Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RMQ61_RS09705 Genome accession   NZ_CP135090
Coordinates   1990876..1991598 (-) Length   240 a.a.
NCBI ID   WP_002938171.1    Uniprot ID   A0A116M1G6
Organism   Streptococcus suis strain ID48908     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1985876..1996598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ61_RS09685 (RMQ61_09690) - 1985948..1987171 (-) 1224 WP_313920636.1 cysteine desulfurase -
  RMQ61_RS09690 (RMQ61_09695) sufD 1987175..1988437 (-) 1263 WP_313920638.1 Fe-S cluster assembly protein SufD -
  RMQ61_RS09695 (RMQ61_09700) sufC 1988454..1989227 (-) 774 WP_024376584.1 Fe-S cluster assembly ATPase SufC -
  RMQ61_RS09700 (RMQ61_09705) - 1989707..1990879 (-) 1173 WP_313926305.1 MraY family glycosyltransferase -
  RMQ61_RS09705 (RMQ61_09710) mecA 1990876..1991598 (-) 723 WP_002938171.1 adaptor protein MecA Regulator
  RMQ61_RS09710 (RMQ61_09715) - 1991726..1992562 (-) 837 WP_277697659.1 undecaprenyl-diphosphate phosphatase -
  RMQ61_RS09715 (RMQ61_09720) - 1992689..1994254 (+) 1566 WP_024393418.1 ABC transporter substrate-binding protein/permease -
  RMQ61_RS09720 (RMQ61_09725) - 1994247..1994990 (+) 744 WP_024398474.1 amino acid ABC transporter ATP-binding protein -
  RMQ61_RS09725 (RMQ61_09730) - 1995118..1995327 (-) 210 WP_009910800.1 hypothetical protein -
  RMQ61_RS09730 (RMQ61_09735) - 1995413..1996315 (-) 903 WP_002937414.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27973.51 Da        Isoelectric Point: 4.0497

>NTDB_id=885001 RMQ61_RS09705 WP_002938171.1 1990876..1991598(-) (mecA) [Streptococcus suis strain ID48908]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=885001 RMQ61_RS09705 WP_002938171.1 1990876..1991598(-) (mecA) [Streptococcus suis strain ID48908]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCTAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACATGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116M1G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471