Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   RDV49_RS10005 Genome accession   NZ_CP133988
Coordinates   2056668..2058539 (-) Length   623 a.a.
NCBI ID   WP_003010327.1    Uniprot ID   A0AAX4AX06
Organism   Streptococcus parasanguinis strain B-1756     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2051668..2063539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS09980 (RDV49_09980) - 2052402..2052767 (-) 366 WP_023920312.1 S1 RNA-binding domain-containing protein -
  RDV49_RS09985 (RDV49_09985) - 2052769..2054169 (-) 1401 WP_037608300.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RDV49_RS09990 (RDV49_09990) - 2054214..2054846 (-) 633 WP_003010319.1 response regulator transcription factor -
  RDV49_RS09995 (RDV49_09995) - 2054843..2055859 (-) 1017 WP_003010322.1 sensor histidine kinase -
  RDV49_RS10000 (RDV49_10000) liaF 2055856..2056551 (-) 696 WP_003003865.1 cell wall-active antibiotics response protein LiaF -
  RDV49_RS10005 (RDV49_10005) stkP 2056668..2058539 (-) 1872 WP_003010327.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RDV49_RS10010 (RDV49_10010) - 2058536..2059276 (-) 741 WP_003010330.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RDV49_RS10015 (RDV49_10015) rsmB 2059298..2060611 (-) 1314 WP_003010333.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  RDV49_RS10020 (RDV49_10020) fmt 2060601..2061536 (-) 936 WP_003010335.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 68569.82 Da        Isoelectric Point: 6.0303

>NTDB_id=878187 RDV49_RS10005 WP_003010327.1 2056668..2058539(-) (stkP) [Streptococcus parasanguinis strain B-1756]
MIQIGKIFAGRYKIIQQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMAELDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTRGIIHRDLKPQNVLLTPDGTAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIREENKNVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSCLSYERRNEKKLIFEDQSKADTKTLPKVSPTPKTAPVPISEVRSEISSV
DPNRPLSDQQTMAPSKKPRRRLRARYKVLFFAIALVLAAFTFLLYMSPANKTVPDVSGKTIAEARAVIEGQDLQVGEEKE
EYSDSVAEGYVIRTNPNAGAQKKEQSRIDLIVSKGPNSFEMPNYVGETRAKAEEDLKNTYKVSSKMITIEEVETFDYAAG
TVLEQTPAPGEQYSLNSKTKIVLKVAKETTSIEMPNYVGSTYDFARSNLIEIYGIKEANIELRKTEHLPDGVVVSAGQIV
SQTPEVSSTVDINRTRIVLTVYEPKVMASSSTKASSSSDASSSSSAERSDTESSSSSATGGDS

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=878187 RDV49_RS10005 WP_003010327.1 2056668..2058539(-) (stkP) [Streptococcus parasanguinis strain B-1756]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCCAACAAATTGGACGCGGCGGGATGGCAGATGTTTA
TCTTGCGCGTGATTTGATTTTGGATGGGGAAGAAGTTGCAGTCAAGGTACTGCGTACGAATTACCAGACGGATCCCATTG
CAGTTGCGCGTTTTCAGCGTGAAGCAAAGGCGATGGCAGAGCTGGACCATCCAAATATCGTTCGGATTACAGACATTGGC
GAAGAAGAAGGACAACAATACCTTGCAATGGAATATGTTGCAGGTTTAGACTTGAAACGCTATATCAAAGAAAATGCTCC
TTTATCAAATGAAGAAGCTGTTCGTTTGATGGGGCAGATCCTTCTAGCTATGCGTCTTGCCCATACGCGTGGCATTATCC
ATAGAGATTTAAAACCACAGAATGTTCTCTTGACACCAGATGGAACAGCAAAAGTTTCAGACTTTGGGATTGCAGTGGCC
TTCGCAGAGACTAGTTTGACTCAGACCAACTCGATGTTGGGGTCGGTTCATTATTTGTCCCCTGAGCAGGCGCGCGGTTC
AAAAGCTACGGTGCAAAGTGACATCTACGCGATGGGGATCATTTTCTATGAGATGTTGACAGGACACATTCCTTATGATG
GAGATAGTGCAGTTACAATCGCTTTGCAGCATTTTCAAAAGCCACTCCCATCTATTCGGGAAGAGAATAAGAATGTTCCA
CAAGCTTTAGAAAATGTGGTGATCAAAGCGACCGCTAAAAAACTGACGGATCGCTATAAATCAGTGGCAGAGATGTATGT
GGACCTTTCAAGTTGCTTGTCCTACGAGAGAAGAAATGAGAAAAAACTGATTTTTGAAGATCAATCGAAAGCTGATACAA
AGACTCTTCCAAAAGTGAGTCCAACTCCAAAGACGGCTCCTGTTCCAATCTCTGAGGTACGCAGTGAAATCAGTTCGGTA
GATCCTAATCGACCATTATCTGACCAGCAGACAATGGCACCAAGTAAAAAGCCAAGAAGACGCTTGCGGGCGCGCTACAA
GGTCTTGTTTTTTGCCATTGCCCTAGTTCTTGCAGCCTTTACTTTCTTGTTGTATATGAGCCCAGCCAATAAAACAGTTC
CAGATGTTTCCGGCAAAACCATTGCCGAAGCTAGAGCGGTTATTGAGGGACAAGACCTTCAAGTCGGTGAAGAGAAAGAA
GAGTACAGTGATTCGGTTGCAGAAGGCTATGTCATTCGGACCAATCCAAATGCAGGTGCTCAAAAGAAAGAACAAAGTCG
CATTGATTTGATTGTTTCAAAAGGTCCAAATAGTTTTGAAATGCCAAACTATGTAGGAGAAACACGAGCTAAAGCAGAGG
AAGATCTGAAAAATACTTATAAAGTATCAAGCAAAATGATCACGATTGAAGAAGTTGAGACCTTCGATTATGCTGCAGGG
ACAGTTCTTGAACAAACCCCAGCTCCAGGAGAGCAATATTCTCTGAATTCAAAAACCAAGATTGTTTTGAAAGTAGCGAA
AGAAACGACTTCAATTGAAATGCCAAACTATGTTGGATCAACTTATGATTTTGCTAGAAGTAATTTGATTGAGATCTATG
GTATTAAAGAAGCCAATATCGAATTAAGAAAAACGGAACATCTCCCTGATGGGGTAGTTGTTTCTGCCGGTCAAATTGTC
AGTCAAACTCCAGAAGTTTCGAGTACGGTGGATATTAACCGAACACGAATTGTTTTGACTGTATATGAGCCTAAAGTGAT
GGCTTCTTCAAGTACGAAAGCCTCATCAAGTTCAGATGCATCTAGTTCATCCTCTGCTGAACGATCAGATACAGAAAGCT
CCAGCAGTAGTGCAACTGGTGGAGATTCATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-245)

PASTA domain (PASTA)

(440-507)

PASTA domain (PASTA)

(512-582)

PASTA domain (PASTA)

(372-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

62.669

95.024

0.596
  stkP Streptococcus pneumoniae D39

62.5

95.024

0.594
  stkP Streptococcus pneumoniae R6

62.5

95.024

0.594
  stkP Streptococcus pneumoniae Rx1

62.331

95.024

0.592
  pknB Streptococcus mutans UA159

58.932

87.159

0.514
  stkP/pknB Streptococcus salivarius strain HSISS4

54.344

94.222

0.512