Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RIN70_RS02320 Genome accession   NZ_CP134147
Coordinates   439974..440711 (+) Length   245 a.a.
NCBI ID   WP_003004768.1    Uniprot ID   I1ZKF6
Organism   Streptococcus parasanguinis strain 30.8.10     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 434974..445711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIN70_RS02305 (RIN70_02305) - 435306..436868 (-) 1563 WP_313790655.1 ABC transporter substrate-binding protein/permease -
  RIN70_RS02310 (RIN70_02310) - 436986..438893 (+) 1908 WP_313790656.1 DUF2207 domain-containing protein -
  RIN70_RS02315 (RIN70_02315) - 439002..439838 (+) 837 WP_013904699.1 undecaprenyl-diphosphate phosphatase -
  RIN70_RS02320 (RIN70_02320) mecA 439974..440711 (+) 738 WP_003004768.1 adaptor protein MecA Regulator
  RIN70_RS02325 (RIN70_02325) - 440708..441865 (+) 1158 WP_070595575.1 glycosyltransferase family 4 protein -
  RIN70_RS02330 (RIN70_02330) sufC 442000..442770 (+) 771 WP_003004238.1 Fe-S cluster assembly ATPase SufC -
  RIN70_RS02335 (RIN70_02335) sufD 442837..444099 (+) 1263 WP_129824526.1 Fe-S cluster assembly protein SufD -
  RIN70_RS02340 (RIN70_02340) - 444109..445335 (+) 1227 WP_070674936.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28238.84 Da        Isoelectric Point: 4.0867

>NTDB_id=878848 RIN70_RS02320 WP_003004768.1 439974..440711(+) (mecA) [Streptococcus parasanguinis strain 30.8.10]
MKMKQISDSTIKITIQLEDLEERGMEIADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQQLDFEDLSDLPDMEELSRMTPDEFIKTLEKTISDKTKGDAEAIHHLEQEELRDNQEQDPTSEAPVSQYIYYILRFSNI
QQAVAFSKTVSFPVDTSELYKMGSDYYLTVLIDTEDQPNQYPTWLLAIIREYADDSEVTRAVLQEHGHLLMVSGAIENLK
KVASL

Nucleotide


Download         Length: 738 bp        

>NTDB_id=878848 RIN70_RS02320 WP_003004768.1 439974..440711(+) (mecA) [Streptococcus parasanguinis strain 30.8.10]
ATGAAGATGAAGCAAATTAGTGATTCAACAATTAAGATCACGATCCAACTAGAAGACTTAGAAGAACGTGGAATGGAAAT
TGCTGATTTCCTTGTCCCACAAGAAAAAACAGAAGAATTTTTCTACGCTATTTTGGATGAACTCGAAATGCCAGAAAGCT
TCCTGGATAGCGGGATGCTGAGTTTTCGTGTGACACCAAAACCAGACAAATTGGATGTTTTTGTTACCAAATCAAAAATT
GACCAACAATTGGATTTTGAGGATTTGTCAGATCTTCCTGATATGGAAGAGTTGTCGCGCATGACGCCAGATGAATTTAT
CAAAACCCTGGAAAAAACAATCTCTGATAAGACAAAAGGGGATGCAGAAGCCATTCACCATTTGGAACAAGAAGAGTTGC
GGGACAATCAAGAACAAGATCCTACATCTGAAGCACCAGTAAGTCAGTATATTTATTACATTTTGCGTTTTTCAAATATC
CAGCAAGCAGTTGCCTTTTCAAAAACGGTCAGCTTTCCAGTGGATACCTCTGAATTATACAAAATGGGATCTGATTATTA
TTTAACCGTCTTGATCGATACAGAGGATCAACCAAATCAATATCCAACCTGGTTACTTGCCATCATTCGGGAGTATGCGG
ATGATTCAGAAGTGACACGAGCTGTTCTGCAGGAACATGGTCACTTACTAATGGTGTCTGGTGCGATTGAGAATTTGAAG
AAAGTTGCTAGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I1ZKF6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.571

100

0.686
  mecA Streptococcus pneumoniae D39

68.571

100

0.686
  mecA Streptococcus pneumoniae R6

68.571

100

0.686
  mecA Streptococcus pneumoniae TIGR4

68.571

100

0.686
  mecA Streptococcus mutans UA159

49.798

100

0.502
  mecA Streptococcus thermophilus LMD-9

47.561

100

0.478
  mecA Streptococcus thermophilus LMG 18311

47.154

100

0.473