Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RMQ63_RS03975 Genome accession   NZ_CP135063
Coordinates   830984..831706 (-) Length   240 a.a.
NCBI ID   WP_313681185.1    Uniprot ID   -
Organism   Streptococcus suis strain ID32563     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 825984..836706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ63_RS03955 (RMQ63_03955) - 826162..827385 (-) 1224 WP_313681182.1 cysteine desulfurase -
  RMQ63_RS03960 (RMQ63_03960) sufD 827389..828651 (-) 1263 WP_024406545.1 Fe-S cluster assembly protein SufD -
  RMQ63_RS03965 (RMQ63_03965) sufC 828668..829441 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  RMQ63_RS03970 (RMQ63_03970) - 829815..830987 (-) 1173 WP_313681184.1 MraY family glycosyltransferase -
  RMQ63_RS03975 (RMQ63_03975) mecA 830984..831706 (-) 723 WP_313681185.1 adaptor protein MecA Regulator
  RMQ63_RS03980 (RMQ63_03980) - 831834..832670 (-) 837 WP_014638628.1 undecaprenyl-diphosphate phosphatase -
  RMQ63_RS03985 (RMQ63_03985) - 832796..834361 (+) 1566 WP_024393418.1 ABC transporter substrate-binding protein/permease -
  RMQ63_RS03990 (RMQ63_03990) - 834354..835097 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  RMQ63_RS03995 (RMQ63_03995) - 835222..835431 (-) 210 WP_009910800.1 hypothetical protein -
  RMQ63_RS04000 (RMQ63_04000) - 835517..836419 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28007.53 Da        Isoelectric Point: 4.0497

>NTDB_id=884671 RMQ63_RS03975 WP_313681185.1 830984..831706(-) (mecA) [Streptococcus suis strain ID32563]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPFAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=884671 RMQ63_RS03975 WP_313681185.1 830984..831706(-) (mecA) [Streptococcus suis strain ID32563]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTAGACATCTTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACAATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGTTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471