Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   RF668_RS04095 Genome accession   NZ_CP133787
Coordinates   808530..809753 (-) Length   407 a.a.
NCBI ID   WP_043736154.1    Uniprot ID   A0AAX4AJK1
Organism   Lactococcus cremoris strain KCKM 0438     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 803530..814753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RF668_RS04070 (RF668_04070) - 803644..804396 (+) 753 WP_043736147.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  RF668_RS04075 (RF668_04075) - 804453..805457 (-) 1005 WP_043736149.1 hypothetical protein -
  RF668_RS04080 (RF668_04080) - 805601..805825 (-) 225 WP_003130579.1 YkuJ family protein -
  RF668_RS04085 (RF668_04085) - 805933..807273 (-) 1341 WP_043736152.1 glycosyltransferase family 4 protein -
  RF668_RS04090 (RF668_04090) - 807411..808409 (-) 999 WP_011836059.1 glycosyltransferase family 4 protein -
  RF668_RS04095 (RF668_04095) htrA 808530..809753 (-) 1224 WP_043736154.1 S1C family serine protease Regulator
  RF668_RS04100 (RF668_04100) rlmH 810129..810608 (+) 480 WP_011677194.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  RF668_RS04105 (RF668_04105) - 810626..811324 (+) 699 WP_043736156.1 DNA alkylation repair protein -
  RF668_RS04110 (RF668_04110) yajC 811419..811751 (+) 333 WP_043736159.1 preprotein translocase subunit YajC -
  RF668_RS04115 (RF668_04115) - 812102..812836 (+) 735 WP_011836054.1 isoprenyl transferase -
  RF668_RS04120 (RF668_04120) - 812836..813639 (+) 804 WP_011677190.1 phosphatidate cytidylyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41555.02 Da        Isoelectric Point: 5.3802

>NTDB_id=876864 RF668_RS04095 WP_043736154.1 808530..809753(-) (htrA) [Lactococcus cremoris strain KCKM 0438]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYDEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGVVVYSVQAGLPAATAGLKAGDVITKVGDTAITSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=876864 RF668_RS04095 WP_043736154.1 808530..809753(-) (htrA) [Lactococcus cremoris strain KCKM 0438]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACGACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTTACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACGGCTTGCAACTTTCCAGTGAGGG
TTCTGGTGTTATTTACAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCCGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
GGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCTGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACTGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCTTTAGGTATCCGTATGGTTGACTTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGAGTGGTTGTCTACTCTGTTCAAGCAGGTCTTCCTGCTGCCACAGCTGGTCTGAAAGCTGGCGATGTGAT
AACGAAAGTAGGAGATACTGCTATTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(250-395)

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

PDZ domain (PDZ_2)

(295-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

55.385

95.823

0.531
  htrA Streptococcus mitis NCTC 12261

56.136

94.103

0.528
  htrA Streptococcus pneumoniae R6

58.43

84.521

0.494
  htrA Streptococcus pneumoniae TIGR4

58.43

84.521

0.494
  htrA Streptococcus pneumoniae D39

58.43

84.521

0.494
  htrA Streptococcus pneumoniae Rx1

58.43

84.521

0.494
  htrA Streptococcus mutans UA159

53.117

90.663

0.482