Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RJW49_RS08785 Genome accession   NZ_CP134477
Coordinates   1730009..1730731 (-) Length   240 a.a.
NCBI ID   WP_311048031.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1725009..1735731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS08765 (RJW49_08765) - 1725011..1726234 (-) 1224 WP_014736357.1 cysteine desulfurase -
  RJW49_RS08770 (RJW49_08770) sufD 1726238..1727500 (-) 1263 WP_024405299.1 Fe-S cluster assembly protein SufD -
  RJW49_RS08775 (RJW49_08775) sufC 1727517..1728290 (-) 774 WP_014736359.1 Fe-S cluster assembly ATPase SufC -
  RJW49_RS08780 (RJW49_08780) - 1728840..1730012 (-) 1173 WP_014736360.1 glycosyltransferase family 4 protein -
  RJW49_RS08785 (RJW49_08785) mecA 1730009..1730731 (-) 723 WP_311048031.1 adaptor protein MecA Regulator
  RJW49_RS08790 (RJW49_08790) - 1730859..1731695 (-) 837 WP_311048032.1 undecaprenyl-diphosphate phosphatase -
  RJW49_RS08795 (RJW49_08795) - 1731822..1733387 (+) 1566 WP_074393492.1 ABC transporter substrate-binding protein/permease -
  RJW49_RS08800 (RJW49_08800) - 1733380..1734123 (+) 744 WP_014736363.1 amino acid ABC transporter ATP-binding protein -
  RJW49_RS08805 (RJW49_08805) - 1734247..1734456 (-) 210 WP_009910800.1 hypothetical protein -
  RJW49_RS08810 (RJW49_08810) - 1734542..1735444 (-) 903 WP_002937414.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27990.50 Da        Isoelectric Point: 4.0497

>NTDB_id=880232 RJW49_RS08785 WP_311048031.1 1730009..1730731(-) (mecA) [Streptococcus suis strain NLS40]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYSVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=880232 RJW49_RS08785 WP_311048031.1 1730009..1730731(-) (mecA) [Streptococcus suis strain NLS40]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTACACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGTTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCTGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATTCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
TAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATTGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.917

100

0.479
  mecA Streptococcus thermophilus LMG 18311

47.5

100

0.475