCTCAGAAAATTTCAAGTTAAAGCATTTACTGTTTTGGAGAGCCTTATTGCATTATCAGTAGTGGCATTTATGAC
GTTAGTATTTTCAACATCATTTAATAATATTTTTAGGCAGGTTGAAGAAACAATTTTCTTCATATCCTTTGAACATCTTT
ATAGAGATACTCAGAAATTGAGTGCATTTGGTCAGAAGAAACAAACCCTTACAATCTCTCATAATTATCTCGAAAATACT
TATGAGAGACTTTATTTACCTAAAACTGTAAAAGTAGTCAAAAGTGACACACTTGCATTTGACGCTAATGGAGGGAATTC
AAGCTTGGCAAAAATTCAATTTGAATGTTATAGAAAAACTGTCACGTATCAATTATATATAGGAAGTGGTAACTATCGTA
AGAAAGAAAATTAG
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYD | Streptococcus mutans UA140 |
51.515 |
96.35 |
0.496 |
| comYD | Streptococcus mutans UA159 |
51.515 |
96.35 |
0.496 |
| comYD | Streptococcus gordonii str. Challis substr. CH1 |
46.667 |
98.54 |
0.46 |
| comGD/cglD | Streptococcus mitis NCTC 12261 |
40.299 |
97.81 |
0.394 |
| comGD/cglD | Streptococcus pneumoniae TIGR4 |
42.52 |
92.701 |
0.394 |
| comGD/cglD | Streptococcus mitis SK321 |
42.52 |
92.701 |
0.394 |
| comGD/cglD | Streptococcus pneumoniae Rx1 |
41.732 |
92.701 |
0.387 |
| comGD/cglD | Streptococcus pneumoniae D39 |
41.732 |
92.701 |
0.387 |
| comGD/cglD | Streptococcus pneumoniae R6 |
41.732 |
92.701 |
0.387 |