Detailed information NTG0876882

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: RF668_RS06425
• Genome accession: NZ_CP133787
• Coordinates: 1234580..1236790 (+)
• Length: 736 a.a.
• NCBI ID: WP_043735587.1
• Uniprot ID: A0AAX4AL50
• Organism: Lactococcus cremoris strain KCKM 0438
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1229580..1241790

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RF668_RS06400 (RF668_06400)	-	1230414..1230974 (+)	561	WP_011835699.1	GNAT family N-acetyltransferase	-
RF668_RS06405 (RF668_06405)	-	1231091..1231489 (+)	399	WP_043735595.1	hypothetical protein	-
RF668_RS06410 (RF668_06410)	-	1231595..1232527 (+)	933	WP_309559527.1	ABC transporter ATP-binding protein	-
RF668_RS06415 (RF668_06415)	-	1232524..1233885 (+)	1362	WP_043735590.1	ABC transporter permease	-
RF668_RS06420 (RF668_06420)	comEA	1233943..1234599 (+)	657	WP_043735588.1	helix-hairpin-helix domain-containing protein	Machinery gene
RF668_RS06425 (RF668_06425)	comEC	1234580..1236790 (+)	2211	WP_043735587.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RF668_RS06430 (RF668_06430)	-	1237074..1237850 (+)	777	WP_014572211.1	alpha/beta hydrolase family protein	-
RF668_RS06435 (RF668_06435)	-	1238033..1238248 (+)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
RF668_RS06440 (RF668_06440)	atpB	1238295..1239008 (+)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
RF668_RS06445 (RF668_06445)	atpF	1239023..1239529 (+)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
RF668_RS06450 (RF668_06450)	-	1239531..1240058 (+)	528	WP_043735583.1	F0F1 ATP synthase subunit delta	-
RF668_RS06455 (RF668_06455)	atpA	1240246..1241748 (+)	1503	WP_014572214.1	F0F1 ATP synthase subunit alpha	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84566.54 Da
• Isoelectric Point: 9.8548

>NTDB_id=876882 RF668_RS06425 WP_043735587.1 1234580..1236790(+) (comEC) [Lactococcus cremoris strain KCKM 0438]
MRFLLIKFPLIFLTYLVVLLYFCIFTYNLPLLILFICSILLALSRKYYLMIPILIVFSGFFLLINSLSIRDNENQPKNLS
KIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKKFYQNLSQNCQLSFTGNLEIPETQRNFNGFDDQKYLASQNI
YRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFGFLSKDFNQMSDIYSSLGIIHLFALSGMQVNF
FIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNIRLTSLDNIAVTTLVLMLISPKFLLTTGGQLT
LFYAFVISMLNHPFSNLNGLKKVLTESAVLSLCVLPLLIFDFHIFQPLSILLTIIFGFLFDFMLLPLLLCCFLISFLGFS
LNLNFIFQILEWLVHKVDLPLHYPFVLGKPSSLELIVLFVLIGLFVDSFFHKKRKFFLVGFIFLFFFITKNPMRSSITAV
DIGQGDSIFLQDKFNKENILIDTGGQLALPQKNWQKAQTQSNADKTLIPYLESMGVAHIDQLILTRTDADHVGDFLSLAD
KIKIREIWVSPGELTNSSFVEKLKKAKIPIHVSKVGDKIPIFDSFLQVLSNGYTKKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKKLLQNYPKLQVDVLKVGHHGSKTSSSPEFIKEIHPKLALISVGKANRYGHPNQETLETLAKNQVKTLRTDQKGA
IKLTEVNQQWQIKTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=876882 RF668_RS06425 WP_043735587.1 1234580..1236790(+) (comEC) [Lactococcus cremoris strain KCKM 0438]
ATGAGATTTCTATTGATTAAATTTCCCCTGATTTTTCTAACTTATCTTGTTGTGCTCCTTTATTTTTGTATCTTTACTTA
CAATTTACCCTTGCTTATTTTATTTATTTGCTCAATTTTACTAGCTTTATCCAGAAAATATTATCTAATGATTCCGATAT
TAATTGTTTTTTCTGGATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACCAAAAAATCTCTCA
AAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGAATGGACAAAAATA
TCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAAAATTTTATCAGAACTTAAGTCAAAATTGTCAGTTAAGTTTCA
CAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAGCTAGTCAAAATATC
TATCGACAGATTACCATTCAGCAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTTTAAGGCGAAAGGC
AATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGCTTTTTAAGTAAGG
ATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAATGCAAGTAAATTTT
TTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTCAAATTCCATTTTC
TATTTTTTATGCTTTTATGACGGGATTATCAGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATTCGTCTGACTTCTT
TGGATAATATCGCAGTGACGACATTAGTTTTGATGCTTATAAGTCCAAAATTTTTACTGACGACTGGTGGTCAGCTTACC
TTGTTTTATGCTTTTGTCATTTCGATGCTTAACCATCCTTTTTCTAATTTAAATGGATTGAAAAAAGTGCTGACAGAATC
AGCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTTCATATTTTTCAACCTCTTTCAATATTATTAACAA
TTATATTTGGTTTTCTTTTTGATTTTATGCTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATTTTTGGGATTTTCG
CTCAATTTAAACTTTATTTTTCAAATTCTAGAATGGCTAGTTCATAAAGTTGATTTACCCTTACATTACCCCTTTGTTTT
GGGGAAACCTAGTTCACTCGAATTAATTGTTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTTTTTCATAAAAAAA
GGAAATTTTTTTTAGTTGGATTTATATTTTTATTTTTTTTCATCACTAAAAATCCAATGAGATCAAGCATTACAGCGGTT
GATATCGGACAAGGCGATAGTATTTTTCTACAAGATAAGTTTAATAAAGAAAACATTCTGATTGATACTGGGGGACAACT
TGCTCTTCCTCAAAAAAATTGGCAAAAAGCGCAGACGCAATCGAATGCTGACAAAACGCTTATTCCATATTTAGAATCCA
TGGGGGTGGCTCATATTGACCAACTTATTCTGACTCGTACAGATGCTGACCATGTTGGCGATTTCTTGTCCTTAGCTGAT
AAAATAAAAATAAGAGAAATCTGGGTCAGTCCGGGAGAATTAACCAACAGTAGTTTTGTGGAAAAATTAAAAAAAGCAAA
AATTCCGATTCATGTTAGTAAAGTTGGGGATAAAATTCCGATTTTTGATAGTTTTCTTCAAGTTTTATCAAATGGTTACA
CTAAAAAAGGTGATAATAATGATTCCATAGTGACTTATGGAAACTTTTACCATACAAAATTTCTTTTTACAGGAGATTTG
GAACAAGAAGGAGAAAAAAAGCTTCTACAAAATTATCCCAAATTACAGGTAGATGTGTTAAAAGTGGGGCATCATGGCAG
TAAAACAAGTTCAAGTCCAGAATTCATCAAAGAGATACATCCTAAACTTGCACTAATCTCGGTTGGAAAAGCTAATCGCT
ATGGTCATCCCAATCAAGAAACTTTAGAAACCCTAGCCAAAAATCAGGTAAAGACACTCAGAACTGACCAAAAAGGGGCA
ATAAAATTAACAGAAGTAAATCAGCAGTGGCAAATCAAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (206-446)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Domain of unknown function (DUF4131) (DUF4131) (29-171)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	97.826	100	0.978
comEC/celB	Streptococcus mitis SK321	45.749	100	0.461
comEC/celB	Streptococcus mitis NCTC 12261	44.73	100	0.45
comEC/celB	Streptococcus pneumoniae TIGR4	44.669	100	0.45
comEC/celB	Streptococcus pneumoniae Rx1	43.995	100	0.443
comEC/celB	Streptococcus pneumoniae D39	43.995	100	0.443
comEC/celB	Streptococcus pneumoniae R6	43.995	100	0.443