Detailed information NTG0877765

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: RIM63_RS05125
• Genome accession: NZ_CP133952
• Coordinates: 1062563..1063408 (+)
• Length: 281 a.a.
• NCBI ID: WP_043983543.1
• Uniprot ID: A0A380JPG7
• Organism: Streptococcus equi subsp. zooepidemicus strain HT321
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1057563..1068408

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIM63_RS05110 (RIM63_05110)	-	1059058..1059690 (+)	633	WP_317585206.1	ABC transporter ATP-binding protein	-
RIM63_RS05115 (RIM63_05115)	ylqF	1060685..1061542 (+)	858	WP_206158626.1	ribosome biogenesis GTPase YlqF	-
RIM63_RS05120 (RIM63_05120)	-	1061532..1062305 (+)	774	WP_394854522.1	ribonuclease HII	-
RIM63_RS05125 (RIM63_05125)	dprA	1062563..1063408 (+)	846	WP_043983543.1	DNA-processing protein DprA	Machinery gene
RIM63_RS05130 (RIM63_05130)	topA	1063509..1065641 (+)	2133	WP_115250934.1	type I DNA topoisomerase	-
RIM63_RS05135 (RIM63_05135)	-	1065756..1066403 (+)	648	WP_037581215.1	SatD family protein	-
RIM63_RS05140 (RIM63_05140)	-	1066424..1067137 (+)	714	WP_301899120.1	DUF3307 domain-containing protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31334.24 Da
• Isoelectric Point: 8.8540

>NTDB_id=877765 RIM63_RS05125 WP_043983543.1 1062563..1063408(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain HT321]
MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCCKNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYP
LALREIYNPPVLLFYQGDLSLLEKPKLAVVGSRESSEIGTRSVYKIVKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVLVVEAKQRSGSLITCQLAMEEGR
DIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILSEYHYS

Nucleotide

• Length: 846 bp

>NTDB_id=877765 RIM63_RS05125 WP_043983543.1 1062563..1063408(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain HT321]
ATGAATAATTTTGAACTTTATAAATTAAAAAAGGCTGGGCTAACTAATTTAAATATTCTTAACCTGATTGACTACCAGCA
GCGTAATAACAAGTCTCTATCCCTTAGAGATATGGCAGTGGTTTCTTGCTGCAAAAATCCAGTTTTATTTATTGAGACCT
ACAAGCAATTAAATGTCGCCTTGTTAAAAAAGGAATTCAACCAGTTTCCGAGCTTATCTATCCTAGATAAGCAATACCCA
TTGGCCTTGAGGGAAATCTATAATCCTCCTGTTTTACTCTTTTATCAAGGTGATTTAAGCCTGTTAGAAAAGCCTAAGCT
GGCAGTCGTTGGCTCTAGAGAATCCAGTGAAATTGGGACGCGGTCTGTTTACAAAATCGTCAAAGAGCTTAAGAATCACT
TTGTCATTGTAAGTGGACTTGCTAGAGGTATTGATACCAGTGCTCATCTCGCTTGCTTGAAAGCAGGTGGGCAAACCATA
GCTGTTATCGGGACTGGCCTAGATCGCTACTATCCAAAGGAAAATCACCAGCTACAGGAGTTTTTATCTCAGCGTCATCT
CGTGCTCAGTGAATATGGGGCTGGAGAGGCCGCCTTGTCTTATCATTTCCCTGAAAGAAACCGTATTATCGCAGGTCTTA
GTCGAGGTGTCCTTGTTGTTGAGGCTAAGCAGCGCTCTGGCTCTTTGATTACCTGTCAGCTAGCTATGGAAGAGGGACGT
GATATTTTTGTCGTACCTGACAATATTCTTAATGGGACATCGGCGGGCTGTTTGAAGCTGATCAAAGATGGTGCCAGCTG
TGTCACTCATGGCAGAGACATTCTTTCAGAATACCACTATTCTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

3D structure

• AlphaFold DB: A0A380JPG7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	68.571	99.644	0.683
dprA/cilB/dalA	Streptococcus mitis SK321	58.929	99.644	0.587
dprA/cilB/dalA	Streptococcus pneumoniae D39	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus pneumoniae R6	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	58.214	99.644	0.58
dprA	Lactococcus lactis subsp. cremoris KW2	57.295	100	0.573
dprA	Bacillus subtilis subsp. subtilis str. 168	42.4	88.968	0.377