Detailed information NTG0884679

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: RMQ63_RS05990
• Genome accession: NZ_CP135063
• Coordinates: 1250612..1251511 (+)
• Length: 299 a.a.
• NCBI ID: WP_015646238.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ID32563
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1245612..1256511

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMQ63_RS05960 (RMQ63_05960)	-	1245736..1246605 (-)	870	WP_313680565.1	cysteine ABC transporter substrate-binding protein	-
RMQ63_RS05965 (RMQ63_05965)	-	1246619..1247365 (-)	747	WP_044677099.1	amino acid ABC transporter ATP-binding protein	-
RMQ63_RS05970 (RMQ63_05970)	-	1247370..1248047 (-)	678	WP_044677097.1	amino acid ABC transporter permease	-
RMQ63_RS05975 (RMQ63_05975)	-	1248028..1248687 (-)	660	WP_044677125.1	amino acid ABC transporter permease	-
RMQ63_RS05980 (RMQ63_05980)	ruvB	1248815..1249816 (+)	1002	WP_004195448.1	Holliday junction branch migration DNA helicase RuvB	-
RMQ63_RS05985 (RMQ63_05985)	-	1249884..1250507 (+)	624	WP_024414287.1	HAD-IA family hydrolase	-
RMQ63_RS05990 (RMQ63_05990)	comR	1250612..1251511 (+)	900	WP_015646238.1	helix-turn-helix domain-containing protein	Regulator
RMQ63_RS05995 (RMQ63_05995)	-	1251719..1252939 (+)	1221	WP_313680566.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
RMQ63_RS06000 (RMQ63_06000)	-	1253130..1254653 (+)	1524	WP_313680567.1	quinol oxidase	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35175.03 Da
• Isoelectric Point: 4.5398

>NTDB_id=884679 RMQ63_RS05990 WP_015646238.1 1250612..1251511(+) (comR) [Streptococcus suis strain ID32563]
MNDKEFGQRVRQLRENASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVNKDRGEAEKHYLDAMLFAKLIENRELEQKIEEDWKVDNQ

Nucleotide

• Length: 900 bp

>NTDB_id=884679 RMQ63_RS05990 WP_015646238.1 1250612..1251511(+) (comR) [Streptococcus suis strain ID32563]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAAACGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTGCCAGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTCCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTGTCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTATGAACCAATACCAAAGATATTCGACAGTGTAGATAAAATTATACAGTCAACG
CAAGATTTTCAGAAAAAGCCAATTGTCAGTGTGTTGAAATGGAAGTATGCACTTTTTGTAAATAAGGATAGAGGTGAGGC
TGAAAAGCATTATCTAGATGCGATGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAGCAGAAGATTGAAGAAGATT
GGAAAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_31) (5-60)

• ComR tetratricopeptide (ComR_TPR) (73-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	92.977	100	0.93
comR	Streptococcus suis 05ZYH33	92.977	100	0.93
comR	Streptococcus suis D9	59.801	100	0.602
comR	Streptococcus mutans UA159	45.151	100	0.452
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	37.801	97.324	0.368
comR	Streptococcus pyogenes MGAS315	37.037	99.331	0.368