Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   RJW55_RS08880 Genome accession   NZ_CP134473
Coordinates   1897726..1899720 (-) Length   664 a.a.
NCBI ID   WP_043027199.1    Uniprot ID   A0A116MDM6
Organism   Streptococcus suis strain TMW_SS028     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1892726..1904720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW55_RS08860 (RJW55_08860) - 1893405..1894046 (-) 642 WP_043025113.1 response regulator transcription factor -
  RJW55_RS08865 (RJW55_08865) - 1894018..1895034 (-) 1017 WP_043025112.1 sensor histidine kinase -
  RJW55_RS08870 (RJW55_08870) liaF 1895031..1895690 (-) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  RJW55_RS08875 (RJW55_08875) - 1896271..1897392 (-) 1122 WP_172073174.1 IS110 family transposase -
  RJW55_RS08880 (RJW55_08880) stkP 1897726..1899720 (-) 1995 WP_043027199.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RJW55_RS08885 (RJW55_08885) - 1899720..1900457 (-) 738 WP_043033584.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RJW55_RS08890 (RJW55_08890) rsmB 1900495..1901808 (-) 1314 WP_079395308.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  RJW55_RS08895 (RJW55_08895) fmt 1901795..1902733 (-) 939 WP_043025417.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71434.01 Da        Isoelectric Point: 6.5352

>NTDB_id=880177 RJW55_RS08880 WP_043027199.1 1897726..1899720(-) (stkP) [Streptococcus suis strain TMW_SS028]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGLIFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQTLGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGR

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=880177 RJW55_RS08880 WP_043027199.1 1897726..1899720(-) (stkP) [Streptococcus suis strain TMW_SS028]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGATATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGGTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGGTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGGATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAACGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACAGAT
AAGGGGCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATATTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTGTCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTTGTCATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCAAAAATTACCCTTTATGTTTCCAAAGGAGTAGCGCCACAAGT
TGTGCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCTGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCACGTAGTCAATTACAAACGCTAGGCGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTACTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGCACCAGTAGCGATTCCTCAACAGGAAGTTCCACCAGCACAAGTACTTCAACAGATAGCGGACGATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116MDM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.395

97.59

0.521
  stkP Streptococcus pneumoniae D39

53.241

97.59

0.52
  stkP Streptococcus pneumoniae R6

53.241

97.59

0.52
  stkP Streptococcus pneumoniae Rx1

53.086

97.59

0.518
  stkP/pknB Streptococcus salivarius strain HSISS4

52.65

88.102

0.464
  pknB Streptococcus mutans UA159

54.953

80.572

0.443