Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RDV49_RS00085 Genome accession   NZ_CP133988
Coordinates   19640..20377 (-) Length   245 a.a.
NCBI ID   WP_003004768.1    Uniprot ID   I1ZKF6
Organism   Streptococcus parasanguinis strain B-1756     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 14640..25377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS00065 (RDV49_00065) - 15016..16242 (-) 1227 WP_003010274.1 cysteine desulfurase -
  RDV49_RS00070 (RDV49_00070) sufD 16252..17514 (-) 1263 WP_003010272.1 Fe-S cluster assembly protein SufD -
  RDV49_RS00075 (RDV49_00075) sufC 17581..18351 (-) 771 WP_003004238.1 Fe-S cluster assembly ATPase SufC -
  RDV49_RS00080 (RDV49_00080) - 18486..19643 (-) 1158 WP_003010268.1 glycosyltransferase family 4 protein -
  RDV49_RS00085 (RDV49_00085) mecA 19640..20377 (-) 738 WP_003004768.1 adaptor protein MecA Regulator
  RDV49_RS00090 (RDV49_00090) - 20513..21349 (-) 837 WP_003010265.1 undecaprenyl-diphosphate phosphatase -
  RDV49_RS00095 (RDV49_00095) - 21458..23365 (-) 1908 WP_037608297.1 DUF2207 domain-containing protein -
  RDV49_RS00100 (RDV49_00100) - 23483..25045 (+) 1563 WP_310744356.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28238.84 Da        Isoelectric Point: 4.0867

>NTDB_id=878136 RDV49_RS00085 WP_003004768.1 19640..20377(-) (mecA) [Streptococcus parasanguinis strain B-1756]
MKMKQISDSTIKITIQLEDLEERGMEIADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQQLDFEDLSDLPDMEELSRMTPDEFIKTLEKTISDKTKGDAEAIHHLEQEELRDNQEQDPTSEAPVSQYIYYILRFSNI
QQAVAFSKTVSFPVDTSELYKMGSDYYLTVLIDTEDQPNQYPTWLLAIIREYADDSEVTRAVLQEHGHLLMVSGAIENLK
KVASL

Nucleotide


Download         Length: 738 bp        

>NTDB_id=878136 RDV49_RS00085 WP_003004768.1 19640..20377(-) (mecA) [Streptococcus parasanguinis strain B-1756]
ATGAAGATGAAGCAAATTAGTGATTCAACTATTAAGATCACGATCCAACTAGAAGACTTAGAAGAACGTGGGATGGAAAT
TGCTGATTTCCTTGTCCCACAAGAAAAAACAGAAGAGTTTTTCTACGCCATTTTGGATGAACTCGAAATGCCAGAAAGCT
TCCTGGATAGCGGGATGCTTAGTTTTCGTGTGACACCAAAACCAGATAAACTGGATGTTTTTGTTACCAAATCAAAAATT
GACCAACAATTGGATTTTGAGGATTTGTCAGATCTTCCTGATATGGAAGAGTTGTCGCGCATGACGCCAGATGAATTTAT
CAAAACCTTGGAAAAAACGATTTCTGATAAGACAAAAGGGGATGCAGAAGCTATTCACCATTTGGAACAAGAAGAGTTAC
GGGACAATCAAGAACAAGATCCTACGTCTGAAGCACCAGTAAGTCAGTATATTTATTACATTTTGCGTTTTTCAAATATC
CAGCAAGCAGTTGCCTTTTCAAAAACGGTCAGCTTTCCAGTGGATACCTCTGAATTATACAAAATGGGATCTGATTATTA
TTTAACTGTCTTGATCGATACAGAGGATCAACCAAATCAATATCCAACCTGGTTACTTGCCATCATTCGGGAGTATGCGG
ATGATTCAGAAGTGACACGGGCCGTTCTACAGGAACATGGTCACTTACTAATGGTGTCTGGTGCGATTGAGAATTTGAAG
AAAGTTGCTAGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I1ZKF6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.571

100

0.686
  mecA Streptococcus pneumoniae D39

68.571

100

0.686
  mecA Streptococcus pneumoniae R6

68.571

100

0.686
  mecA Streptococcus pneumoniae TIGR4

68.571

100

0.686
  mecA Streptococcus mutans UA159

49.798

100

0.502
  mecA Streptococcus thermophilus LMD-9

47.561

100

0.478
  mecA Streptococcus thermophilus LMG 18311

47.154

100

0.473