Detailed information
Bioinformatically predicted
Overview
| Name | cclA/cilC | Type | Machinery gene |
| Locus tag | RMP67_RS09280 | Genome accession | NZ_CP135087 |
| Coordinates | 1892273..1892917 (+) | Length | 214 a.a. |
| NCBI ID | WP_313920417.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain ID26102 | ||
| Function | processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1892525..1918701 | 1892273..1892917 | flank | -392 |
Gene organization within MGE regions
Location: 1892273..1918701
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RMP67_RS09280 (RMP67_09280) | cclA/cilC | 1892273..1892917 (+) | 645 | WP_313920417.1 | prepilin peptidase | Machinery gene |
| RMP67_RS09285 (RMP67_09285) | - | 1893025..1894485 (+) | 1461 | WP_024382383.1 | nicotinate phosphoribosyltransferase | - |
| RMP67_RS09290 (RMP67_09290) | nadE | 1894498..1895322 (+) | 825 | WP_313920420.1 | ammonia-dependent NAD(+) synthetase | - |
| RMP67_RS09295 (RMP67_09295) | trpB | 1895364..1896539 (-) | 1176 | WP_313920422.1 | tryptophan synthase subunit beta | - |
| RMP67_RS09300 (RMP67_09300) | - | 1897359..1897886 (-) | 528 | WP_002942846.1 | VanZ family protein | - |
| RMP67_RS09305 (RMP67_09305) | rlmN | 1897883..1898995 (-) | 1113 | WP_313920424.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| RMP67_RS09310 (RMP67_09310) | - | 1899004..1899645 (-) | 642 | WP_014638483.1 | YutD-like domain-containing protein | - |
| RMP67_RS09315 (RMP67_09315) | sepM | 1899833..1900882 (-) | 1050 | WP_014638484.1 | SepM family pheromone-processing serine protease | Regulator |
| RMP67_RS09320 (RMP67_09320) | coaD | 1900869..1901357 (-) | 489 | WP_002939048.1 | pantetheine-phosphate adenylyltransferase | - |
| RMP67_RS09325 (RMP67_09325) | rsmD | 1901347..1901886 (-) | 540 | WP_014638485.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD | - |
| RMP67_RS09330 (RMP67_09330) | - | 1902185..1902907 (-) | 723 | WP_313920427.1 | serine protease | - |
| RMP67_RS09335 (RMP67_09335) | - | 1902964..1903350 (-) | 387 | WP_004194735.1 | rhodanese-like domain-containing protein | - |
| RMP67_RS09340 (RMP67_09340) | - | 1903350..1903568 (-) | 219 | WP_004194736.1 | YqgQ family protein | - |
| RMP67_RS09345 (RMP67_09345) | - | 1903628..1904227 (-) | 600 | WP_313920429.1 | response regulator transcription factor | - |
| RMP67_RS09350 (RMP67_09350) | - | 1904224..1905318 (-) | 1095 | WP_313920431.1 | histidine kinase | - |
| RMP67_RS09355 (RMP67_09355) | - | 1905330..1906058 (-) | 729 | WP_313920434.1 | ABC transporter permease | - |
| RMP67_RS09360 (RMP67_09360) | - | 1906055..1906933 (-) | 879 | WP_205026074.1 | ABC transporter ATP-binding protein | - |
| RMP67_RS09365 (RMP67_09365) | - | 1907084..1907602 (-) | 519 | WP_313920436.1 | Dps family protein | - |
| RMP67_RS09370 (RMP67_09370) | - | 1907807..1908019 (+) | 213 | WP_002942806.1 | CsbD family protein | - |
| RMP67_RS09375 (RMP67_09375) | - | 1908189..1908623 (+) | 435 | WP_313920439.1 | low molecular weight protein-tyrosine-phosphatase | - |
| RMP67_RS09380 (RMP67_09380) | - | 1908755..1909177 (+) | 423 | WP_029176244.1 | membrane protein | - |
| RMP67_RS09385 (RMP67_09385) | - | 1909167..1910966 (+) | 1800 | WP_313920442.1 | acyltransferase family protein | - |
| RMP67_RS09390 (RMP67_09390) | - | 1911190..1911843 (-) | 654 | WP_313920443.1 | phosphatase PAP2 family protein | - |
| RMP67_RS09395 (RMP67_09395) | - | 1911868..1912425 (-) | 558 | WP_009910581.1 | ECF transporter S component | - |
| RMP67_RS09400 (RMP67_09400) | - | 1912749..1913294 (-) | 546 | WP_014736238.1 | tRNA (cytidine(34)-2'-O)-methyltransferase | - |
| RMP67_RS09405 (RMP67_09405) | yidD | 1913861..1914100 (-) | 240 | WP_014638497.1 | membrane protein insertion efficiency factor YidD | - |
| RMP67_RS09410 (RMP67_09410) | - | 1914100..1914831 (-) | 732 | WP_024375836.1 | pseudouridine synthase | - |
| RMP67_RS09415 (RMP67_09415) | scpB | 1914821..1915390 (-) | 570 | WP_002939233.1 | SMC-Scp complex subunit ScpB | - |
| RMP67_RS09420 (RMP67_09420) | - | 1915374..1916093 (-) | 720 | WP_313920446.1 | segregation/condensation protein A | - |
| RMP67_RS09425 (RMP67_09425) | xerD | 1916093..1916824 (-) | 732 | WP_313920448.1 | site-specific tyrosine recombinase XerD | - |
| RMP67_RS09430 (RMP67_09430) | cbpB | 1916821..1917279 (-) | 459 | WP_012027618.1 | cyclic-di-AMP-binding protein CbpB | - |
| RMP67_RS09435 (RMP67_09435) | - | 1917276..1917803 (-) | 528 | WP_313920450.1 | metallophosphoesterase | - |
Sequence
Protein
Download Length: 214 a.a. Molecular weight: 24308.51 Da Isoelectric Point: 8.6606
>NTDB_id=884890 RMP67_RS09280 WP_313920417.1 1892273..1892917(+) (cclA/cilC) [Streptococcus suis strain ID26102]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPASHCNACKRRLKAWDLIPILSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LLVLLCHFHILTITETTLILAGLVLTIYDIKHQEYPFAVWLVFTFIALVLSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICRFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCI
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPASHCNACKRRLKAWDLIPILSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LLVLLCHFHILTITETTLILAGLVLTIYDIKHQEYPFAVWLVFTFIALVLSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICRFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCI
Nucleotide
Download Length: 645 bp
>NTDB_id=884890 RMP67_RS09280 WP_313920417.1 1892273..1892917(+) (cclA/cilC) [Streptococcus suis strain ID26102]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCAGCTAGTCACTGCAATGCTTGCAAACGACGGCTCAAGGCTTGGGATCTAATTCCTATTCTTTCCC
AGCTTTCCACAAAATCCAAGTGCCGTTACTGCAAGGCGAAAATTCCTTATTGGTATCTGGGACTAGAGTTCTTAGCTGGT
CTATTGGTCCTACTCTGCCATTTTCACATCCTAACCATAACCGAAACTACTCTTATCTTAGCCGGGCTGGTCTTGACCAT
TTACGACATCAAGCATCAGGAATATCCCTTCGCTGTCTGGCTTGTTTTTACTTTTATAGCTCTGGTACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTAGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTTTTTCTTTCAAGTATTCCTATCATTCTGTGCA
TCTAA
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCAGCTAGTCACTGCAATGCTTGCAAACGACGGCTCAAGGCTTGGGATCTAATTCCTATTCTTTCCC
AGCTTTCCACAAAATCCAAGTGCCGTTACTGCAAGGCGAAAATTCCTTATTGGTATCTGGGACTAGAGTTCTTAGCTGGT
CTATTGGTCCTACTCTGCCATTTTCACATCCTAACCATAACCGAAACTACTCTTATCTTAGCCGGGCTGGTCTTGACCAT
TTACGACATCAAGCATCAGGAATATCCCTTCGCTGTCTGGCTTGTTTTTACTTTTATAGCTCTGGTACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTAGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTTTTTCTTTCAAGTATTCCTATCATTCTGTGCA
TCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| cclA/cilC | Streptococcus mitis SK321 |
50 |
99.065 |
0.495 |
| cclA/cilC | Streptococcus pneumoniae Rx1 |
49.515 |
96.262 |
0.477 |
| cclA/cilC | Streptococcus pneumoniae D39 |
49.515 |
96.262 |
0.477 |
| cclA/cilC | Streptococcus pneumoniae R6 |
49.515 |
96.262 |
0.477 |
| cclA/cilC | Streptococcus pneumoniae TIGR4 |
48.113 |
99.065 |
0.477 |
| cclA/cilC | Streptococcus mitis NCTC 12261 |
46.226 |
99.065 |
0.458 |