Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   RG903_RS03390 Genome accession   NZ_CP133759
Coordinates   675295..676656 (-) Length   453 a.a.
NCBI ID   WP_211218612.1    Uniprot ID   -
Organism   Thermithiobacillus tepidarius DSM 3134     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 670295..681656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG903_RS03365 (RG903_03355) - 671739..672746 (-) 1008 WP_028988552.1 class 1 fructose-bisphosphatase -
  RG903_RS03370 (RG903_03360) - 672746..672955 (-) 210 WP_028988551.1 DNA gyrase inhibitor YacG -
  RG903_RS03375 (RG903_03365) zapD 672970..673731 (-) 762 WP_028988550.1 cell division protein ZapD -
  RG903_RS03380 (RG903_03370) coaE 673736..674398 (-) 663 WP_051180643.1 dephospho-CoA kinase -
  RG903_RS03385 (RG903_03375) - 674403..675206 (-) 804 WP_028988549.1 prepilin peptidase -
  RG903_RS03390 (RG903_03380) pilR 675295..676656 (-) 1362 WP_211218612.1 sigma-54-dependent transcriptional regulator Regulator
  RG903_RS03395 (RG903_03385) - 676653..678362 (-) 1710 WP_051180642.1 two-component system sensor histidine kinase NtrB -
  RG903_RS03400 (RG903_03390) pilC 678376..679623 (-) 1248 WP_051180641.1 type II secretion system F family protein Machinery gene
  RG903_RS03405 (RG903_03395) pilB 679640..681361 (-) 1722 WP_028988546.1 type IV-A pilus assembly ATPase PilB Machinery gene

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 49525.95 Da        Isoelectric Point: 6.0330

>NTDB_id=876390 RG903_RS03390 WP_211218612.1 675295..676656(-) (pilR) [Thermithiobacillus tepidarius DSM 3134]
MNGSMEQNIRTLIVDDEPAIRELLAFTLEDMDLQVSVAATVREAKMQLEQGGIDFCLTDLRLPDGSGLEIVSEIQHHHPL
MPVAVITAYSSADSAVEAMKAGAFDYVSKPIEVNRLRQLARRAIQLLGPRVAEKAAVDPVVGEGPQILGVSPAITRVREQ
IQRLGRSMAPVHITGESGTGKELVARAIHAASPRAAAPFTPVNCGAIPENLMESEFFGYEKGAFTGATQRRAGLFEAANG
GTLFLDEVADLPLPMQVKLLRAIQERAIRPVGAHKEMPVDVRVISATHQDLAQLVAEKRFREDLYYRLNVIPLSVPPLRE
RREDIPVIAEMLLQRIAQRQGLGSLRLSPAALAWLTHYPFYGNVRELENLLERAAALHEGASIEPHDLQAPGTPPAESCA
APPNLDATIEATEGRILLDALERAQGVKTEAARLLGISFRSFRYRLKKLGLDQ

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=876390 RG903_RS03390 WP_211218612.1 675295..676656(-) (pilR) [Thermithiobacillus tepidarius DSM 3134]
ATGAACGGCAGCATGGAACAGAACATCCGCACCCTGATCGTGGACGACGAACCAGCCATCCGTGAGCTCCTGGCCTTCAC
CCTGGAGGACATGGACCTGCAGGTCAGCGTGGCCGCCACCGTGCGCGAGGCCAAGATGCAGCTCGAGCAGGGCGGCATCG
ATTTTTGCCTGACCGATCTGCGCCTGCCCGATGGCAGCGGCCTGGAAATCGTCTCCGAGATCCAGCACCACCACCCCCTC
ATGCCGGTGGCCGTGATCACGGCCTACTCCTCCGCCGACAGCGCGGTGGAGGCCATGAAAGCCGGGGCCTTCGACTACGT
TTCCAAGCCCATCGAGGTCAACCGCCTGCGGCAACTGGCCCGCCGCGCCATTCAGCTGCTCGGCCCCCGGGTGGCGGAAA
AGGCGGCGGTCGACCCGGTCGTCGGCGAAGGGCCGCAGATCCTCGGCGTCTCCCCGGCGATCACCCGCGTGCGTGAGCAA
ATCCAGCGCCTGGGCCGCAGCATGGCCCCGGTGCACATCACCGGCGAATCGGGTACCGGCAAGGAGCTGGTGGCCCGCGC
CATTCATGCCGCCAGCCCGCGCGCCGCGGCGCCTTTCACCCCGGTCAACTGCGGCGCTATCCCCGAAAACCTGATGGAGA
GCGAATTTTTCGGCTACGAAAAGGGTGCCTTCACCGGCGCGACCCAGCGCCGGGCCGGCCTCTTCGAGGCCGCCAACGGC
GGCACGCTCTTTCTGGACGAGGTGGCGGACCTGCCGCTGCCCATGCAGGTCAAGCTCCTGCGCGCCATCCAGGAGCGGGC
CATCCGGCCGGTTGGCGCCCACAAGGAGATGCCGGTGGACGTGCGCGTCATTTCCGCGACCCACCAGGACTTGGCGCAAT
TGGTGGCGGAAAAGCGCTTCCGCGAGGATCTCTACTACCGGCTCAACGTCATTCCCCTGTCCGTGCCGCCCCTGCGCGAG
CGCCGCGAGGACATCCCCGTCATCGCCGAGATGCTGCTGCAGCGCATTGCCCAGCGCCAGGGGCTCGGTTCCCTGCGGCT
CAGCCCCGCCGCCCTGGCTTGGCTGACCCACTACCCCTTCTACGGCAACGTGCGGGAGCTCGAAAACCTGCTGGAGCGCG
CCGCGGCCCTGCATGAAGGCGCCAGCATCGAACCCCATGACCTGCAGGCGCCCGGCACGCCGCCGGCCGAAAGCTGCGCG
GCGCCGCCCAACCTGGACGCCACCATCGAGGCCACCGAGGGCCGCATCCTCTTGGATGCCCTGGAACGCGCCCAAGGCGT
GAAGACCGAAGCGGCACGCCTGCTCGGCATCAGCTTTCGCTCCTTCCGCTACCGCCTGAAGAAGCTGGGGCTGGATCAGT
GA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(12-119)

Sigma-54 interaction domain (Sigma54_activat)

(147-313)

Bacterial regulatory protein, Fis family (HTH_8)

(409-449)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

56.696

98.896

0.561
  pilR Acinetobacter baumannii strain A118

46.368

100

0.479
  luxO Vibrio cholerae strain A1552

42.092

86.534

0.364