Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RJW56_RS09390 Genome accession   NZ_CP134472
Coordinates   1887145..1887855 (-) Length   236 a.a.
NCBI ID   WP_024394941.1    Uniprot ID   -
Organism   Streptococcus suis strain 1522228     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1882145..1892855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW56_RS09370 (RJW56_09370) - 1882235..1883458 (-) 1224 WP_024394943.1 cysteine desulfurase -
  RJW56_RS09375 (RJW56_09375) sufD 1883462..1884724 (-) 1263 WP_024394942.1 Fe-S cluster assembly protein SufD -
  RJW56_RS09380 (RJW56_09380) sufC 1884741..1885514 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  RJW56_RS09385 (RJW56_09385) - 1885976..1887148 (-) 1173 WP_024381051.1 glycosyltransferase family 4 protein -
  RJW56_RS09390 (RJW56_09390) mecA 1887145..1887855 (-) 711 WP_024394941.1 adaptor protein MecA Regulator
  RJW56_RS09395 (RJW56_09395) - 1887983..1888819 (-) 837 WP_002938173.1 undecaprenyl-diphosphate phosphatase -
  RJW56_RS09400 (RJW56_09400) - 1888946..1890511 (+) 1566 WP_024394234.1 ABC transporter substrate-binding protein/permease -
  RJW56_RS09405 (RJW56_09405) - 1890504..1891247 (+) 744 WP_024389055.1 amino acid ABC transporter ATP-binding protein -
  RJW56_RS09410 (RJW56_09410) - 1891374..1891583 (-) 210 WP_009910800.1 hypothetical protein -
  RJW56_RS09415 (RJW56_09415) - 1891669..1892571 (-) 903 WP_002937414.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27458.03 Da        Isoelectric Point: 4.0987

>NTDB_id=880128 RJW56_RS09390 WP_024394941.1 1887145..1887855(-) (mecA) [Streptococcus suis strain 1522228]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEADEEEQERYIYYILEFPTIEDLFTFVGT
VDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 711 bp        

>NTDB_id=880128 RJW56_RS09390 WP_024394941.1 1887145..1887855(-) (mecA) [Streptococcus suis strain 1522228]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGTTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAAGCAG
ATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACTTTTGTTGGTACG
GTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTATCAATGTAGAAAA
TCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGACCAGACCTGCTT
TACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

50.82

100

0.525
  mecA Streptococcus pneumoniae D39

49.59

100

0.513
  mecA Streptococcus pneumoniae R6

49.59

100

0.513
  mecA Streptococcus pneumoniae Rx1

49.59

100

0.513
  mecA Streptococcus pneumoniae TIGR4

49.59

100

0.513
  mecA Streptococcus thermophilus LMD-9

46.531

100

0.483
  mecA Streptococcus thermophilus LMG 18311

46.667

100

0.475