Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RMQ62_RS07530 Genome accession   NZ_CP135065
Coordinates   1552457..1553179 (+) Length   240 a.a.
NCBI ID   WP_002938171.1    Uniprot ID   A0A116M1G6
Organism   Streptococcus suis strain ID24665     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1547457..1558179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ62_RS07505 (RMQ62_07505) - 1547745..1548647 (+) 903 WP_002942264.1 SPFH domain-containing protein -
  RMQ62_RS07510 (RMQ62_07510) - 1548733..1548942 (+) 210 WP_009910800.1 hypothetical protein -
  RMQ62_RS07515 (RMQ62_07515) - 1549066..1549809 (-) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  RMQ62_RS07520 (RMQ62_07520) - 1549802..1551367 (-) 1566 WP_172076201.1 ABC transporter substrate-binding protein/permease -
  RMQ62_RS07525 (RMQ62_07525) - 1551493..1552329 (+) 837 WP_014638628.1 undecaprenyl-diphosphate phosphatase -
  RMQ62_RS07530 (RMQ62_07530) mecA 1552457..1553179 (+) 723 WP_002938171.1 adaptor protein MecA Regulator
  RMQ62_RS07535 (RMQ62_07535) - 1553176..1554348 (+) 1173 WP_313741764.1 MraY family glycosyltransferase -
  RMQ62_RS07540 (RMQ62_07540) sufC 1554722..1555495 (+) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  RMQ62_RS07545 (RMQ62_07545) sufD 1555512..1556774 (+) 1263 WP_024406545.1 Fe-S cluster assembly protein SufD -
  RMQ62_RS07550 (RMQ62_07550) - 1556778..1558001 (+) 1224 WP_313681182.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27973.51 Da        Isoelectric Point: 4.0497

>NTDB_id=884739 RMQ62_RS07530 WP_002938171.1 1552457..1553179(+) (mecA) [Streptococcus suis strain ID24665]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=884739 RMQ62_RS07530 WP_002938171.1 1552457..1553179(+) (mecA) [Streptococcus suis strain ID24665]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCGGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116M1G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471