Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   RDV54_RS07385 Genome accession   NZ_CP133471
Coordinates   1551877..1553226 (+) Length   449 a.a.
NCBI ID   WP_000801588.1    Uniprot ID   A0AAX2L2X7
Organism   Streptococcus mitis strain LMG 14557     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1546877..1558226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV54_RS07350 (RDV54_07350) - 1547240..1547971 (+) 732 WP_001221869.1 response regulator transcription factor -
  RDV54_RS07355 (RDV54_07355) - 1548217..1548345 (+) 129 WP_000658220.1 smi_0059.1 family bacteriocin-like peptide -
  RDV54_RS07360 (RDV54_07360) - 1548357..1548512 (+) 156 WP_001004642.1 hypothetical protein -
  RDV54_RS07365 (RDV54_07365) - 1548546..1548719 (+) 174 WP_000180829.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  RDV54_RS07370 (RDV54_07370) - 1548843..1548995 (+) 153 WP_001180497.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  RDV54_RS07375 (RDV54_07375) - 1549020..1549175 (+) 156 WP_000732248.1 hypothetical protein -
  RDV54_RS07380 (RDV54_07380) comA 1549711..1551864 (+) 2154 WP_000668315.1 peptide cleavage/export ABC transporter ComA Regulator
  RDV54_RS07385 (RDV54_07385) comB 1551877..1553226 (+) 1350 WP_000801588.1 competence pheromone export protein ComB Regulator
  RDV54_RS07390 (RDV54_07390) purC 1553396..1554103 (+) 708 WP_000043282.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  RDV54_RS07395 (RDV54_07395) - 1554105..1554248 (+) 144 WP_078228447.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  RDV54_RS07400 (RDV54_07400) - 1554303..1558028 (+) 3726 WP_000361182.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49831.90 Da        Isoelectric Point: 6.0333

>NTDB_id=874513 RDV54_RS07385 WP_000801588.1 1551877..1553226(+) (comB) [Streptococcus mitis strain LMG 14557]
MKPEFLESAEFYNRRYHNFSSRVIVPMFLLLVFLLGFATLAEKEMSMSTRATVEPSRILANIQSTSNNRILVNHLEESKL
VKKGELLVQYQEGAEGVQAEAYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGTLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQGEENPQSKAQAVVQLEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEAESGRKVQGNLLDKGKITASEDGVLH
LNPETSDSTMVAEGALLAQLYPSLEKEGKVKLTAYLSSKDVARIKVGDSVRYTTTHDAKNQLFLDSTITSIDATATKTET
GNFFKIEAETNLTSKQAAKLRYGVEGRLQMITGRKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=874513 RDV54_RS07385 WP_000801588.1 1551877..1553226(+) (comB) [Streptococcus mitis strain LMG 14557]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTCCCCAT
GTTCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTTTGGCAGAGAAGGAGATGAGTATGTCTACTAGAGCTACTGTCG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAGTAAGCTG
GTTAAAAAGGGAGAACTGTTGGTTCAATATCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGGCCTATGCTAGTCAGCTGGA
CATGCTCAAGGATCAAAAAAAGCAATTGGAGTATTTGCAAAAGAGTCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAATTTGGCTACCAAGCCACCTTTCGTGACTACATCAGCCAAGCAGGTAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGTCAAACCCAAGCCGAAATCGGCACCCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTCT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCGCAATCTAAGGCACAAGCAGTTGTGCAGCTAGAAGCACAGCTTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGTTTAAG
CAGTCAATTGGAGTCTCTCAAATCACAACACTTGGCTAAGGTTGGTCAGGAATTGACCCTTCTAGACCAGAAAATTTTGG
AGGCAGAATCGGGTAGGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTACCATGGTAGCAGAAGGCGCCTTACTAGCCCAACTCTATCCGTCCTTGGAAAAAGA
AGGGAAAGTCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGGATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCTAAGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAAACT
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCTAAGCAGGCTGCAAAACTTCGATATGGGGTGGAAGGTCG
CCTGCAGATGATTACGGGCAGGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(310-423)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis NCTC 12261

100

100

1
  comB Streptococcus mitis SK321

95.323

100

0.953
  comB Streptococcus pneumoniae TIGR4

94.209

100

0.942
  comB Streptococcus pneumoniae Rx1

93.987

100

0.94
  comB Streptococcus pneumoniae D39

93.987

100

0.94
  comB Streptococcus pneumoniae R6

93.987

100

0.94
  comB Streptococcus gordonii str. Challis substr. CH1

55.778

100

0.559