Detailed information NTG0878177

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: RDV49_RS09005
• Genome accession: NZ_CP133988
• Coordinates: 1874381..1876627 (-)
• Length: 748 a.a.
• NCBI ID: WP_003006329.1
• Uniprot ID: A0AAX4AX07
• Organism: Streptococcus parasanguinis strain B-1756
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1869381..1881627

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV49_RS08985 (RDV49_08985)	-	1870268..1871740 (-)	1473	WP_003006339.1	helicase HerA-like domain-containing protein	-
RDV49_RS08990 (RDV49_08990)	sodA	1871951..1872556 (-)	606	WP_003006336.1	superoxide dismutase SodA	-
RDV49_RS08995 (RDV49_08995)	holA	1872645..1873679 (-)	1035	WP_003006333.1	DNA polymerase III subunit delta	-
RDV49_RS09000 (RDV49_09000)	-	1873703..1874305 (-)	603	WP_003006331.1	DUF805 domain-containing protein	-
RDV49_RS09005 (RDV49_09005)	comEC/celB	1874381..1876627 (-)	2247	WP_003006329.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RDV49_RS09010 (RDV49_09010)	comEA/celA/cilE	1876608..1877276 (-)	669	WP_003006327.1	helix-hairpin-helix domain-containing protein	Machinery gene
RDV49_RS09015 (RDV49_09015)	-	1877343..1878089 (-)	747	WP_003006324.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
RDV49_RS09020 (RDV49_09020)	-	1878265..1880604 (+)	2340	WP_003006320.1	cation-translocating P-type ATPase	-
RDV49_RS09025 (RDV49_09025)	-	1880685..1881431 (+)	747	WP_003006317.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 85723.17 Da
• Isoelectric Point: 9.2946

>NTDB_id=878177 RDV49_RS09005 WP_003006329.1 1874381..1876627(-) (comEC/celB) [Streptococcus parasanguinis strain B-1756]
MLSRWIKDLPFSLVHLAFLLLWLYFSIYQPSWLSISGLVVVGVLALHHYKGDRSSLLGLALATLCFAAFFVFQRLQDHPV
QAESQPPSHLRLIPDTIKINGDKLSFRAKNQGRTYQAFYTLKSEKEKQQWQSQTHLLELTYKGVIEEPEGQRNFRGFDYR
SYLETQGIHYQIKIEAIQSAVPIQTWNVFDWLSQWRRQAIVWSKEHFPQPMNQYMTGLLFGYLDTDFEEMDQLYTSLGII
HLFALSGMQVGFFINGIRKALLRLGILQETVDIWMLPISLVYAGLTGFSVSVVRSLLQKILSQKGIRGMENMAMTLMILM
VLMPKFLLTAGGVLSCAYAFILTLVDTSSYSGLKKLLVESFWISLGILPLLTYYFSVFQPWSLPLTFLFSFLFDLVLLPG
LTVLFILSILKPLTIFNSFFLLIEECIRWISKLTSLPLVFGQPTGPALIALFLLLGILYDLRKQKKRRFLLIGMILLIFC
WTKHPLENEITMVDIGQGDSIFLRDWKGRTILIDVGGRVTFKSGEKWQERSQSANADQTLIPYLKSRGVGKLDALVLTHT
DQDHMGDMVEVAKQIPVKKVYVSPGSLTNSQFREKLKQLHSPIKVVQRGDQLPIFDHHLEVLSPDEVGDGKNDDSIVLYG
QFYQKRFLFTGDLEEAGEKKLLKNDPQLQVDVLKVGHHGSKGSSSDVFLDQLHPQLALISVGKKNRYQHPHKELLDRLEE
RSISYLRTDERGAIRLIGWDHWRVETVR

Nucleotide

• Length: 2247 bp

>NTDB_id=878177 RDV49_RS09005 WP_003006329.1 1874381..1876627(-) (comEC/celB) [Streptococcus parasanguinis strain B-1756]
ATGCTTTCACGGTGGATTAAAGACCTTCCTTTTTCGCTTGTCCATCTCGCCTTTTTGCTCCTATGGCTGTATTTTAGTAT
CTATCAACCATCTTGGCTTTCGATCAGCGGTCTAGTAGTAGTGGGAGTTTTAGCGCTTCATCACTATAAAGGGGATCGCT
CAAGTTTGCTAGGGCTTGCTTTAGCAACCCTTTGTTTTGCGGCCTTCTTTGTCTTTCAGCGACTACAGGATCATCCAGTA
CAAGCAGAAAGTCAGCCCCCATCCCACTTACGCCTGATTCCAGATACCATCAAGATCAATGGGGACAAGCTGTCTTTTCG
TGCTAAAAATCAGGGAAGGACCTACCAAGCCTTCTATACTTTAAAATCAGAAAAAGAAAAACAGCAGTGGCAAAGTCAAA
CCCACTTGCTGGAGTTGACATATAAAGGTGTCATAGAAGAACCAGAAGGGCAGCGAAATTTTAGAGGATTTGACTACCGG
TCTTATTTGGAAACACAGGGAATTCACTATCAAATAAAAATTGAAGCGATCCAATCTGCGGTTCCCATCCAAACGTGGAA
TGTTTTTGACTGGCTATCTCAATGGAGGCGCCAAGCCATTGTTTGGAGCAAGGAGCACTTTCCACAGCCGATGAACCAGT
ATATGACCGGCCTTCTTTTTGGTTATTTAGATACGGATTTTGAAGAGATGGATCAGCTTTACACGAGTTTGGGCATCATC
CATTTGTTCGCCTTATCTGGGATGCAGGTCGGCTTTTTCATCAATGGGATCCGGAAAGCTCTCTTACGTCTAGGAATCTT
GCAAGAGACAGTCGATATCTGGATGCTTCCAATTTCTTTGGTCTATGCTGGCTTGACAGGTTTTTCAGTTTCAGTGGTTC
GTAGTCTCTTGCAGAAGATCCTCTCTCAAAAGGGGATCCGAGGGATGGAGAATATGGCGATGACCTTGATGATCTTAATG
GTGCTCATGCCCAAGTTTCTTCTGACAGCTGGAGGGGTCTTGAGTTGTGCCTACGCCTTTATTTTGACCTTGGTAGATAC
CAGTTCTTATTCAGGACTTAAAAAGCTACTAGTGGAAAGTTTCTGGATTAGCCTGGGAATTTTGCCCCTTTTGACCTATT
ACTTTAGCGTCTTTCAACCCTGGTCACTCCCTTTAACCTTCCTCTTTTCTTTCTTATTTGACCTTGTCCTTCTTCCAGGT
TTAACGGTGCTATTTATCTTATCGATTCTAAAGCCCCTTACAATTTTTAACAGTTTCTTTCTTCTCATAGAGGAGTGTAT
TCGTTGGATTTCAAAGCTCACGTCGCTACCTTTGGTATTTGGTCAGCCGACGGGACCAGCTCTGATCGCTCTCTTCCTTC
TCTTAGGGATCTTGTATGATCTTCGAAAGCAAAAAAAACGTCGTTTCCTGTTAATAGGTATGATTCTACTCATCTTTTGT
TGGACCAAGCATCCTTTAGAAAATGAGATCACCATGGTGGATATCGGTCAAGGAGACAGTATCTTTTTACGCGATTGGAA
AGGAAGAACCATATTGATTGATGTCGGAGGACGTGTCACTTTTAAAAGTGGAGAAAAGTGGCAAGAGCGCAGTCAATCTG
CCAATGCGGATCAAACCTTGATTCCCTATCTCAAGAGTCGAGGTGTTGGAAAACTCGATGCTTTGGTCTTGACTCATACA
GACCAGGACCATATGGGCGATATGGTGGAGGTTGCCAAACAAATCCCAGTTAAAAAAGTGTATGTCAGTCCAGGTAGTCT
AACTAATTCTCAATTTAGAGAGAAATTGAAACAGCTTCATAGTCCGATTAAAGTAGTCCAGAGAGGAGATCAACTTCCTA
TTTTTGATCATCATCTAGAAGTCTTATCACCTGATGAAGTGGGGGATGGTAAAAATGATGATTCGATTGTCCTCTACGGG
CAGTTCTATCAGAAACGATTTTTGTTCACAGGTGATCTGGAAGAAGCCGGAGAGAAGAAACTATTGAAAAACGATCCACA
ATTACAAGTAGATGTCTTGAAAGTAGGCCACCACGGTTCTAAAGGTTCCTCTAGTGATGTGTTTTTAGATCAGTTACATC
CTCAGTTGGCCTTGATCTCTGTTGGAAAGAAAAATCGCTACCAACATCCCCATAAAGAATTGCTCGATCGTCTAGAGGAA
CGCTCTATTTCTTATCTTCGTACCGATGAAAGGGGAGCAATTCGCTTGATTGGGTGGGACCATTGGAGGGTAGAAACGGT
CCGCTAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (496-700)

• Domain of unknown function (DUF4131) (DUF4131) (29-178)

• Competence protein (Competence) (218-463)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.538	100	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.807	100	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.603	100	0.527
comEC/celB	Streptococcus pneumoniae Rx1	52.336	100	0.524
comEC/celB	Streptococcus pneumoniae D39	52.336	100	0.524
comEC/celB	Streptococcus pneumoniae R6	52.336	100	0.524
comEC	Lactococcus lactis subsp. cremoris KW2	47.263	100	0.473