Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   RIM64_RS02435 Genome accession   NZ_CP133951
Coordinates   482094..483989 (+) Length   631 a.a.
NCBI ID   WP_012677494.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain JMC111     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 477094..488989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM64_RS02420 (RIM64_02420) fmt 479072..480007 (+) 936 WP_231148136.1 methionyl-tRNA formyltransferase -
  RIM64_RS02425 (RIM64_02425) rsmB 479997..481319 (+) 1323 WP_231148183.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  RIM64_RS02430 (RIM64_02430) - 481357..482097 (+) 741 WP_012516146.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RIM64_RS02435 (RIM64_02435) pknB 482094..483989 (+) 1896 WP_012677494.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RIM64_RS02440 (RIM64_02440) liaF 484122..484814 (+) 693 WP_012679994.1 cell wall-active antibiotics response protein LiaF -
  RIM64_RS02445 (RIM64_02445) - 484811..485815 (+) 1005 WP_012516143.1 sensor histidine kinase -
  RIM64_RS02450 (RIM64_02450) - 485808..486449 (+) 642 WP_043031305.1 response regulator transcription factor -
  RIM64_RS02455 (RIM64_02455) - 486483..487883 (+) 1401 WP_115266675.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RIM64_RS02460 (RIM64_02460) - 487883..488245 (+) 363 WP_012516140.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68568.74 Da        Isoelectric Point: 6.6073

>NTDB_id=877697 RIM64_RS02435 WP_012677494.1 482094..483989(+) (pknB) [Streptococcus equi subsp. zooepidemicus strain JMC111]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPNVP
QALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYNRSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAADAR
LEQTSQMDTLQKPQKKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEAGLKVGKVH
QIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDYQDVMTSLTETYGVPKSKIKIERIVTNEYPE
NTVISQSPSAGEKFNPAGKSKITLSVAVGDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSS
KAIVSGQTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQNDAVTTP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=877697 RIM64_RS02435 WP_012677494.1 482094..483989(+) (pknB) [Streptococcus equi subsp. zooepidemicus strain JMC111]
ATGATTCAGATTGGCAAGCTATTTGCTGGTCGTTATCGCATTCTAAAATCTATAGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAACGATTTGATTCTGGATAATGAGGACGTTGCCATTAAGGTCTTGCGGACCAATTATCAAACAGATCAGGTTG
CTGTTGCGCGTTTTCAAAGAGAAGCGCGAGCCATGGCTGAATTAAATCACCCCAATATTGTTGCCATTCGGGATATAGGC
GAGGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGCTCTGATTTGAAAAAATACATTCAGGATCATGCGCC
ATTATCTAACAATGAGGTGGTGAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCCCACCAAAAAGGAATTGTTC
ACAGGGATTTAAAGCCTCAAAACATTCTTTTGACCAAATCAGGTGTTGTTAAGGTTACAGATTTTGGGATTGCCGTTGCC
TTTGCAGAGACCAGTCTAACCCAGACAAATTCTATGCTAGGAAGTGTGCATTACCTCTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACGATTCAAAGTGATATTTACGCGATGGGAATTATGCTCTTTGAAATGCTAACAGGGCATATTCCTTATGATG
GCGATAGCGCTGTGACGATTGCTTTGCAGCATTTTCAAAAGCCGCTGCCCTCTATCATTGATGAAAATCCTAATGTGCCT
CAAGCCTTGGAGAACGTCGTTATTCGGGCTACTGCCAAAAAGCTAAGTGACCGTTATCGCTCGACCTTTGAGATGAGCAG
GGATTTGATGACAGCCCTTAGCTATAACCGCAGTCGTGAGCGTAAGGTTGTCTTTGATGATGTCGAAAGCACAAAGCCCT
TGCCAAAGGTAACACCGACTCCTGTAACAGCACCTAAGGTATCAAATGCTAGTCAGGCATCTGCGGCAGCTGATGCTAGA
CTTGAGCAGACTAGCCAGATGGATACTCTGCAAAAGCCTCAAAAAAAGAAAAAAAATGGGCGTTTTCTAGGAACACTCTT
AAAAATCTTGTTTTCCTTTTTTGTTGTTGGTGTGGCTCTTTTTGCTTATTTGGTCTTGACCAAGCCAACTACGGTTAAGG
TTCCTGATGTGACAGGCTCTAGTCTCAATGCTGCCAAGCAGGTCTTGGAGGAGGCGGGACTAAAGGTCGGTAAGGTCCAT
CAGATTGAAAGTGACACAGTTAGTGAGGATCAGGTGGTTAAGACAAATCCTCAAGCTGGCTCAGCTAAGCGAAAAGGCTC
CAGCGTTGACCTTTACCTTTCGATCGGAAATAAAGGCTTTGAGATGGAAAATTATAAGGGACAGGATTATCAAGATGTGA
TGACCAGTCTGACTGAGACCTATGGCGTACCAAAGTCAAAAATCAAGATTGAGCGTATCGTGACAAATGAATACCCTGAA
AACACCGTTATTAGCCAGTCTCCAAGCGCAGGAGAAAAATTTAACCCAGCTGGTAAATCTAAGATTACTCTCAGTGTAGC
AGTGGGTGATACGGTCATCATGCCAATGGTAACTGAGTACAGCTATGCAGACGCAGTCAATACACTAACAGCCCTAGGAA
TTGATGCCGCAAGAATCAAGGCCTATGTACCAAGCTCCAGCTCTCCGACAGGCTTTGTGCAGGTGAGCTCCCCAAGCTCA
AAGGCGATTGTCAGTGGGCAGACACCGTATTATGGTACCCAGATTAGCCTTTCTGAAAAGGGTGATATTAGCCTCTACCT
CTACCCTGAGGAGACACGTGCATCAAGCAGCTCATCGAGCTCTGATACCTCGGCTCCTAATCCATCAGCTGGAGATACAA
CAGACTCAAGCAGTCATACCGAATTAGGTCAAAATGACGCTGTTACAACACCGTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(512-588)

PASTA domain (PASTA)

(441-506)

Protein kinase domain (Pkinase)

(12-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.714

94.295

0.62
  stkP/pknB Streptococcus salivarius strain HSISS4

62.415

93.185

0.582
  stkP Streptococcus pneumoniae TIGR4

57.558

81.775

0.471
  stkP Streptococcus pneumoniae D39

57.171

81.775

0.468
  stkP Streptococcus pneumoniae R6

57.171

81.775

0.468
  stkP Streptococcus pneumoniae Rx1

56.977

81.775

0.466