Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   RJW49_RS05155 Genome accession   NZ_CP134477
Coordinates   974310..974981 (+) Length   223 a.a.
NCBI ID   WP_074393444.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   repress competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 972149..973351 974310..974981 flank 959


Gene organization within MGE regions


Location: 972149..974981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS05145 (RJW49_05145) - 972149..973351 (-) 1203 WP_311048118.1 IS110 family transposase -
  RJW49_RS05150 (RJW49_05150) - 973736..974116 (+) 381 WP_012027076.1 hypothetical protein -
  RJW49_RS05155 (RJW49_05155) ciaR 974310..974981 (+) 672 WP_074393444.1 response regulator transcription factor Regulator

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25275.98 Da        Isoelectric Point: 4.2132

>NTDB_id=880215 RJW49_RS05155 WP_074393444.1 974310..974981(+) (ciaR) [Streptococcus suis strain NLS40]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEDGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=880215 RJW49_RS05155 WP_074393444.1 974310..974981(+) (ciaR) [Streptococcus suis strain NLS40]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGATGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT
TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.686

100

0.897
  ciaR Streptococcus pneumoniae Rx1

87.892

100

0.879
  ciaR Streptococcus pneumoniae D39

87.892

100

0.879
  ciaR Streptococcus pneumoniae R6

87.892

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.892

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.39
  vicR Streptococcus mutans UA159

35.043

100

0.368